Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Smaranda Willcox"'
Autor:
Allaura S. Cone, Yijun Zhou, Ryan P. McNamara, Anthony. B. Eason, Gabriel F. Arias, Justin T. Landis, Kyle W. Shifflett, Meredith G. Chambers, Runjie Yuan, Smaranda Willcox, Jack D. Griffith, Dirk P. Dittmer
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic caused the biggest public health crises in recent history. Many expect future coronavirus introductions into the human population. Hence, it is essential to understand
Externí odkaz:
https://doaj.org/article/7d31d2f9aa0f4ea7b7d5d5a76ddb2989
Autor:
Yijun Zhou, Runjie Yuan, Allaura S. Cone, Kyle W. Shifflett, Gabriel F. Arias, Alice Peng, Meredith G. Chambers, Ryan P. McNamara, Smaranda Willcox, Justin T. Landis, Yue Pan, Jack Griffith, Dirk P. Dittmer
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 6, Pp n/a-n/a (2023)
ABSTRACT Purifying extracellular vesicles (EVs) has been challenging because EVs are heterogeneous in cargo yet share similar sizes and densities. Most surface marker‐based affinity separation methods are limited to research or diagnostic scales. W
Externí odkaz:
https://doaj.org/article/8a14b7c58d914432a369d4a1c13f906d
Autor:
Ryan P. McNamara, Yijun Zhou, Anthony B. Eason, Justin T. Landis, Meredith G. Chambers, Smaranda Willcox, Tiffany A. Peterson, Blake Schouest, Nicholas J. Maness, Andrew G. MacLean, Lindsey M. Costantini, Jack D. Griffith, Dirk Peter Dittmer
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are secreted from all cell types and are intimately involved in tissue homeostasis. They are being explored as vaccine and gene therapy platforms, as well as potential biomarkers. As their size is below the diffr
Externí odkaz:
https://doaj.org/article/bfdb26258be341f2b7df2687fcdaa843
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Telomere loops (t-loops) are formed at the ends of chromosomes in species ranging from humans to worms, plants, and with genetic manipulation, some yeast. Recent in vitro studies demonstrated that transcription of telomeric DNA leads to highly effici
Externí odkaz:
https://doaj.org/article/22f174c7d19b4ac3b062244714f66caf
Autor:
Ĺubomír Tomáška, Jozef Nosek, Regina Sepšiová, Filip Červenák, Katarína Juríková, Katarína Procházková, Martina Neboháčová, Smaranda Willcox, Jack D. Griffith
Publikováno v:
Frontiers in Genetics, Vol 9 (2019)
Externí odkaz:
https://doaj.org/article/ae5f6380879f4cd6b7506ad4f844dd18
Autor:
Laura W. Dillon, Pankaj Kumar, Yoshiyuki Shibata, Yuh-Hwa Wang, Smaranda Willcox, Jack D. Griffith, Yves Pommier, Shunichi Takeda, Anindya Dutta
Publikováno v:
Cell Reports, Vol 11, Iss 11, Pp 1749-1759 (2015)
MicroDNAs are
Externí odkaz:
https://doaj.org/article/d9d44a78be4141a59b2fb57b3a4703ff
Autor:
Regina Sepsiova, Ivona Necasova, Smaranda Willcox, Katarina Prochazkova, Peter Gorilak, Jozef Nosek, Ctirad Hofr, Jack D Griffith, Lubomir Tomaska
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154225 (2016)
Telomeres of nuclear chromosomes are usually composed of an array of tandemly repeated sequences that are recognized by specific Myb domain containing DNA-binding proteins (telomere-binding proteins, TBPs). Whereas in many eukaryotes the length and s
Externí odkaz:
https://doaj.org/article/2d7e8220c00a478aaa9cb623d06ab857
Autor:
Samantha C Lewis, Priit Joers, Smaranda Willcox, Jack D Griffith, Howard T Jacobs, Bradley C Hyman
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004985 (2015)
Mitochondrial DNA (mtDNA) encodes respiratory complex subunits essential to almost all eukaryotes; hence respiratory competence requires faithful duplication of this molecule. However, the mechanism(s) of its synthesis remain hotly debated. Here we h
Externí odkaz:
https://doaj.org/article/8a7d960f1ab74accb31fa35fa99f02fc
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83582 (2014)
Although Blm and Top3α are known to form a minimal dissolvasome that can uniquely undo a double Holliday junction structure, the details of the mechanism remain unknown. It was originally suggested that Blm acts first to create a hemicatenane struct
Externí odkaz:
https://doaj.org/article/7b60ccbe58064a0094fda3a138ce7d6b
Autor:
Benjamin T. Ledford, Adam W. Akerman, Kui Sun, David C. Gillis, Jenna M. Weiss, Johnny Vang, Smaranda Willcox, Tristan D. Clemons, Hiroaki Sai, Ruomeng Qiu, Mark R. Karver, Jack D. Griffith, Nick D. Tsihlis, Samuel I. Stupp, John S. Ikonomidis, Melina R. Kibbe
Publikováno v:
ACS Nano
An abdominal aortic aneurysm (AAA) is a localized dilation of the aorta located in the abdomen that poses a severe risk of death when ruptured. The cause of AAA is not fully understood, but degradation of medial elastin due to elastolytic matrix meta