Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Smarajit Chakraborty"'
Autor:
Smarajit Chakraborty, Wee Kiat Ong, Winifred W. Y. Yau, Zhihong Zhou, K. N. Bhanu Prakash, Sue-Anne Toh, Weiping Han, Paul M. Yen, Shigeki Sugii
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our
Externí odkaz:
https://doaj.org/article/ca6b50ac2ba14c5889a290b4470f21f9
Autor:
Sandhya Sriram, Chengxiang Yuan, Smarajit Chakraborty, Winson Tay, Min Park, Asim Shabbir, Sue-Anne Toh, Weiping Han, Shigeki Sugii
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-8 (2019)
Abstract Background Visceral (VS) fat depot is known to have defective adipogenic functions compared to subcutaneous (SC) fat, but its mechanism of origin is unclear. Objective We tested our hypothesis that the degree of oxidative stress in adipose-d
Externí odkaz:
https://doaj.org/article/05061c38f2334f5ea602c378f15e08d0
Autor:
Chengxiang Yuan, Smarajit Chakraborty, Krishna Kanth Chitta, Subha Subramanian, Tau En Lim, Weiping Han, K. N. Bhanu Prakash, Shigeki Sugii
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Adipogenesis is essential in in vitro experimentation to assess differentiation capability of stem cells, and therefore, its accurate measurement is important. Quantitative analysis of adipogenic levels, however, is challenging and often sus
Externí odkaz:
https://doaj.org/article/9bff566f249f4fdc8fa20c78162b1925
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 918 (2021)
Adipose-derived stem cells (ASCs) have been increasingly used as a versatile source of mesenchymal stem cells (MSCs) for diverse clinical investigations. However, their applications often become complicated due to heterogeneity arising from various f
Externí odkaz:
https://doaj.org/article/167b0e331b1042ab85be080f288a0f40
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidi
Externí odkaz:
https://doaj.org/article/189cfa10e5dc4b49a66243af61ebc845
Autor:
Smarajit Chakraborty, Linda J. Kenney
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Bacteria survive and respond to diverse environmental conditions and during infection inside the host by systematic regulation of stress response genes. E. coli and S. Typhimurium can undergo large changes in intracellular osmolality (up to 1.8 Osmol
Externí odkaz:
https://doaj.org/article/45f812996cfa4473bc12b733633b7c78
Publikováno v:
PLoS Biology, Vol 13, Iss 4, p e1002116 (2015)
In bacteria, one paradigm for signal transduction is the two-component regulatory system, consisting of a sensor kinase (usually a membrane protein) and a response regulator (usually a DNA binding protein). The EnvZ/OmpR two-component system responds
Externí odkaz:
https://doaj.org/article/c6df8c9cb7964801a4e0f297367f5f00
Autor:
Chiradip Chatterjee, Sundramurthy Kumar, Smarajit Chakraborty, Yih Wan Tan, Ka Yin Leung, J Sivaraman, Yu-Keung Mok
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19208 (2011)
BackgroundThe putative needle complex subunit AscF forms a ternary complex with the chaperones AscE and AscG in the type III secretion system of Aeromonas hydrophila so as to avoid premature assembly. Previously, we demonstrated that the C-terminal r
Externí odkaz:
https://doaj.org/article/680e146151a5443a853a01a62a8de0aa
Autor:
Chacko Jobichen, Smarajit Chakraborty, Mo Li, Jun Zheng, Lissa Joseph, Yu-Keung Mok, Ka Yin Leung, J Sivaraman
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12910 (2010)
The recently identified type VI secretion system (T6SS) is implicated in the virulence of many gram-negative bacteria. Edwardsiella tarda is an important cause of hemorrhagic septicemia in fish and also gastro- and extra-intestinal infections in huma
Externí odkaz:
https://doaj.org/article/47a4ccb1ff6c499d87bf59b588576200
Autor:
Paul M. Yen, K. N. Bhanu Prakash, Shigeki Sugii, Wee Kiat Ong, Winifred W. Yau, Weiping Han, Smarajit Chakraborty, Zhihong Zhou, Sue-Anne Toh
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our understa