Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida , Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme.

Autor: Avalon NE; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Nafie J; BioTools, Inc., Jupiter, Florida 33458, United States., De Marco Verissimo C; Molecular Parasitology Laboratory (MPL), Centre for One Health and Ryan Institute, School of Natural Science, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland., Warrensford LC; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Dietrick SG; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Pittman AR; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Young RM; School of Natural Sciences and Ryan Institute, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland., Kearns FL; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Smalley T; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, United States., Binning JM; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, United States., Dalton JP; Molecular Parasitology Laboratory (MPL), Centre for One Health and Ryan Institute, School of Natural Science, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland., Johnson MP; School of Natural Sciences and Ryan Institute, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland., Woodcock HL; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States., Allcock AL; School of Natural Sciences and Ryan Institute, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland., Baker BJ; Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States.

Publikováno v: Journal of natural products [J Nat Prod] 2022 May 27; Vol. 85 (5), pp. 1315-1323. Date of Electronic Publication: 2022 May 12.

Effect of antibiotics on enterocystoplasty urinary nitrosamine levels

Autor: Greenwell, T.J, Woodhams, S.D, Smalley, T, Mundy, A.R

Publikováno v: In Urology 2001 58(5):660-664

The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein Expression.

Autor: Smalley T; Department of Chemistry, University of South Florida, Tampa, FL, United States., Metcalf R; Department of Chemistry, University of South Florida, Tampa, FL, United States., Patel R; Department of Chemistry, University of South Florida, Tampa, FL, United States., Islam SMA; Department of Chemistry, University of South Florida, Tampa, FL, United States., Bommareddy RR; Department of Chemistry, University of South Florida, Tampa, FL, United States., Acevedo-Duncan M; Department of Chemistry, University of South Florida, Tampa, FL, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2020 Feb 27; Vol. 10, pp. 209. Date of Electronic Publication: 2020 Feb 27 (Print Publication: 2020).

Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets.

Autor: Rukhlenko, Oleksii S.¹ (AUTHOR), Imoto, Hiroaki¹ (AUTHOR), Tambde, Ayush^1,2 (AUTHOR), McGillycuddy, Amy^1,3 (AUTHOR), Junk, Philipp¹ (AUTHOR), Tuliakova, Anna¹ (AUTHOR), Kolch, Walter^1,4 (AUTHOR), Kholodenko, Boris N.^1,4,5 (AUTHOR) boris.kholodenko@ucd.ie

Publikováno v: Cancers. Jul2024, Vol. 16 Issue 13, p2354. 25p.

Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade.

Autor: Apostolatos AH; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Ratnayake WS; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Win-Piazza H; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Apostolatos CA; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Smalley T; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Kang L; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Salup R; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA., Hill R; Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL 33620, USA., Acevedo-Duncan M; Department of Chemistry, University of South Florida, Tampa, FL 33620, USA.

Publikováno v: International journal of oncology [Int J Oncol] 2018 Nov; Vol. 53 (5), pp. 1836-1846. Date of Electronic Publication: 2018 Aug 28.