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pro vyhledávání: '"Smallbone, K"'
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Akademický článek
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Autor:
Gatenby, R A1, Smallbone, K2, Maini, P K2, Rose, F3, Averill, J4, Nagle, R B4, Worrall, L3, Gillies, R J1
Publikováno v:
British Journal of Cancer. 9/3/2007, Vol. 97 Issue 5, p646-653. 8p. 3 Color Photographs, 1 Diagram, 2 Graphs.
Acidic pH is a common characteristic of human tumours. It has a significant impact on tumour progression and response to therapies. In this paper, we develop a simple model of three-dimensional tumour growth to examine the role of acidosis in the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::dabc3b7268516a6d4c2ebb36f2a91562
https://ora.ox.ac.uk/objects/uuid:311e7863-5e92-45b9-b108-08010d4d8916
https://ora.ox.ac.uk/objects/uuid:311e7863-5e92-45b9-b108-08010d4d8916
Autor:
Smallbone, K
Acidic pH is a common characteristic of human tumours. It has a significant impact on tumour progression and response to therapies. In this thesis, we utilise mathematical modelling to examine the role of acidosis in the interaction between normal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::821acfc78ccdd6034aad26846f4fe155
https://ora.ox.ac.uk/objects/uuid:9b97dc21-3c79-4af1-8b9f-6168c79dd20a
https://ora.ox.ac.uk/objects/uuid:9b97dc21-3c79-4af1-8b9f-6168c79dd20a
Tumour tissue characteristically experiences fluctuations in substrate supply. This unstable microenvironment drives constitutive metabolic changes within cellular populations and, ultimately, leads to a more aggressive phenotype. Previously, variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::cc75aa42235f41c9dc26821c199b51c1
https://ora.ox.ac.uk/objects/uuid:12cabaa9-3588-4de4-ba6c-68fd455f791c
https://ora.ox.ac.uk/objects/uuid:12cabaa9-3588-4de4-ba6c-68fd455f791c
Autor:
Herrgard, M.J., Swainston, N., Dobson, P., Dunn, W.B., Arga, K.Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, E.R., Heinemann, M., Hucka, M., Li, P., Liebermeister, W., Mo, M.L., Oliveira, A.P., Petranovic, D., Pettifer, S., Simeonides, E., Smallbone, K., Spasi, I., Weichart, D., Brent, R., Broomhead, D.S., Westerhoff, H.V., Kirdar, B., Penttila, M., Klipp, E., Paton, N., Palsson, B.O., Sauer, U., Oliver, S.G., Mendes, P., Nielsen, J., Kell, D.B.
Publikováno v:
Herrgard, M J, Swainston, N, Dobson, P, Dunn, W B, Arga, K Y, Arvas, M, Bluthgen, N, Borger, S, Costenoble, E R, Heinemann, M, Hucka, M, Li, P, Liebermeister, W, Mo, M L, Oliveira, A P, Petranovic, D, Pettifer, S, Simeonides, E, Smallbone, K, Spasi, I, Weichart, D, Brent, R, Broomhead, D S, Westerhoff, H V, Kirdar, B, Penttila, M, Klipp, E, Paton, N, Palsson, B O, Sauer, U, Oliver, S G, Mendes, P, Nielsen, J & Kell, D B 2008, ' A consensus yeast metabolic network obtained from a community approach to systems biology. ', Nature Biotechnology, vol. 26, pp. 1155-1160 . https://doi.org/10.1038/nbt1492
Nature Biotechnology, 26, 1155-1160. Nature Publishing Group
Nature Biotechnology, 26, 1155-1160. Nature Publishing Group
Genomic data allow the large-scale manual or semi-automated assembly of metabolic network reconstructions, which provide highly curated organism-specific knowledge bases. Although several genome-scale network reconstructions describe Saccharomyces ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::105c0c903efa7751f422a332c625af71
https://hdl.handle.net/1871.1/afa00df3-5f6f-431b-b27c-10c5b6d907eb
https://hdl.handle.net/1871.1/afa00df3-5f6f-431b-b27c-10c5b6d907eb
Autor:
Wyche, K. P., Monks, P. S., Smallbone, K. L., Hamilton, J. F., Alfarra, M. R., Rickard, A. R., McFiggans, G. B., Jenkin, M. E., Bloss, W. J., Ryan, A. C., Hewitt, C. N., MacKenzie, A. R.
Publikováno v:
Atmospheric Chemistry and Physics, Vol 15, Iss 14, Pp 8077-8100 (2015)
Highly non-linear dynamical systems, such as those found in atmospheric chemistry, necessitate hierarchical approaches to both experiment and modelling in order to ultimately identify and achieve fundamental process-understanding in the full open sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e6f5887b17eca36e5ffad4ccf16f43d9
https://eprints.whiterose.ac.uk/90662/1/acp_15_8077_2015_1.pdf
https://eprints.whiterose.ac.uk/90662/1/acp_15_8077_2015_1.pdf
Akademický článek
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