Reactivity of (Vicinal) Carbonyl Compounds with Urea

Autor: Jong, Jacobus A W, Smakman, Robert, Moret, Marc-Etienne, Verhaar, Marianne C, Hennink, Wim E, Gerritsen, Karin G F, Van Nostrum, Cornelus F, Afd Pharmaceutics, Sub Organic Chemistry and Catalysis, Pharmaceutics

Publikováno v: ACS Omega, Vol 4, Iss 7, Pp 11928-11937 (2019)
ACS Omega
ACS Omega, 4(7), 11928. American Chemical Society
ACS omega, 4(7), 11928

Urea removal from dialysate is the major obstacle in realization of a miniature dialysis device, based on continuous dialysate regeneration in a closed loop, used for the treatment of patients suffering from end-stage kidney disease. For the developm

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https://doaj.org/article/29d3ca6f777142278e813b70e4fbab6a

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A Ninhydrin-Type Urea Sorbent for the Development of a Wearable Artificial Kidney.

Autor: Jong JAW; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands.; Department of Nephrology and Hypertension, University Medical Centre Utrecht, 3584 CX, Utrecht, the Netherlands., Guo Y; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands., Hazenbrink D; Department of Nephrology and Hypertension, University Medical Centre Utrecht, 3584 CX, Utrecht, the Netherlands., Douka S; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands., Verdijk D; MercaChem B.V., Kerkenbos 1013, 6546 BB, Nijmegen, the Netherlands., van der Zwan J; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands., Houben K; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands., Baldus M; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands., Scheiner KC; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands., Dalebout R; Inorganic Chemistry and Catalysis, Debye Institute for Nanomaterials Science, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Centre Utrecht, 3584 CX, Utrecht, the Netherlands., Smakman R; Innovista, Raadhuisstraat 1, 1393 NW, Nigtevecht, the Netherlands., Hennink WE; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands., Gerritsen KGF; Department of Nephrology and Hypertension, University Medical Centre Utrecht, 3584 CX, Utrecht, the Netherlands., van Nostrum CF; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands.

Publikováno v: Macromolecular bioscience [Macromol Biosci] 2020 Mar; Vol. 20 (3), pp. e1900396. Date of Electronic Publication: 2020 Feb 17.