Výsledky vyhledávání - "Smad1 Protein/genetics/metabolism"

BAMBI elimination enhances alternative TGF-beta signaling and glomerular dysfunction in diabetic mice

Autor: Jia Fu, Nicolas Guillot, John Cijiang He, Maja T. Lindenmeyer, Xuezhu Li, Niansong Wang, Kyung Lee, Clemens D. Cohen, Peter Y. Chuang, Wenzhen Xiao, Ying Fan, Raymond C. Harris, Margaret H. Baron, Detlef Schlöndorff

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2015, 64 (6), pp.2220-33. ⟨10.2337/db14-1397⟩

International audience; BMP, activin, membrane-bound inhibitor (BAMBI) acts as a pseudo-receptor for the transforming growth factor (TGF)-beta type I receptor family and a negative modulator of TGF-beta kinase signaling, and BAMBI(-/-) mice show mild

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcedf278915b3839c29db19680ebe33
https://hal.archives-ouvertes.fr/hal-01850503

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BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production

Autor: Paul D. Upton, Mark J.D. Griffiths, Stephen J. Wort, Nicholas W. Morrell, Rachel J. Davies, John E. S. Park, Dongmin Shao, Patricia deSouza, Ian M. Adcock

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 1, p e30075 (2012)

Background Bone morphogenetic proteins (BMPs) and their receptors, such as bone morphogenetic protein receptor (BMPR) II, have been implicated in a wide variety of disorders including pulmonary arterial hypertension (PAH). Similarly, endothelin-1 (ET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92a40d2f1c018a56498f5821e1b2409
https://www.repository.cam.ac.uk/handle/1810/271012

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