Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Smad signaling pathway"'
Autor:
Mingzhu Deng, Feifei Gao, Tianfeng Liu, Weiqiang Zhan, Juanhua Quan, Ziquan Zhao, Xuyang Wu, Zhuolan Zhong, Hong Zheng, Jiaqi Chu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Bone defects, resulting from substantial bone loss that exceeds the natural self-healing capacity, pose significant challenges to current therapeutic approaches due to various limitations. In the quest for alternative therapeutic
Externí odkaz:
https://doaj.org/article/d17d789a5bf14e58b3d52c9e5178df59
HUC-MSCs combined with platelet lysate treat diabetic chronic cutaneous ulcers in Bama miniature pig
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 1138-1149 (2024)
Human umbilical cord mesenchymal stem cells (HUC-MSCs) and platelet lysate (PL) shows potential of wound healing. However, MSCs in combination with PL for wound healing is still lacking. In this study, we presented high glucose cultured wound related
Externí odkaz:
https://doaj.org/article/0edf200f53f3403eb9d0b562a63cfa55
Publikováno v:
Journal of Men's Health, Vol 20, Iss 4, Pp 127-132 (2024)
Hepatocellular carcinoma (HCC), as one usual tumor, and owns the significant mortality rates. The involvement of the coupling of ubiquitin conjugation to endoplasmic reticulum degradation (CUE) domain containing 1 (CUEDC1) in cancer progression, eith
Externí odkaz:
https://doaj.org/article/6b802cde8e0f4f74895f5ec0d92d8088
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Recombinant human bone morphogenetic protein-2 (rhBMP-2), a key regulator of osteogenesis, induces the differentiation of mesenchymal cells into cartilage or bone tissues. Early orthopedic and dental studies often used mammalian cell-derived
Externí odkaz:
https://doaj.org/article/5007aa69521644a98634eb304a362edb
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Ankylosing spondylitis (AS) is a refractory autoimmune disease, whose typical pathology is the development of inflammation to ossification and ankylosis. Histone deacetylase 1 (HDAC1) is considered to be a key factor involved in inflammatory
Externí odkaz:
https://doaj.org/article/7e438ac5f9f94e969920c1896ddeebc6
Autor:
Atukuri Dorababu, Manikantha Maraswami
Publikováno v:
Molecules, Vol 28, Iss 9, p 3674 (2023)
A condition of scarring of lung tissue due to a wide range of causes (such as environmental pollution, cigarette smoking (CS), lung diseases, some medications, etc.) has been reported as pulmonary fibrosis (PF). This has become a serious problem all
Externí odkaz:
https://doaj.org/article/0e93a37e8ecb4b7b803ffec0b53413ee
Autor:
Xinchao Miao, Kunimichi Niibe, Yunyu Fu, Maolin Zhang, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption. Ameloblast differentiation is regulated by multiple signaling mol
Externí odkaz:
https://doaj.org/article/97c1d00f9dec430e873d852651418853
Autor:
Bruna Moretto Rodrigues, Lucas Solla Mathias, Igor de Carvalho Deprá, Sarah Santiloni Cury, Miriane de Oliveira, Regiane Marques Castro Olimpio, Maria Teresa De Sibio, Bianca Mariani Gonçalves, Célia Regina Nogueira
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Thyroid hormones play a significant role in bone development and maintenance, with triiodothyronine (T3) particularly being an important modulator of osteoblast differentiation, proliferation, and maintenance. However, details of the biol
Externí odkaz:
https://doaj.org/article/7f40894a58b646eda8897c3957c63bcf
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Capsular contracture caused by silicone rubber is a critical issue in plastic surgery that urgently needs to be solved. Studies have shown that carbon ion implant in silicone rubber (carbon silicone rubber, C-SR) can significantly improve the capsula
Externí odkaz:
https://doaj.org/article/2d10e981cb8f42d1ba77f55b97727ecf
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 163 (2023)
Idiopathic pulmonary fibrosis is a chronic interstitial lung disease whose pathogenesis involves a complex interaction of cell types and signaling pathways. Lung epithelial cells responding to repeated injury experience persistent inflammation and su
Externí odkaz:
https://doaj.org/article/a87182b6d32549c7a38d4bc1db9024b3