Zobrazeno 1 - 10
of 1 175
pro vyhledávání: '"Smad Signaling"'
Autor:
Mingzhu Deng, Feifei Gao, Tianfeng Liu, Weiqiang Zhan, Juanhua Quan, Ziquan Zhao, Xuyang Wu, Zhuolan Zhong, Hong Zheng, Jiaqi Chu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Bone defects, resulting from substantial bone loss that exceeds the natural self-healing capacity, pose significant challenges to current therapeutic approaches due to various limitations. In the quest for alternative therapeutic
Externí odkaz:
https://doaj.org/article/d17d789a5bf14e58b3d52c9e5178df59
Publikováno v:
Journal of Men's Health, Vol 20, Iss 4, Pp 127-132 (2024)
Hepatocellular carcinoma (HCC), as one usual tumor, and owns the significant mortality rates. The involvement of the coupling of ubiquitin conjugation to endoplasmic reticulum degradation (CUE) domain containing 1 (CUEDC1) in cancer progression, eith
Externí odkaz:
https://doaj.org/article/6b802cde8e0f4f74895f5ec0d92d8088
Autor:
Guoqian Liu, Mengwei Li, Zimei Zeng, Qi Fan, Xinxin Ren, Zhexin Wang, Yaoqi Sun, Yulin He, Lunquan Sun, Yuezhen Deng, Shupeng Liu, Chenxi Zhong, Jie Gao
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract The alteration of metabolic processes has been found to have significant impacts on the development of hepatocellular carcinoma (HCC). Nevertheless, the effects of dysfunction of tyrosine metabolism on the development of HCC remains to be di
Externí odkaz:
https://doaj.org/article/549d7e173f0640f5b8e80acc762e6c09
Autor:
Tianming Qiu, Kun Hou, Jingyuan Zhang, Ningning Wang, Xiaofeng Yao, Guang Yang, Liping Jiang, Jikun Dong, Menglong Miao, Jie Bai, Xiance Sun
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 278, Iss , Pp 116435- (2024)
The compound known as Sodium arsenite (NaAsO2), which is a prevalent type of inorganic arsenic found in the environment, has been strongly associated with liver fibrosis (LF), a key characteristic of nonalcoholic fatty liver disease (NAFLD), which ha
Externí odkaz:
https://doaj.org/article/30feb4f8b0b04e5293a252967761bb61
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5889-5907 (2023)
Abstract Background Gliomas are a group of primary intracranial tumors with high morbidity and mortality. The previous researches indicated a crucial role of CKS2 (cyclin‐dependent kinases regulatory subunit 2) in hepatocellular carcinoma and breas
Externí odkaz:
https://doaj.org/article/ea67a342b16a4e4f8cafff00b620a6c8
Autor:
Francesca Lombardi, Francesca Rosaria Augello, Serena Artone, Blerina Bahiti, Jenna Marie Sheldon, Maurizio Giuliani, Maria Grazia Cifone, Paola Palumbo, Benedetta Cinque
Publikováno v:
Journal of Inflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Abnormal and deregulated skin wound healing associated with prolonged inflammation may result in dermal fibrosis. Since the current therapeutic strategies revealed unsatisfactory, the investigation of alternative approaches such a
Externí odkaz:
https://doaj.org/article/c259cf4276f242a5b5e2d4a9ba48ad01
Publikováno v:
口腔疾病防治, Vol 30, Iss 12, Pp 884-889 (2022)
Dental and craniofacial bone development is a highly coordinated process that is tightly controlled by genetics and influenced by complex environments. The abnormal regulation of many development-related signaling molecules may lead to abnormal tooth
Externí odkaz:
https://doaj.org/article/82ba197c697848e4851c3a29121080a0
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Recombinant human bone morphogenetic protein-2 (rhBMP-2), a key regulator of osteogenesis, induces the differentiation of mesenchymal cells into cartilage or bone tissues. Early orthopedic and dental studies often used mammalian cell-derived
Externí odkaz:
https://doaj.org/article/5007aa69521644a98634eb304a362edb
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Ankylosing spondylitis (AS) is a refractory autoimmune disease, whose typical pathology is the development of inflammation to ossification and ankylosis. Histone deacetylase 1 (HDAC1) is considered to be a key factor involved in inflammatory
Externí odkaz:
https://doaj.org/article/7e438ac5f9f94e969920c1896ddeebc6
Autor:
Maria Pitou, Eleni Papachristou, Dimitrios Bratsios, Georgia-Maria Kefala, Anastasia S. Tsagkarakou, Demetrios D. Leonidas, Amalia Aggeli, Georgios E. Papadopoulos, Rigini M. Papi, Theodora Choli-Papadopoulou
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3182 (2023)
Τransforming growth factor β1 (TGF-β1) comprises a key regulator protein in many cellular processes, including in vivo chondrogenesis. The treatment of human dental pulp stem cells, separately, with Leu83-Ser112 (C-terminal domain of TGF-β1), as
Externí odkaz:
https://doaj.org/article/dd98fb2b954f438699bd34a7c11083a7