Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Smad Proteins/metabolism"'
Autor:
Anja Seckinger, Giorgio Mori, Volker Martin, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Slobodan Vukicevic, Francesca Posa, Dirk Hose
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585faf31fe1d433826775658439c7746
Autor:
Séverine Mazaud Guittot, Sandra Fontanière, Alain Calender, Nader Hussein, Anne-Marie Morera, Nathalie di Clemente, Huguette Casse, Jieli Lu, Chang X. Zhang
Publikováno v:
Endocrine-Related Cancer
Endocrine-Related Cancer, BioScientifica, 2008, 15 (1), pp. 217-27. ⟨10.1677/ERC-06-0046⟩
Endocrine-Related Cancer, BioScientifica, 2008, 15 (1), pp. 217-27. ⟨10.1677/ERC-06-0046⟩
International audience; Multiple endocrine neoplasia type 1 (MEN1) results from the mutation of the predisposing gene, MEN1. Heterozygous Men1 mutant mice previously generated by several laboratories, including ours, mimic largely MEN1 pathology. Int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6663f7a483228b6087407961dd721d71
https://doi.org/10.1677/erc-06-0046
https://doi.org/10.1677/erc-06-0046
Autor:
M. Luisa Pérez-Lozano, Abelardo Aguilera, Lorea Mendoza, Jacob van den Born, Patricia Albar-Vizcaíno, Guadalupe González-Mateo, Marta Ruiz-Ortega, Marta Ramírez-Huesca, Jesús Loureiro, Robert H. J. Beelen, Manuel López-Cabrera, Alberto Ortiz, Rafael Selgas, Margot N. Schilte, Luiz S. Aroeira
Publikováno v:
Nephrology, Dialysis, Transplantation, 25(4), 1098-1108. Oxford University Press
Loureiro, J, Schilte, M N, Aguilera, A, Albar-Vizcaino, P, Ramirez-Huesca, M, Perez-Lozano, M L, Gonzalez-Mateo, G, Aroeira, L S, Selgas, R, Mendoza, L, Ortiz, A, Ruiz-Ortega, M, van den Born, J, Beelen, R H J & Lopez-Cabrera, M 2010, ' BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure ', Nephrology, Dialysis, Transplantation, vol. 25, no. 4, pp. 1098-1108 . https://doi.org/10.1093/ndt/gfp618
Loureiro, J, Schilte, M N, Aguilera, A, Albar-Vizcaino, P, Ramirez-Huesca, M, Perez-Lozano, M L, Gonzalez-Mateo, G, Aroeira, L S, Selgas, R, Mendoza, L, Ortiz, A, Ruiz-Ortega, M, van den Born, J, Beelen, R H J & Lopez-Cabrera, M 2010, ' BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure ', Nephrology, Dialysis, Transplantation, vol. 25, no. 4, pp. 1098-1108 . https://doi.org/10.1093/ndt/gfp618
BACKGROUND: During peritoneal dialysis (PD), mesothelial cells (MC) undergo an epithelial-to-mesenchymal transition (EMT), and this process is associated with peritoneal membrane (PM) damage. Bone morphogenic protein-7 (BMP-7) antagonizes transformin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86da525c51d65cb7cc762c73bfa60b5a
https://doi.org/10.1093/ndt/gfp618
https://doi.org/10.1093/ndt/gfp618
The integrated roles of small GTPases in executing the transforming growth factor beta (TGFbeta) signaling pathway have attracted increasing attention in recent years. In this review, we summarize recent findings on TGFbeta signaling during receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::c8dc09a0149fb5edcf0aef14a3616cbe
http://olympias.lib.uoi.gr/jspui/handle/123456789/22796
http://olympias.lib.uoi.gr/jspui/handle/123456789/22796
Publikováno v:
Europe PubMed Central
The transforming growth factor-beta (TGF-beta) plays a pivotal role in the pathobiology of human gliomas: during carcinogenesis, it turns from a tumor suppressor to a tumor promoter. The traditional Smad pathway and the more recently discovered MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4af03632a92b2856b52a1ea8f23ba7
https://pubmed.ncbi.nlm.nih.gov/17203233
https://pubmed.ncbi.nlm.nih.gov/17203233
Autor:
Erwan Le Scolan, Alain Mauviel, Delphine Javelaud, Vasileia I. Alexaki, Léon C van Kempen, Kunxin Luo
Publikováno v:
Molecular Cancer
Molecular Cancer, BioMed Central, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 10:2. BMC
Molecular Cancer, Vol 10, Iss 1, p 2 (2011)
Molecular Cancer, BioMed Central, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 10:2. BMC
Molecular Cancer, Vol 10, Iss 1, p 2 (2011)
Background SKI and SnoN proteins have been shown to inhibit TGF-β signaling, acting both as transcriptional co-repressors in the cell nucleus, and as sequestrators of SMAD proteins in the cytoplasm. TGF-β, on the other hand, induces rapid, proteaso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb74f62e5e96127a24e2466f4ff6a9a6