Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sm, Picksley"'
Autor:
David Lane, Cw, Stephen, Ca, Midgley, Sparks A, Tr, Hupp, Da, Daniels, Greaves R, Reid A, Vojtesek B, Sm, Picksley
Publikováno v:
Europe PubMed Central
The identification and characterisation of the p53 tumour suppressor has relied extensively on the use of immunological reagents. To facilitate further characterisation of the murine p53 protein (Mp53), and its interaction with other proteins, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7ac80a08550eb773df88caaac0895c7
https://pubmed.ncbi.nlm.nih.gov/8649788
https://pubmed.ncbi.nlm.nih.gov/8649788
Publikováno v:
Europe PubMed Central
The function of p53 is modulated by binding to a number of cellular and viral proteins, such as MDM2 and SV40 large T antigen. An initial immunochemical characterization of the p53-MDM2 complex in a rat fibroblast cell line (Clone 6) suggested that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ca6b31dc7550ecb41dff9c726d2751e5
https://pubmed.ncbi.nlm.nih.gov/8058315
https://pubmed.ncbi.nlm.nih.gov/8058315
Autor:
Böttger V, Böttger A, Sf, Howard, Sm, Picksley, Chène P, Garcia-Echeverria C, Hk, Hochkeppel, David Lane
Publikováno v:
Europe PubMed Central
The oncogene mdm2 and its human homologue hdm2 bind to the tumour suppressor protein p53 and inactivate its function as a transcription factor. This has been implied as a possible mechanism for cancer development in several tumours including human sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d363a87c4e22288f9df69ac417b12fb3
http://europepmc.org/abstract/med/8950981
http://europepmc.org/abstract/med/8950981
Publikováno v:
British Journal of Cancer; Jun1995, Vol. 71 Issue 6, p1253-1256, 4p