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pro vyhledávání: '"Sloss, Olivia"'
Autor:
Sloss, Olivia
Drugs that alter microtubule dynamics are often used in chemotherapy regimes in combination with other agents in order to treat various cancers. Despite the success over many years, there remain problems in toxicity, resistance and predictability to
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701101
Autor:
Topham, Caroline, Tighe, Anthony, Ly, Peter, Bennett, Ailsa, Sloss, Olivia, Nelson, Louisa, Ridgway, Rachel A., Huels, David, Littler, Samantha, Schandl, Claudia, Sun, Ying, Bechi, Beatrice, Procter, David J., Sansom, Owen J., Cleveland, Don W., Taylor, Stephen S.
Publikováno v:
In Cancer Cell 13 July 2015 28(1):129-140
Akademický článek
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Autor:
Smith, Michael P, Rowling, Emily J, Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K, Sloss, Olivia, McEntegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P, Dummer, Reinhard, Frederick, Dennie T, Andrews, Miles C, Cooper, Zachary A, Flaherty, Keith T, Wargo, Jennifer A, Wellbrock, Claudia
Publikováno v:
Smith, M, Rowling, E, Miskolczi, Z, Ferguson, J, Spoerri, L, Haass, N K, Sloss, O, McEntegart, S, Arozarena, I, Kriegsheim, A V, Rodriguez, J, Brunton, H, Kmarashev, J, Levesque, M P, Dummer, R, Frederick, D T, Flaherty, K T, Andrews, M, Cooper, Z A, Wargo, J A & Wellbrock, C 2017, ' Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure ', EMBO Molecular Medicine . https://doi.org/10.15252/emmm.201607156
EMBO Molecular Medicine
Smith, M P, Rowling, E J, Miskolczi, Z, Ferguson, J, Spoerri, L, Haass, N K, Sloss, O, McEntegart, S, Arozarena, I, von Kriegsheim, A, Rodriguez, J, Brunton, H, Kmarashev, J, Levesque, M P, Dummer, R, Frederick, D T, Andrews, M C, Cooper, Z A, Flaherty, K T, Wargo, J A & Wellbrock, C 2017, ' Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure ', EMBO Molecular Medicine . https://doi.org/10.15252/emmm.201607156
EMBO Molecular Medicine
Smith, M P, Rowling, E J, Miskolczi, Z, Ferguson, J, Spoerri, L, Haass, N K, Sloss, O, McEntegart, S, Arozarena, I, von Kriegsheim, A, Rodriguez, J, Brunton, H, Kmarashev, J, Levesque, M P, Dummer, R, Frederick, D T, Andrews, M C, Cooper, Z A, Flaherty, K T, Wargo, J A & Wellbrock, C 2017, ' Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure ', EMBO Molecular Medicine . https://doi.org/10.15252/emmm.201607156
Approaches to prolong responses to BRAF targeting drugs in melanoma patients are challenged by phenotype heterogeneity. Melanomas of a "MITF-high" phenotype usually respond well to BRAF inhibitor therapy, but these melanomas also contain subpopulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8cdcf444aebcef9c5474956100dbcf15
https://doi.org/10.15252/emmm.201607156
https://doi.org/10.15252/emmm.201607156
Autor:
Bennett, Ailsa, Sloss, Olivia, Topham, Caroline, Nelson, Louisa, Tighe, Anthony, Taylor, Stephen S.
Publikováno v:
Open Biology
Open Biology, Vol 6, Iss 8 (2016)
Bennett, A, Sloss, O, Topham, C, Nelson, L, Tighe, A & Taylor, S 2016, ' Inhibition of Bcl-xL sensitizes cells to mitotic blockers but not mitotic drivers ', Open Biology . https://doi.org/10.1098/rsob.160134
Open Biology, Vol 6, Iss 8 (2016)
Bennett, A, Sloss, O, Topham, C, Nelson, L, Tighe, A & Taylor, S 2016, ' Inhibition of Bcl-xL sensitizes cells to mitotic blockers but not mitotic drivers ', Open Biology . https://doi.org/10.1098/rsob.160134
Cell fate in response to an aberrant mitosis is governed by two competing networks: the spindle assembly checkpoint (SAC) and the intrinsic apoptosis pathway. The mechanistic interplay between these two networks is obscured by functional redundancy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7ddb3529f6237a91577d772a9f330e2b
Akademický článek
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