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Reporter cell lines for detection of pertussis toxin in acellular pertussis vaccines as a functional animal-free alternative to the in vivo histamine sensitization test

Autor: Hoonakker, Marieke E., Verhagen, Lisa M., van der Maas, Larissa, Sloots, Arjen, Hendriksen, Coenraad F.M.

Publikováno v: In Vaccine 22 February 2017 35(8):1152-1160

Activation of Canine, Mouse and Human TLR2 and TLR4 by Inactivated Leptospira Vaccine Strains

Autor: Novak, Andreja, Pupo, Elder, Van't Veld, Esther, Rutten, Victor P M G, Broere, Femke, Sloots, Arjen, dI&I RA-I&I I&I, IOV CCB, Immunologie, Interne geneeskunde GD, LS Virologie, CS_Welfare & emerging diseases

Publikováno v: Frontiers in Immunology, 13, 1. Frontiers Media S.A.
Frontiers in Immunology

CanineLeptospiravaccines contain inactivated strains of pathogenicLeptospira, the causative agents of leptospirosis. For an effective response to vaccination, activation of the innate immune systemviapattern recognition receptors such as TLRs is cruc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aff7afde868ab5110c33b72cffa7520
https://doi.org/10.3389/fimmu.2022.823058

Overcoming scientific barriers in the transition from to non-animal batch testing of human and veterinary vaccines

Autor: van den Biggelaar, Robin H G A, Hoefnagel, Marcel H N, Vandebriel, Rob J, Sloots, Arjen, Hendriksen, Coenraad F M, van Eden, Willem, Rutten, Victor P M G, Jansen, Christine A

Before release, vaccine batches are assessed for quality to evaluate whether they meet the product specifications. Vaccine batch tests, in particular of inactivated and toxoid vaccines, still largely rely on in vivo methods. Improved vaccine producti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::6d5fa6ec41f73d99bfea658e93aa012c
http://hdl.handle.net/10029/625316

Overcoming scientific barriers in the transition from in vivo to non-animal batch testing of human and veterinary vaccines

Autor: Biggelaar, Robin H. G. A. van den, Hoefnagel, Marcel H.N., Vandebriel, Rob J., Sloots, Arjen, Hendriksen, Coenraad F.M., Eden, Willem van, Rutten, Victor P. M. G., Jansen, Christine A., LS Virologie, AISS LAS/3'R Centre ULS, Algemeen Onderzoek DGK, Immunologie, dI&I RA-I&I I&I

Publikováno v: Expert Review of Vaccines, 20(10), 1221-1233
Expert Review of Vaccines 20 (2021) 10
Expert Review of Vaccines, 20(10), 1221. Expert Reviews Ltd.

Introduction Before release, vaccine batches are assessed for quality to evaluate whether they meet the product specifications. Vaccine batch tests, in particular of inactivated and toxoid vaccines, still largely rely on in vivo methods. Improved vac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792171eee065dc18fc714c87cdbed7c
https://doi.org/10.1080/14760584.2021.1977628