Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Autor: Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Anorexia Nervosa Genetics Initiative, Hanscombe KB, Purves KL, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Raquel Rabionet Janssen, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM

Publikováno v: NATURE GENETICS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and serious illness 1 , affecting 0.9-4% of women and 0.3% of men 2-4 , with twin-based heritability estimates of 50-60% 5 . Mortality rates are higher than those in othe

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An overview and investigation of relapse predictors in anorexia nervosa: A systematic review and meta-analysis.

Autor: de Rijk ESJ; GGZ Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands.; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands., Almirabi D; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Robinson L; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Schmidt U; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., van Furth EF; GGZ Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands.; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands., Slof-Op 't Landt MCT; GGZ Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands.; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.

Publikováno v: The International journal of eating disorders [Int J Eat Disord] 2024 Jan; Vol. 57 (1), pp. 3-26. Date of Electronic Publication: 2023 Oct 19.

Common Genetic Variation and Age of Onset of Anorexia Nervosa.

Autor: Watson HJ; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; School of Psychology, Curtin University, Perth, Western Australia, Australia.; Division of Paediatrics, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia., Thornton LM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Yilmaz Z; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Baker JH; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Coleman JRI; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Adan RAH; Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, the Netherlands.; Altrecht Eating Disorders Rintveld, Zeist, the Netherlands., Alfredsson L; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Andreassen OA; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Ask H; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway., Berrettini WH; Department of Psychiatry, Center for Neurobiology and Behavior, Philadelphia, Pennsylvania., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Boehm I; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany., Boni C; INSERM 1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France., Buehren K; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Aachen, Germany., Bulant J; Department of Pediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Burghardt R; Department of Child and Adolescent Psychiatry, Klinikum Frankfurt/Oder, Frankfurt, Germany., Chang X; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Cichon S; Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota.; The Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland.; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland., Cone RD; Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan., Courtet P; Department of Emergency Psychiatry and Post-Acute Care, CHRU Montpellier, University of Montpellier, Montpellier, France., Crow S; Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota.; The Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland.; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland., Crowley JJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Danner UN; Department of Clinical Psychology, Faculty of Social Sciences, University Utrecht, Utrecht, the Netherlands.; Altrecht Eating Disorders Rintveld, Zeist, the Netherlands., de Zwaan M; Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany., Dedoussis G; Department of Nutrition and Dietetics, Harokopio University, Athens, Greece., DeSocio JE; College of Nursing, Seattle University, Seattle, Washington., Dick DM; Department of Psychology, Commonwealth University, Richmond, Virginia.; College Behavioral and Emotional Health Institute, Commonwealth University, Richmond, Virginia.; Department of Human and Molecular Genetics, Commonwealth University, Richmond, Virginia., Dikeos D; First Department of Psychiatry, National and Kapodistrian University of Athens, Medical School, Eginition Hospital, Athens, Greece., Dina C; L'institut du thorax, INSERM, CNRS, UNIV Nantes, Nantes, France., Djurovic S; NORMENT Centre, Department of Clinical Science, University of Oslo, Oslo, Norway.; Department of Medical Genetics, University of Bergen, Bergen, Norway., Dmitrzak-Weglarz M; Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland., Docampo-Martinez E; Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, Barcelona, Spain., Duriez P; INSERM 1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France.; GHU Paris Psychiatrie et Neurosciences, CMME, Paris, France., Egberts K; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Centre for Mental Health, Würzburg, Germany., Ehrlich S; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany., Eriksson JG; Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Escaramís G; Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, Barcelona, Spain., Esko T; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Estivill X; Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, Barcelona, Spain.; Genomics and Disease, Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Barcelona, Spain., Farmer A; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Fernández-Aranda F; Department of Psychiatry, University Hospital Bellvitge-IDIBELL and CIBEROBN, Barcelona, Spain.; Department of Clinical Sciences, School of Medicine, University of Barcelona, Barcelona, Spain., Fichter MM; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany.; Schön Klinik Roseneck Affiliated With the Medical Faculty of the University of Munich, Prien, Germany., Föcker M; Department of Child and Adolescent Psychiatry, University Hospital Münster, Münster, Germany., Foretova L; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany., Forstner AJ; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany., Frei O; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Gallinger S; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia.; Department of Emergency Psychiatry and Post-Acute Care, CHRU Montpellier, University of Montpellier, Montpellier, France.; Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Giegling I; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Giuranna J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Gonidakis F; First Department of Psychiatry, National and Kapodistrian University of Athens, Medical School, Eginition Hospital, Athens, Greece., Gorwood P; INSERM 1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France.; CMME (GHU Paris Psychiatrie et Neurosciences), Hôpital Sainte Anne, Paris, France., Gratacòs M; Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, Barcelona, Spain., Guillaume S; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia.; Department of Emergency Psychiatry and Post-Acute Care, CHRU Montpellier, University of Montpellier, Montpellier, France.; Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Guo Y; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Hakonarson H; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Hauser J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Havdahl A; Nic Waals Institute, Lovisenberg Diaconal Hospitaland, Oslo, Norway.; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Hebebrand J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Helder SG; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; Zorg op Orde, Delft, the Netherlands., Herms S; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland., Herpertz-Dahlmann B; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Aachen, Germany., Herzog W; Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany., Hinney A; Nic Waals Institute, Lovisenberg Diaconal Hospitaland, Oslo, Norway.; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Hübel C; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Hudson JI; Biological Psychiatry Laboratory, McLean Hospital/Harvard Medical School, Boston, Massachusetts., Imgart H; Eating Disorders Unit, Parklandklinik, Bad Wildungen, Germany., Jamain S; Inserm U955, Institut Mondor de recherches Biomédicales, Laboratoire, Neuro-Psychiatrie Translationnelle, and Fédération Hospitalo-Universitaire de Précision Médecine en Addictologie et Psychiatrie, University Paris-Est-Créteil, Créteil, France., Janout V; Faculty of Health Sciences, Palacky University, Olomouc, Czech Republic., Jiménez-Murcia S; Department of Psychiatry, University Hospital Bellvitge-IDIBELL and CIBEROBN, Barcelona, Spain.; Department of Clinical Sciences, School of Medicine, University of Barcelona, Barcelona, Spain., Jones IR; National Centre for Mental Health, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, United Kingdom., Julià A; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Kalsi G; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Kaminská D; Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Kaprio J; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Karhunen L; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.; Institute of Public Health and Clinical Nutrition, Department of Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kas MJH; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, the Netherlands.; Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands., Keel PK; Department of Psychology, Florida State University, Tallahassee, Florida., Kennedy JL; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Keski-Rahkonen A; Clinicum, Department of Public Health, University of Helsinki, Helsinki, Finland., Kiezebrink K; Institute of Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom., Klareskog L; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.; Institute of Public Health and Clinical Nutrition, Department of Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Klump KL; Department of Psychology, Michigan State University, Lansing, Michigan., Knudsen GPS; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway., La Via MC; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Le Hellard S; Department of Clinical Science, K.G. Jebsen Centre for Psychosis Research, Norwegian Centre for Mental Disorders Research, University of Bergen, Bergen, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, Laboratory Building, Haukeland University Hospital, Bergen, Norway., Leboyer M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Institute of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden.; Inserm U955, Institut Mondor de recherches Biomédicales, Laboratoire, Neuro-Psychiatrie Translationnelle, and Fédération Hospitalo-Universitaire de Précision Médecine en Addictologie et Psychiatrie, University Paris-Est-Créteil, Créteil, France., Li D; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Lilenfeld L; Department of Clinical Psychology, the Chicago School of Professional Psychology, Washington, DC., Lin B; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, the Netherlands., Lissowska J; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, the Netherlands.; Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Luykx J; Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, the Netherlands.; Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Magistretti P; Department of Psychiatry, University of Lausanne-University Hospital of Lausanne, Lausanne, Switzerland.; BESE Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy., Maj M; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychiatry, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Marsal S; InsideOut Institute for Eating Disorders, The Charles Perkins Centre, the University of Sydney, Sydney, New South Wales, Australia.; Sydney Local Health District, NSW Health, St. Leonards, New South Wales, Australia.; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Marshall CR; Department of Paediatric Laboratory Medicine, the Hospital for Sick Children, Toronto, Ontario, Canada., Mattingsdal M; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychiatry, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Meulenbelt I; Department of Biomedical Data Science, Leiden University Medical Centre, Leiden, the Netherlands., Micali N; Department of Psychiatry, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Pediatrics Gynaecology and Obstetrics, University of Geneva, Geneva, Switzerland., Mitchell KS; Women's Health Sciences Division, National Center for PTSD, Boston, Massachusetts.; Department of Psychiatry, Boston University, Boston, Massachusetts., Monteleone AM; Department of Psychiatry, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Monteleone P; Department of Psychiatry, University of Lausanne-University Hospital of Lausanne, Lausanne, Switzerland.; BESE Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy., Myers R; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama., Navratilova M; Department of Cancer, Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic., Ntalla I; Department of Nutrition and Dietetics, Harokopio University, Athens, Greece., O'Toole JK; Kartini Clinic, Portland, Oregon., Ophoff RA; Center for Neurobehavioral Genetics, University of California at Los Angeles, Los Angeles, California.; Department of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Padyukov L; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden., Pantel J; INSERM 1124, Université de Paris, Paris, France., Papežová H; Eating Disorders Unit, Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Pinto D; Division of Psychiatric Genomics, Department of Psychiatry, and Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York., Raevuori A; Department of Adolescent Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Clinicum, Department of Public Health, University of Helsinki, Helsinki, Finland.; Department of Adolescent Psychiatry, University of Helsinki, Helsinki, Finland.; Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnologies, University of Pisa, Pisa, Italy., Ramoz N; INSERM 1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France., Reichborn-Kjennerud T; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway., Ricca V; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; Department of Health Science, University of Florence, Florence, Italy., Ripatti S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Department of Biometry, University of Helsinki, Helsinki, Finland., Ripke S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Department of Biometry, University of Helsinki, Helsinki, Finland., Ritschel F; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Eating Disorders Research and Treatment Center, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Roberts M; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Rotondo A; Clinicum, Department of Public Health, University of Helsinki, Helsinki, Finland.; Department of Adolescent Psychiatry, University of Helsinki, Helsinki, Finland.; Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnologies, University of Pisa, Pisa, Italy., Rujescu D; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Rybakowski F; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Eating Disorders Research and Treatment Center, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Scherag A; Institute of Medical Statistics, Computer and Data Sciences, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.; Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Scherer SW; McLaughlin Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Genetics and Genome Biology and the Center for Applied Genomics, the Hospital for Sick Children, Toronto, Ontario, Canada., Schmidt U; Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Scott LJ; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Seitz J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Aachen, Germany., Silén Y; Clinicum, Department of Public Health, University of Helsinki, Helsinki, Finland., Šlachtová L; Department of Biochemistry and Molecular Biology, Institute of Organic Chemistry and Biochemistry, Prague, Czech Republic., Slagboom PE; Department of Biomedical Data Science, Leiden University Medical Centre, Leiden, the Netherlands., Slof-Op 't Landt MCT; Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands.; Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands., Slopien A; Institute of Medical Statistics, Computer and Data Sciences, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.; Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Sorbi S; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; IRCSS Fondazione Don Carlo Gnocchi, Florence, Italy., Świątkowska B; Department of Environmental Epidemiology, the Reference Center for Asbestos Exposure and Health Risk Assessment, Lódź, Poland., Tortorella A; Adolescent Health Unit, Second Department of Pediatrics, Athens, Greece.; Department of Psychiatry, University of Perugia, Perugia, Italy., Tozzi F; Brain Sciences Department, Stremble Ventures, Limassol, Cyprus., Treasure J; Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Tsitsika A; Adolescent Health Unit, Second Department of Pediatrics, Athens, Greece.; Department of Psychiatry, University of Perugia, Perugia, Italy., Tyszkiewicz-Nwafor M; Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., Tziouvas K; Pediatric Intensive Care Unit, 'P. & A. Kyriakou' Children's Hospital, University of Athens, Athens, Greece., van Elburg AA; Department of Clinical Psychology, Faculty of Social Sciences, University Utrecht, Utrecht, the Netherlands.; Altrecht Eating Disorders Rintveld, Zeist, the Netherlands., van Furth EF; Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands.; Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands., Walton E; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, Helsinki, Finland., Widen E; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, Helsinki, Finland., Zerwas S; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tuebingen, Tuebingen, Germany.; Centre of Excellence for Eating Disorders, University Tuebingen, Tuebingen, Germany., Zipfel S; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tuebingen, Tuebingen, Germany.; Centre of Excellence for Eating Disorders, University Tuebingen, Tuebingen, Germany., Bergen AW; Oregon Research Institute, Eugene, Oregon.; Biorealm Research, Walnut, California., Boden JM; Department of Psychological Medicine, University of Otago, Christchurch, New Zealand., Brandt H; The Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland., Crawford S; Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota.; The Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland.; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland., Halmi KA; New York Presbyterian Hospital-Westchester Division, Weill Cornell Medical College of Cornell University, White Plains, New York., Horwood LJ; Department of Psychological Medicine, University of Otago, Christchurch, New Zealand., Johnson C; Eating Recovery Center, Denver, Colorado., Kaplan AS; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Kaye WH; Department of Psychiatry, University of California San Diego, San Diego, California., Mitchell JE; Department of Psychiatry and Behavioral Science, School of Medicine and Health Sciences, University of North Dakota, Fargo, North Dakota., Olsen CM; Cancer Control Group, University of Queensland, Brisbane, Queensland, Australia., Pearson JF; Biostatistics and Computational Biology Unit, University of Otago, Christchurch, New Zealand., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Strober M; Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California.; David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California., Werge T; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Whiteman DC; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia., Woodside DB; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Centre for Mental Health, University Health Network, Toronto, Ontario, Canada.; Program for Eating Disorders, University Health Network, Toronto, Ontario, Canada., Gordon S; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia.; Department of Emergency Psychiatry and Post-Acute Care, CHRU Montpellier, University of Montpellier, Montpellier, France.; Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Maguire S; InsideOut Institute for Eating Disorders, The Charles Perkins Centre, the University of Sydney, Sydney, New South Wales, Australia.; Sydney Local Health District, NSW Health, St. Leonards, New South Wales, Australia.; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Larsen JT; National Centre for Register-based Research, Aarhus BSS, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Parker R; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia., Petersen LV; National Centre for Register-based Research, Aarhus BSS, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Jordan J; Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.; Clinical Research Unit, Canterbury District Health Board, Christchurch, New Zealand., Kennedy M; Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Wade TD; College of Education, Psychology and Social Work, Flinders University, Adelaide, South Australia, Australia., Birgegård A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lichtenstein P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Landén M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Institute of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden.; Inserm U955, Institut Mondor de recherches Biomédicales, Laboratoire, Neuro-Psychiatrie Translationnelle, and Fédération Hospitalo-Universitaire de Précision Médecine en Addictologie et Psychiatrie, University Paris-Est-Créteil, Créteil, France., Martin NG; QIMR Berghofer Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia., Mortensen PB; National Centre for Register-based Research, Aarhus BSS, Aarhus, Denmark.; Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Breen G; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Bulik CM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Biological psychiatry global open science [Biol Psychiatry Glob Open Sci] 2021 Sep 20; Vol. 2 (4), pp. 368-378. Date of Electronic Publication: 2021 Sep 20 (Print Publication: 2022).

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Autor: Huckins LM; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.; Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hatzikotoulas K; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Southam L; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Thornton LM; Department of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Steinberg J; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Aguilera-McKay F; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Treasure J; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Schmidt U; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Gunasinghe C; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Romero A; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Curtis C; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Rhodes D; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Moens J; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Kalsi G; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Dempster D; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Leung R; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Keohane A; Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR BRC SLaM BioResource for Mental Health, SGDP Centre & Centre for Neuroimaging Sciences, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Burghardt R; Klinik für Kinder- und Jugendpsychiatrie, Psychotherapie und Psychosomatik Klinikum Frankfurt, Frankfurt, Germany., Ehrlich S; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany.; Eating Disorders Research and Treatment Center, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany., Hebebrand J; Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Hinney A; Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Ludolph A; Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Germany., Walton E; Division of Psychological & Social Medicine and Developmental Neurosciences, Technische Universität Dresden, Faculty of Medicine, University Hospital C.G. Carus, Dresden, Germany.; Department of Psychology, Georgia State University, Atlanta, GA, USA., Deloukas P; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Hofman A; Erasmus University Medical Center, Rotterdam, The Netherlands., Palotie A; Center for Human Genome Research at the Massachusetts General Hospital, Boston, MA, USA.; Department of Public Health & Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland., Palta P; Department of Public Health & Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland., van Rooij FJA; Erasmus University Medical Center, Rotterdam, The Netherlands., Stirrups K; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK., Adan R; Brain Center Rudolf Magnus, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands., Boni C; INSERM U984, Centre of Psychiatry and Neuroscience, Paris, France., Cone R; Mary Sue Coleman Director, Life Sciences Institute, Professor of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., van Furth E; Rivierduinen Eating Disorders Ursula, Leiden, Zuid-Holland, The Netherlands., Gonidakis F; Eating Disorders Unit, 1st Department of Psychiatry, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Gorwood P; INSERM U984, Centre of Psychiatry and Neuroscience, Paris, France., Hudson J; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA., Kaprio J; Department of Public Health & Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland., Kas M; Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, The Netherlands., Keski-Rahkonen A; Department of Public Health, Clinicum, University of Helsinki, Helsinki, Finland., Kiezebrink K; Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK., Knudsen GP; Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, Norway., Slof-Op 't Landt MCT; Rivierduinen Eating Disorders Ursula, Leiden, Zuid-Holland, The Netherlands., Maj M; Department of Psychiatry, University of Naples SUN, Naples, Italy., Monteleone AM; Department of Psychiatry, University of Naples SUN, Naples, Italy., Monteleone P; Department of Medicine and Surgery, Section of Neurosciences, University of Salerno, Salerno, Italy., Raevuori AH; Department of Public Health, Clinicum, University of Helsinki, Helsinki, Finland., Reichborn-Kjennerud T; Department of Genetics, Environment and Mental Health, Norwegian Institute of Public Health, Oslo, Norway., Tozzi F; eHealth Lab-Computer Science Department, University of Cyprus, Nicosia, Cyprus., Tsitsika A; Adolescent Health Unit (A.H.U.), 2nd Department of Pediatrics - Medical School, University of Athens 'P. & A. Kyriakou' Children's Hospital, Athens, Greece., van Elburg A; Center for Eating Disorders Rintveld, University of Utrecht, Utrecht, The Netherlands., Collier DA; Eli Lilly and Company, Erl Wood Manor, Windlesham, UK., Sullivan PF; Departments of Genetics and Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medical Epidemiology and Biostatistics, Karolinksa Institutet, Stockholm, Sweden., Breen G; Social Genetic and Developmental Psychiatry, King's College London, London, UK., Bulik CM; Department of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medical Epidemiology and Biostatistics, Karolinksa Institutet, Stockholm, Sweden., Zeggini E; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2018 May; Vol. 23 (5), pp. 1169-1180. Date of Electronic Publication: 2017 Jul 25.