Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Slobodan Paessler"'
Autor:
Kachollom C. Best, Emmanuel Ameh, Caroline Weldon, David Shwe, Ibrahim Mahmood Maigari, Ishaku Turaki, Nuhu D. Ma’an, Christopher Sabo Yilgwan, Tomoko Makishima, Scott Weaver, Slobodan Paessler, Nathan Y. Shehu
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionLassa fever is a zoonotic infectious disease endemic in West Africa with a high case-fatality rate and reported stigmatization of surviving patients. This study examines discrimination among survivors of Lassa fever (LF) complicated by he
Externí odkaz:
https://doaj.org/article/5987f7c5ec3c4a769d66bf5982d8925b
Autor:
Chanida Fongsaran, Krit Jirakanwisal, Bi-Hung Peng, Anna Fracassi, Giulio Taglialatela, Kelly T. Dineley, Slobodan Paessler, Irma E. Cisneros
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100780- (2024)
Alzheimer's disease is classified as a progressive disorder resulting from protein misfolding, also known as proteinopathies. Proteinopathies include synucleinopathies triggered by misfolded amyloid α-synuclein, tauopathies triggered by misfolded ta
Externí odkaz:
https://doaj.org/article/eb7b942bab794828a68940c2929b7389
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1185 (2024)
SARS-CoV-2, the pathogen causing COVID-19, continues to pose a significant threat to public health and has had major economic implications. Developing safe and effective vaccines and therapies offers a path forward for overcoming the COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/7ed385d5552344c9a741312033270491
Publikováno v:
Pathogens, Vol 13, Iss 5, p 397 (2024)
Neurodegenerative diseases are chronic conditions affecting the central nervous system (CNS). Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid beta in the limbic and cortical brain regions. AD is
Externí odkaz:
https://doaj.org/article/9ae9d267999d4311bd68c9ae0c03981a
Autor:
Vladimir Perovic, Kristina Stevanovic, Natalya Bukreyeva, Slobodan Paessler, Junki Maruyama, Sergi López-Serrano, Ayub Darji, Milan Sencanski, Draginja Radosevic, Simone Berardozzi, Bruno Botta, Mattia Mori, Sanja Glisic
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4911 (2024)
The influenza A virus nonstructural protein 1 (NS1), which is crucial for viral replication and immune evasion, has been identified as a significant drug target with substantial potential to contribute to the fight against influenza. The emergence of
Externí odkaz:
https://doaj.org/article/9eea7d0871e047f4a013bed4a1c970c9
Autor:
Rachel A. Reyna, Kirsten E. Littlefield, Nathan Shehu, Tomoko Makishima, Junki Maruyama, Slobodan Paessler
Publikováno v:
Viruses, Vol 16, Iss 2, p 266 (2024)
Lassa virus (LASV) is a zoonotic pathogen endemic throughout western Africa and is responsible for a human disease known as Lassa fever (LF). Historically, LASV has been emphasized as one of the greatest public health threats in West Africa, with up
Externí odkaz:
https://doaj.org/article/0eba0fa94bca4fe08943835468dcac3e
Autor:
Wenjing Yang, Tianming Yu, Guangxi Zhou, Suxia Yao, Maki Wakamiya, Haitao Hu, Slobodan Paessler, Jiaren Sun, Yingzi Cong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1161-1179 (2023)
Background & Aims: T helper 1 (Th1) effector cells are implicated in inflammatory bowel disease. The stimulator of interferon genes (STING), an intracellular DNA sensor, has been shown to regulate infection and various cancers. However, whether and h
Externí odkaz:
https://doaj.org/article/7fa63b1e93ab47019179ffdd17d0a64c
Autor:
Yue Qu, Aline Haas de Mello, Dorothea R. Morris, Yava L. Jones-Hall, Teodora Ivanciuc, Rachel A. Sattler, Slobodan Paessler, Vineet D. Menachery, Roberto P. Garofalo, Antonella Casola
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Several viruses have been shown to modulate the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible
Externí odkaz:
https://doaj.org/article/5ea4d81b9cda4a46921942078da9c6cc
Autor:
John Tyler Manning, Junki Maruyama, Timothy Wanninger, Rachel A. Reyna, Heather L. Stevenson, Bi-Hung Peng, Emily K. Mantlo, Cheng Huang, Slobodan Paessler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Junin virus (JUNV) is a member of the Arenaviridae family of viruses and is the pathogen responsible for causing Argentine hemorrhagic fever, a potentially lethal disease endemic to Argentina. A live attenuated vaccine for human use, called Candid#1,
Externí odkaz:
https://doaj.org/article/2d710306a8a443ac96bf8436d9e66e77
Autor:
Xia Cao, Junki Maruyama, Heyue Zhou, Yanwen Fu, Lisa Kerwin, Colin Powers, Rachel A. Sattler, John T. Manning, Alok Singh, Reyna Lim, Laura D. Healy, Sachi Johnson, Elizabeth Paz Cabral, Donghui Li, Lucy Lu, Arthur Ledesma, Daniel Lee, Susan Richards, Laura Rivero-Nava, Yan Li, Weiqun Shen, Karen Stegman, Benjamin Blair, Shinji Urata, Magumi Kishimoto-Urata, Jamie Ko, Na Du, Kyndal Morais, Kate Lawrence, Ianne Rivera, Chin-I. Pai, Damien Bresson, Mark Brunswick, Yanliang Zhang, Henry Ji, Slobodan Paessler, Robert D. Allen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Coronavirus disease 2019 (COVID-19) continues to significantly impact the global population, thus countermeasure platforms that enable rapid development of therapeutics against variants of SARS-CoV-2 are essential. We report use of a phage d
Externí odkaz:
https://doaj.org/article/37fca7f29c8b45c4a5a9a070e9d4f804