Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Slo1"'
Autor:
Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Monika Zochowska, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Ying Zhang, Irina Bonzheim, Florian A Büttner, Falko Fend, Matthias Schwab, Andreas L Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski
Publikováno v:
eLife, Vol 12 (2024)
Alterations in the function of K+ channels such as the voltage- and Ca2+-activated K+ channel of large conductance (BKCa) reportedly promote breast cancer (BC) development and progression. Underlying molecular mechanisms remain, however, elusive. Her
Externí odkaz:
https://doaj.org/article/60f91b8d7664470fa1f56e117e4caef3
Autor:
Chao Xia, Yonghui Wang, Tianyuan Jiang, Yan Hu, Yang Chen, Xinrun Ma, Xuemei Zhang, Yanhong Gao
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1737-1752 (2023)
Abstract Background It has been observed that Slo1 knockout mice have reduced motor function, and people with certain Slo1 mutations have movement problems, but there is no answer whether the movement disorder is caused by the loss of Slo1 in the ner
Externí odkaz:
https://doaj.org/article/8eabf90ad9e143a2aed3d016dff35c92
Autor:
Koichi Nakajo, Go Kasuya
Publikováno v:
Physiological Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Voltage‐gated K+ (KV) and Ca2+‐activated K+ (KCa) channels are essential proteins for membrane repolarization in excitable cells. They also play important physiological roles in non‐excitable cells. Their diverse physiological function
Externí odkaz:
https://doaj.org/article/738bd6faee7d470c8afa8df4a2cd1573
Autor:
Dragos Paul Mihai, Rica Boscencu, Gina Manda, Andreea Mihaela Burloiu, Georgiana Vasiliu, Ionela Victoria Neagoe, Radu Petre Socoteanu, Dumitru Lupuliasa
Publikováno v:
Molecules, Vol 28, Iss 4, p 1640 (2023)
The aim of the present study was to assess the effects exerted in vitro by three asymmetrical porphyrins (5-(2-hydroxyphenyl)-10,15,20-tris-(4-acetoxy-3-methoxyphenyl)porphyrin, 5-(2-hydroxyphenyl)-10,15,20-tris-(4-acetoxy-3-methoxyphenyl)porphyrinat
Externí odkaz:
https://doaj.org/article/fd72d4afef974390b1be4d6d0b8083f1
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
BK channels are composed by the pore forming α subunit and, in some tissues, is associated with different accessory β subunits. These proteins modify the biophysical properties of the channel, amplifying the range of BK channel activation according
Externí odkaz:
https://doaj.org/article/a7bba147d0a346efb2b5188f8e3876ea
Autor:
Xiao Tao, Roderick MacKinnon
Publikováno v:
eLife, Vol 8 (2019)
Slo1 is a Ca2+- and voltage-activated K+ channel that underlies skeletal and smooth muscle contraction, audition, hormone secretion and neurotransmitter release. In mammals, Slo1 is regulated by auxiliary proteins that confer tissue-specific gating a
Externí odkaz:
https://doaj.org/article/4ad26397faf64b9ba00cd134e10ad719
Autor:
Yang, Chengtao, Gonzalez-Perez, Vivian, Mukaibo, Taro, Melvin, James E., Xia, Xiao-Ming, Lingle, Christopher J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 May 01. 114(18), E3739-E3747.
Externí odkaz:
https://www.jstor.org/stable/26481902
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Dec 01. 113(49), 14055-14060.
Externí odkaz:
https://www.jstor.org/stable/26472769