Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Series of Bis-1,2,4-Triazoles as Thymidine Phosphorylase Inhibitor

Autor: Korol N, Holovko-Kamoshenkova OM, Slivka M, Pallah O, Onysko MY, Kryvovyaz A, Boyko NV, Yaremko OV, Mariychuk R

Publikováno v: Advances and Applications in Bioinformatics and Chemistry, Vol Volume 16, Pp 93-102 (2023)

Nataliya Korol,1 Oksana M Holovko-Kamoshenkova,1 Mikhailo Slivka,1 Oleksandra Pallah,2 Mykhailo Yu Onysko,1 Andriy Kryvovyaz,1 Nadiya V Boyko,2 Olha V Yaremko,3 Ruslan Mariychuk4 1Organic Chemistry Department, Educational and Research Institute of Ch

Externí odkaz: https://doaj.org/article/bcb976922ef6411a9943ef833b321831

REGIOSELECTIVITY OF ALKYLATION REACTION OF 2-OXO-(THIO)-3-PHENYL-THIENO[2,3-d]PYRIMIDINONES

Autor: Slivka, M. V., Onysko, M. Yu., Korol, N. I., Fizer, M. M., Lendel, V. G.

Publikováno v: Науковий вісник Ужгородського університету. Серія "Хімія"; Том 2, № 44 (2020); 69-76
Scientific Bulletin of the Uzhhorod University. Series «Chemistry»; Том 2, № 44 (2020); 69-76

The elaboration of easy and affordable highly selective methods for the synthesis of thieno[2,3-d]pyrimidine derivatives, which operate on none toxic reagents and energy-saving techniques, is an urgent task of organic chemistry. Among the large numbe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=scientific_p::28566650a738d18aeb09da03e8506467
http://visnyk-khim.uzhnu.edu.ua/article/view/220639

THEORETICAL INVESTIGATION OF THE INFLUENCE OF AMINO AND MERCAPTO GROUPS ON AROMATICITY OF THE 1,2,4-TRIAZOLE

Autor: Fizer, M. M., Fizer, O. I., Slivka, M. V., Lendel, V. G.

Publikováno v: Науковий вісник Ужгородського університету. Серія "Хімія"; Том 1, № 43 (2020); 53-60
Scientific Bulletin of the Uzhhorod University. Series «Chemistry»; Том 1, № 43 (2020); 53-60

The work is devoted to the theoretical study of the effect of the introduction of mercapto and amino groups on the aromaticity of 1,2,4-triazole cycle. Aromaticity is one of the key concepts in modern organic chemistry, and the question of the aromat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=scientific_p::96c7287c1fda9c9a191a82de7f750d86
http://visnyk-khim.uzhnu.edu.ua/article/view/206025

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