Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Slim Karkar"'
Autor:
Julien Van Gils, Slim Karkar, Aurélien Barre, Seyta Ley-Ngardigal, Sophie Nothof, Stéphane Claverol, Caroline Tokarski, Jean-Philippe Trani, Raphael Chevalier, Natacha Broucqsault, Claire El Yazidi, Didier Lacombe, Patricia Fergelot, Frédérique Magdinier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Rubinstein-Taybi syndrome (RTS) is a rare and severe genetic developmental disorder characterized by multiple congenital anomalies and intellectual disability. CREBBP and EP300, the two genes known to cause RTS encode transcriptional coactiv
Externí odkaz:
https://doaj.org/article/5ca15b01bb7840f3b1cb9bd06d1fa239
Autor:
Joris Guyon, Ignacio Fernandez‐Moncada, Claire M Larrieu, Cyrielle L Bouchez, Antonio C Pagano Zottola, Johanna Galvis, Tiffanie Chouleur, Audrey Burban, Kevin Joseph, Vidhya M Ravi, Heidi Espedal, Gro Vatne Røsland, Boutaina Daher, Aurélien Barre, Benjamin Dartigues, Slim Karkar, Justine Rudewicz, Irati Romero‐Garmendia, Barbara Klink, Konrad Grützmann, Marie‐Alix Derieppe, Thibaut Molinié, Nina Obad, Céline Léon, Giorgio Seano, Hrvoje Miletic, Dieter Henrik Heiland, Giovanni Marsicano, Macha Nikolski, Rolf Bjerkvig, Andreas Bikfalvi, Thomas Daubon
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp n/a-n/a (2022)
Abstract Lactate is a central metabolite in brain physiology but also contributes to tumor development. Glioblastoma (GB) is the most common and malignant primary brain tumor in adults, recognized by angiogenic and invasive growth, in addition to its
Externí odkaz:
https://doaj.org/article/ba568585186d48d99efb5ec52859e399
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S16, Pp 1-12 (2019)
Abstract Background In order to isolate an individual’s genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repea
Externí odkaz:
https://doaj.org/article/0bafb71ed85b4be99c99378533ed4bc8
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Yann Le Guen, Cathy Philippe, Edith Le Floch, Jean-François Mangin, Morgane Pierre-Jean, Vincent Frouin, Jean-François Deleuze, Claire Dandine-Roulland, Slim Karkar
Publikováno v:
European Journal of Human Genetics
Neuroimaging-genetics cohorts gather two types of data: brain imaging and genetic data. They allow the discovery of associations between genetic variants and brain imaging features. They are invaluable resources to study the influence of genetics and
Autor:
Lauren E. Alfonse, Slim Karkar, Catherine M. Grgicak, Ken R. Duffy, Desmond S. Lun, Xia Yearwood-Garcia
Forensic DNA signal is notoriously challenging to interpret and requires the implementation of computational tools that support its interpretation. While data from high-copy, low-contributor samples result in electropherogram signal that is readily i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bdcacdb2f70905d3ec181f548ac605
https://mural.maynoothuniversity.ie/15202/
https://mural.maynoothuniversity.ie/15202/
Autor:
Andrew K, Watson, Romain, Lannes, Jananan S, Pathmanathan, Raphaël, Méheust, Slim, Karkar, Philippe, Colson, Eduardo, Corel, Philippe, Lopez, Eric, Bapteste
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1910
In the post genomic era, large and complex molecular datasets from genome and metagenome sequencing projects expand the limits of what is possible for bioinformatic analyses. Network-based methods are increasingly used to complement phylogenetic anal
Autor:
Eric Bapteste, Slim Karkar, Andrew K Watson, Jananan S. Pathmanathan, Philippe Lopez, Raphaël Méheust, Philippe Colson, Eduardo Corel, Romain Lannes
Publikováno v:
Evolutionary Genomics
Evolutionary Genomics, pp.271-308, 2019, ⟨10.1007/978-1-4939-9074-0_9⟩
Evolutionary Genomics, Statistical and Computational Methods
Evolutionary Genomics, Statistical and Computational Methods, pp.271-308, 2019
Methods in Molecular Biology ISBN: 9781493990733
Evolutionary Genomics, pp.271-308, 2019, ⟨10.1007/978-1-4939-9074-0_9⟩
Evolutionary Genomics, Statistical and Computational Methods
Evolutionary Genomics, Statistical and Computational Methods, pp.271-308, 2019
Methods in Molecular Biology ISBN: 9781493990733
International audience; In the post genomic era, large and complex molecular datasets from genome and metagenome sequencing projects expand the limits of what is possible for bioinformatic analyses. Network-based methods are increasingly used to comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9f00296c267944530e7160a69d8cce
https://hal.science/hal-02324786
https://hal.science/hal-02324786
Autor:
A. Gloaguen, Slim Karkar, Cathy Philippe, Nicolas Guigui, Vincent Guillemot, Vincent Frouin, Tommy Löfstedt
Publikováno v:
ISBI 2019-Proceedings of the IEEE International Symposium on Biomedical Imaging
ISBI 2019-Proceedings of the IEEE International Symposium on Biomedical Imaging, Apr 2019, Venice, Italy. ⟨10.1109/ISBI.2019.8759593⟩
ISBI
ISBI 2019-Proceedings of the IEEE International Symposium on Biomedical Imaging, Apr 2019, Venice, Italy. ⟨10.1109/ISBI.2019.8759593⟩
ISBI
International audience; Imaging-genetics is a growing popular research avenue which aims to find genetic variants associated with quantitative phenotypes that characterize a disease. In this work, we combine structural MRI with genetic data structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3031e915e217c405054b917608d9f8d
https://cea.hal.science/cea-02016625/document
https://cea.hal.science/cea-02016625/document
Autor:
Arnaud Gloaguen, Cathy Philippe, Vincent Frouin, Arthur Tenenhaus, Morgane Pierre-Jean, E. Le Floc'h, Y. Le Guen, Claire Dandine-Roulland, Slim Karkar
Publikováno v:
ISBI
Imaging genetic studies of large control cohorts such as UK Biobank enable to assess the range of normal variations in brain structures. Previous studies by our group have shown that the width of several cortical sulci is associated with a variant in