Zobrazeno 1 - 10
of 3 779
pro vyhledávání: '"Slice preparation"'
Autor:
Phillip Rieder, Davide Gobbo, Gebhard Stopper, Anna Welle, Elisa Damo, Frank Kirchhoff, Anja Scheller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The spinal cord is the main pathway connecting brain and peripheral nervous system. Its functionality relies on the orchestrated activity of both neurons and glial cells. To date, most advancement in understanding the spinal cord inner mechanisms has
Externí odkaz:
https://doaj.org/article/925231cb54d14bd9913dcaac507ac694
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Voltage imaging with cellular resolution in mammalian brain slices is still a challenging task. Here, we describe and validate a method for delivery of the voltage-sensitive dye ANNINE-6plus (A6+) into tissue for voltage imaging that results in highe
Externí odkaz:
https://doaj.org/article/df6159724dc04e338ba9c44d3f81ec94
Publikováno v:
Neuroscience. 478:89-99
We previously observed in rodents that during the 2nd postnatal week corticospinal axons make monosynaptic connections with motoneurons. Prior to that finding, it had been believed that such contacts only occur in higher primates. Although an in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c8dac3256f600cfe07c33bf9f083ef
https://doi.org/10.1016/j.neuroscience.2021.09.006
https://doi.org/10.1016/j.neuroscience.2021.09.006
Autor:
Jeremiah P. Hartner, Laura A. Schrader
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Spatial memory processing requires functional interaction between the hippocampus and the medial entorhinal cortex (MEC). The grid cells of the MEC are most abundant in layer II and rely on a complex network of local inhibitory interneurons to genera
Externí odkaz:
https://doaj.org/article/6454d986a01344fc802d0ddb93e2bc94
Autor:
Yasuhiko Saito, Masayuki Kobayashi, Tetsuo Shirakawa, Yuchio Yanagawa, Yuka Nakaya, Kiyofumi Yamamoto, Kensuke Hirose, Kohei Kitano, Ryosuke Kaneko
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:1911-1924
The nucleus accumbens (NAc) receives cortical projections principally from the insular cortex (IC) and medial prefrontal cortex (mPFC). Among NAc neurons, cholinergic interneurons (ChNs) regulate the activities of medium spiny neurons (MSNs), which m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda8886d72113cc08767b7745d5ba7f1
https://doi.org/10.1007/s00424-021-02634-y
https://doi.org/10.1007/s00424-021-02634-y
Autor:
Andrew P. Carlson, Kevin C. Brennan, Alanna Humphrey, C. William Shuttleworth, Katelyn M. Reinhart
Publikováno v:
Neurocrit Care
Spreading depolarization (SD) has been identified as a key mediator of secondary lesion progression after acute brain injuries, and clinical studies are beginning to pharmacologically target SDs. Although initial work has focused on the N-Methyl-D-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b699a5e2fdcc2508fd1650ae4c8e6000
https://doi.org/10.1007/s12028-021-01351-9
https://doi.org/10.1007/s12028-021-01351-9
Autor:
Claudia Benkwitz, Robert A. Pearce, Alexander G Figueroa, Nicholas A. Kunz, Gregg E. Homanics, Gabe Surges
Publikováno v:
Journal of Neurophysiology. 126:1090-1100
Etomidate exerts its anesthetic actions through GABAA receptors. However, the mechanism remains unknown. Here, using a hippocampal brain slice model, we show that β2-GABAARs are essential to this effect. We also show that these receptors contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2add66b0ec3bb8b70b5ceee372f1a8ec
https://doi.org/10.1152/jn.00303.2021
https://doi.org/10.1152/jn.00303.2021
Autor:
Kiarash Shamardani, Hillel Adesnik, Ashley K. Nensel, Kayli N. Martinez, Gloria Ortiz, Evan W. Miller, Pei Liu, Parker E. Deal
Publikováno v:
RSC Chemical Biology
We describe the design, synthesis, and application of voltage-sensitive silicon rhodamines. Based on the Berkeley Red Sensor of Transmembrane potential, or BeRST, scaffold, the new dyes possess an isomeric molecular wire for improved alignment in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd19d07204ae124b89cb703909286e6e
http://europepmc.org/articles/PMC8637932
http://europepmc.org/articles/PMC8637932
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Alcohol excites neurons of the ventral tegmental area (VTA) and the release of dopamine from these neurons is a key event in ethanol (EtOH)-induced reward and reinforcement. Many mechanisms have been proposed to explain EtOH's actions on n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974d7d6df24ad9c54fb4119aa94a9ef8
https://doi.org/10.1111/acer.14630
https://doi.org/10.1111/acer.14630
Autor:
Isamu Aiba, Jeffrey L. Noebels
Publikováno v:
Brain
Spreading depolarization is a slowly propagating wave of massive cellular depolarization associated with acute brain injury and migraine aura. Genetic studies link depolarizing molecular defects in Ca2+ flux, Na+ current in interneurons, and glial Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053964d2f1d7bdb2bb7490ecc0f835ff
https://doi.org/10.1093/brain/awab141
https://doi.org/10.1093/brain/awab141