Positron emission tomography neuroimaging of [¹⁸F]fluorodeoxyglucose uptake and related behavior in the Pink1-/- rat model of Parkinson disease.

Autor: Converse, Alexander K., Krasko, Maryann N., Rudisch, Denis Michael, Lunaris, Charlie Lenell, Nisbet, Alex F., Slesarev, Maxim S., Szot, John C., Hoerst, Andrew G., Leverson, Glen E., Gallagher, Catherine L., Ciucci, Michelle R.

Publikováno v: Frontiers in Neuroscience; 2024, p1-26, 18p

Measuring α4β2* nicotinic acetylcholine receptor density in vivo with [(18)F]nifene PET in the nonhuman primate

Autor: Hillmer, Ansel T, Wooten, Dustin W, Slesarev, Maxim S, Ahlers, Elizabeth O, Barnhart, Todd E, Schneider, Mary L, Mukherjee, Jogeshwar, Christian, Bradley T

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 33, iss 11

[(18)F]Nifene is an agonist PET radioligand developed to image α4β2* nicotinic acetylcholine receptors (nAChRs). This work aims to quantify the receptor density (Bmax) of α4β2* nAChRs and the in vivo (apparent) dissociation constant (KDapp) of [(

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https://escholarship.org/uc/item/0550c036

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PET Imaging of α4β2* Nicotinic Acetyicholine Receptors: Quantitative Analysis of ¹⁸F-Nifene Kinetics in the Nonhuman Primate.

Autor: Hillmer, Ansel T., Wooten, Dustin W., Slesarev, Maxim S., Ahlers, Elizabeth O., Barnhart, Todd E., Murali, Dhanabalan, Schneider, Mary L., Mukherjee, Jogeshwar, Christian, Bradley T.

Publikováno v: Journal of Nuclear Medicine; 9/1/2012, Vol. 53 Issue 9, p1471-1480, 10p, 2 Color Photographs, 2 Charts, 5 Graphs

Positron emission tomography neuroimaging of [ ¹⁸ F]fluorodeoxyglucose uptake and related behavior in the Pink1 -/- rat model of Parkinson disease.

Autor: Converse AK; Waisman Center, University of Wisconsin-Madison, Madison, WI, United States., Krasko MN; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States.; Department of Communication Science and Disorders, University of Wisconsin-Madison, Madison, WI, United States., Rudisch DM; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States.; Department of Communication Science and Disorders, University of Wisconsin-Madison, Madison, WI, United States.; Institute for Clinical and Translational Research, University of Wisconsin-Madison, Madison, WI, United States., Lunaris CL; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States., Nisbet AF; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States., Slesarev MS; Waisman Center, University of Wisconsin-Madison, Madison, WI, United States., Szot JC; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States., Hoerst AG; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States., Leverson GE; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States., Gallagher CL; Department of Neurology, University of Wisconsin-Madison, Madison, WI, United States., Ciucci MR; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, WI, United States.; Department of Communication Science and Disorders, University of Wisconsin-Madison, Madison, WI, United States.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2024 Oct 15; Vol. 18, pp. 1451118. Date of Electronic Publication: 2024 Oct 15 (Print Publication: 2024).