Zobrazeno 1 - 10
of 1 237
pro vyhledávání: '"Slemmon"'
Autor:
Gallen Triana-Baltzer, Maarten Timmers, Peter De Boer, Manja Schoene, Maura Furey, Cathy Bleys, Isabeau Vrancken, Randy Slemmon, Marc Ceusters, Luc van Nueten, Hartmuth Kolb
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 10, Iss , Pp 100116- (2022)
Identification of putative biomarkers for neuropsychiatric disorders has produced a diverse list of analytes involved in inflammation, hypothalamic–pituitary–adrenal axis (HPA) regulation, growth factor and metabolic pathways. However, translatio
Externí odkaz:
https://doaj.org/article/f4be229663064b649cc97b1d83654ab8
Autor:
Shorena Janelidze, Erik Stomrud, Ruben Smith, Sebastian Palmqvist, Niklas Mattsson, David C. Airey, Nicholas K. Proctor, Xiyun Chai, Sergey Shcherbinin, John R. Sims, Gallen Triana-Baltzer, Clara Theunis, Randy Slemmon, Marc Mercken, Hartmuth Kolb, Jeffrey L. Dage, Oskar Hansson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cerebrospinal fluid (CSF) p-tau181 (tau phosphorylated at threonine 181) is an established biomarker of Alzheimer’s disease (AD) reflecting abnormal tau metabolism in the AD brain. Here the authors demonstrate that CSF p-tau217 shows better perform
Externí odkaz:
https://doaj.org/article/e021f91d669745fe90cd9b4d834f6303
Autor:
Feizpour, A., Doré, V., Doecke, J. D., Saad, Z. S., Triana-Baltzer, G., Slemmon, R., Maruff, P., Krishnadas, N., Bourgeat, P., Huang, K., Fowler, C., Rainey-Smith, S. R., Bush, A. I., Ward, L., Robertson, J., Martins, R. N., Masters, C. L., Villemagne, V. L., Fripp, J., Kolb, H. C.
Publikováno v:
Journal of Prevention of Alzheimer's Disease; Nov2023, Vol. 10 Issue 4, p828-836, 9p
Autor:
Gallen Triana‐Baltzer, Setareh Moughadam, Randy Slemmon, Kristof Van Kolen, Clara Theunis, Marc Mercken, Hartmuth C. Kolb
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Diagnosis of Alzheimer's disease (AD) based on amyloid beta (A), pathologic tau (T), and neurodegeneration (N) biomarkers in peripheral fluids promises to accelerate clinical trials and intercept disease earlier. Methods Qualifi
Externí odkaz:
https://doaj.org/article/af870e1028d04c88b91f60d009e68c2c
Autor:
Timmers, Maarten, Van Broeck, Bianca, Ramael, Steven, Slemmon, John, De Waepenaert, Katja, Russu, Alberto, Bogert, Jennifer, Stieltjes, Hans, Shaw, Leslie M., Engelborghs, Sebastiaan, Moechars, Dieder, Mercken, Marc, Liu, Enchi, Sinha, Vikash, Kemp, John, Van Nueten, Luc, Tritsmans, Luc, Streffer, Johannes Rolf
Publikováno v:
In Alzheimer's & Dementia: Translational Research & Clinical Interventions September 2016 2(3):202-212
Autor:
Tuomas Rauramaa, Darrel J. Pemberton, Maarten Timmers, Mikko Hiltunen, Hartmuth C. Kolb, Antti Junkkari, Peter van der Ark, Heikki Lukkarinen, Ville E. Korhonen, Johannes Streffer, Ville Leinonen, Sebastiaan Engelborghs, Anne M Koivisto, Henrik Zetterberg, Sanna-Kaisa Herukka, Luc Janssens, Ina Tesseur, Astrid Bottelbergs, Kaj Blennow, Luc Van Nueten, Randy Slemmon
Publikováno v:
Journal of Alzheimer's disease
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease
Background: Longitudinal changes in cerebrospinal fluid (CSF) biomarkers are seldom studied. Furthermore, data on biomarker gradient between lumbar (L-) and ventricular (V-) compartments seems to be discordant. Objective: To examine alteration of CSF
Autor:
Tong, Gary, Wang, Jun-Sheng, Sverdlov, Oleksandr, Huang, Shu-Pang, Slemmon, Randy, Croop, Robert, Castaneda, Lorna, Gu, Huidong, Wong, Oi, Li, Hewei, Berman, Robert M., Smith, Christina, Albright, Charles F., Dockens, Randy C.
Publikováno v:
In Clinical Therapeutics March 2012 34(3):654-667
Autor:
Thomas J. Malia, Marc Vandermeeren, Hong Sun, Kristof Van Kolen, Marc Mercken, Rupesh Nanjunda, Gallen Triana-Baltzer, M. Borgers, Astrid Bottelbergs, Eilyn R. Lacy, Alexey Teplyakov, Tom Van De Casteele, John Q. Trojanowski, Clara Theunis, Hervé Maurin, Peter Larsen, Robin Ernst, Sheng-Jiun Wu, Cindy Wintmolders, Roland Willems, Randy Slemmon, Wendy Galpern, Jinquan Luo
Publikováno v:
Journal of Alzheimer's Disease. 77:1397-1416
Background: As a consequence of the discovery of an extracellular component responsible for the progression of tau pathology, tau immunotherapy is being extensively explored in both preclinical and clinical studies as a disease modifying strategy for
Autor:
Hartmuth C. Kolb, Hong Sun, Kristof Van Kolen, Setareh Moughadam, Wendy Galpern, Clara Theunis, Marc Mercken, Randy Slemmon, Gallen Triana-Baltzer
Publikováno v:
Journal of Alzheimer's Disease
Background: Early and accurate detection and staging is critical to managing Alzheimer’s disease (AD) and supporting clinical trials. Cerebrospinal fluid (CSF) biomarkers for amyloid-β peptides, tau species, and various neurodegenerative and infla
Autor:
Vincent Doré, James D. Doecke, Ziad S. Saad, Gallen Triana‐Baltzer, Randy Slemmon, Natasha Krishnadas, Pierrick Bourgeat, Kun Huang, Samantha Burnham, Christopher Fowler, Stephanie R. Rainey‐Smith, Ashley I. Bush, Larry Ward, Jo Robertson, Ralph N. Martins, Colin L. Masters, Victor L. Villemagne, Jurgen Fripp, Hartmuth C. Kolb, Christopher C. Rowe
Publikováno v:
Alzheimer'sdementia (Amsterdam, Netherlands). 14(1)
We evaluated a new Simoa plasma assay for phosphorylated tau (P-tau) at aa217 enhanced by additional p-tau sites (p217+tau).Plasma p217+tau levels were compared toCompared to Aβ- CU, the plasma levels of p217+tau increased 2-fold in Aβ+ CU and 3.5-