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pro vyhledávání: '"Sleiman BouFakhreddine"'
Autor:
Thomas V. Holohan, Christopher J. Horvath, Tia DeFeo-Fraulini, H. Nicholas Marsh, Robert G. Schaub, Sleiman BouFakhreddine, James C. Gilbert, Judith M. Healy, Renta Hutabarat, Patricia G. Merlino
Publikováno v:
Circulation. 116:2678-2686
Background— ARC1779 is a therapeutic aptamer antagonist of the A1 domain of von Willebrand Factor (vWF), the ligand for receptor glycoprotein 1b on platelets. ARC1779 is being developed as a novel antithrombotic agent for use in patients with acute