Zobrazeno 1 - 10
of 9 623
pro vyhledávání: '"Sleigh, A"'
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111158- (2024)
Summary: Efficient long-range axonal transport is essential for maintaining neuronal function, and perturbations in this process underlie severe neurological diseases. Nodes of Ranvier (NoR) are short, specialized unmyelinated axonal domains with a u
Externí odkaz:
https://doaj.org/article/1528170810e44ac7b7cf79d7b3ada18a
Autor:
Sleigh, James N.1,2 (AUTHOR), Mattedi, Francesca3 (AUTHOR), Richter, Sandy3 (AUTHOR), Annuario, Emily3 (AUTHOR), Ng, Kristal3 (AUTHOR), Steinmark, I. Emilie4 (AUTHOR), Ivanova, Iveta4 (AUTHOR), Darabán, István L.3 (AUTHOR), Joshi, Parth P.3 (AUTHOR), Rhymes, Elena R.1,2 (AUTHOR), Awale, Shirwa4 (AUTHOR), Yahioglu, Gokhan5 (AUTHOR), Mitchell, Jacqueline C.3 (AUTHOR), Suhling, Klaus4 (AUTHOR), Schiavo, Giampietro1,2 (AUTHOR), Vagnoni, Alessio3,6 (AUTHOR) alessio.vagnoni@kcl.ac.uk
Publikováno v:
Aging Cell. Oct2024, Vol. 23 Issue 10, p1-20. 20p.
Autor:
Elena R. Rhymes, Rebecca L. Simkin, Ji Qu, David Villarroel-Campos, Sunaina Surana, Yao Tong, Ryan Shapiro, Robert W. Burgess, Xiang-Lei Yang, Giampietro Schiavo, James N. Sleigh
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106501- (2024)
Charcot-Marie-Tooth disease (CMT) is a genetic peripheral neuropathy caused by mutations in many functionally diverse genes. The aminoacyl-tRNA synthetase (ARS) enzymes, which transfer amino acids to partner tRNAs for protein synthesis, represent the
Externí odkaz:
https://doaj.org/article/6a2c5beddc18443097b6a65f58d65c80
Autor:
Sleigh, Duncan, Vermeeren, Mats
Publikováno v:
J. Phys. A: Math. Theor. 55 (2022) 475204
We present a variational theory of integrable differential-difference equations (semi-discrete integrable systems). This is a natural extension of the ideas known by the names "Lagrangian multiforms" and "Pluri-Lagrangian systems", which have previou
Externí odkaz:
http://arxiv.org/abs/2204.13063
We describe a variational framework for non-commuting flows, extending the theories of Lagrangian multiforms and pluri-Lagrangian systems, which have gained prominence in recent years as a variational description of integrable systems in the sense of
Externí odkaz:
http://arxiv.org/abs/2204.09663
Autor:
Tosolini, Andrew P., Abatecola, Federico, Negro, Samuele, Sleigh, James N., Schiavo, Giampietro
Publikováno v:
In iScience 15 November 2024 27(11)
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract In the age of Machine Learning Algorithms, Artificial Intelligence and Natural Language Processing, digital technologies have become interwoven in various aspects of society, including in our practices for ethical deliberation and decision-m
Externí odkaz:
https://doaj.org/article/a4a1c5d00101482696eaf548f4790a7f
Autor:
Rhymes, Elena R., Simkin, Rebecca L., Qu, Ji, Villarroel-Campos, David, Surana, Sunaina, Tong, Yao, Shapiro, Ryan, Burgess, Robert W., Yang, Xiang-Lei, Schiavo, Giampietro, Sleigh, James N.
Publikováno v:
In Neurobiology of Disease 1 June 2024 195
We define a conformally invariant action S on gauge connections on a closed pseudo-Riemannian manifold M of dimension 6. At leading order this is quadratic in the gauge connection. The Euler-Lagrange equations of S, with respect to variation of the g
Externí odkaz:
http://arxiv.org/abs/2107.08515
Publikováno v:
Journal of the American Medical Informatics Association ocab096 (2021)
Our scoping review aims to assess what legal, ethical, and socio-technical factors contribute or inhibit the success of national eHealth system implementations. In addition, our review seeks to describe the characteristics and benefits of eHealth sys
Externí odkaz:
http://arxiv.org/abs/2106.08737