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CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages

Autor: Evren, Elza, Ringqvist, Emma, Doisne, Jean-Marc, Thaller, Anna, Sleiers, Natalie, Flavell, Richard, Di Santo, James, Willinger, Tim

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, 2022, 219 (2), pp.e20210987. ⟨10.1084/jem.20210987⟩

Evren et al. identify CD116+ fetal liver cells as precursors of human alveolar macrophages in early life and determine the impact of cell origin on lung macrophage identity and function in the human context with a unique in vivo model.
Despite t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c3d7ca7ac6afa2740d844509edd9b8f2
https://pubmed.ncbi.nlm.nih.gov/35019940

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Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation

Autor: Emgård, Johanna, Kammoun, Hana, García-Cassani, Bethania, Chesné, Julie, Parigi, Sara, Jacob, Jean-Marie, Cheng, Hung-Wei, Evren, Elza, Das, Srustidhar, Czarnewski, Paulo, Sleiers, Natalie, Melo-Gonzalez, Felipe, Kvedaraite, Egle, Svensson, Mattias, Scandella, Elke, Hepworth, Matthew, Huber, Samuel, Ludewig, Burkhard, Peduto, Lucie, Villablanca, Eduardo, Veiga-Fernandes, Henrique, Pereira, Joao, Flavell, Richard, Willinger, Tim

Publikováno v: Immunity
Immunity, Elsevier, 2018, 48 (1), pp.120-132.e8. ⟨10.1016/j.immuni.2017.11.020⟩
Immunity, 2018, 48 (1), pp.120-132.e8. ⟨10.1016/j.immuni.2017.11.020⟩
Emgard, J, Kammoun, H, Garcia-Cassani, B, Chesne, J, Parigi, S M, Jacob, J-M, Cheng, H-W, Evren, E, Das, S, Czarnewski, P, Sleiers, N, Melo Gonzalez, F, Kvedaraite, E, Svensson, M, Scandella, E, Hepworth, M, Huber, S, Ludewig, B, Peduto, L, Villablanca, E J, Veiga-Fernandes, H, Pereira, J P, Flavell, R A & Willinger, T 2018, ' Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation ', Immunity, vol. 48, no. 1, pp. 120-132 . https://doi.org/10.1016/j.immuni.2017.11.020

Summary Group 3 innate lymphoid cells (ILC3s) sense environmental signals and are critical for tissue integrity in the intestine. Yet, which signals are sensed and what receptors control ILC3 function remain poorly understood. Here, we show that ILC3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b71a980e84fd062413a2217b7e4e9e3
https://hal-pasteur.archives-ouvertes.fr/pasteur-01716331/document

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