Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Slavina, Surcheva"'
Autor:
Pavlina Andreeva-Gateva, Milen Hristov, Margarita Strokova-Stoilova, Natasha Ivanova, Zafer Sabit, Slavina Surcheva, Mihail Beliakov, Georgi Karakashev, Ivan Sukhov, Daria Belinskaya, Natalia Shestakova
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27367- (2024)
Both peripheral neuropathy and depression can be viewed as neurodegeneration's consequences of diabetes, at least in part coexisting with or resulting from sodium-calcium dysbalance. This study aims to assess the therapeutic potential of the orally a
Externí odkaz:
https://doaj.org/article/2fb2f3e739ce45369dd5a2122b00ec5e
Autor:
Velko Minchev, Nadya Hristova-Avakumova, Kalina Kamenova, Liliya Atanasova, Marin Angelov, Lozan Todorov, Slavina Surcheva, Rumen Nikolov
Publikováno v:
Folia Medica, Vol 63, Iss 5, Pp 760-767 (2021)
Introduction: Colorectal cancer is the third most common cancer type worldwide. Fluoropyrimidines and their prodrug-based regimens are widely applied as primary medications. The main enzyme responsible for the rate-limiting step in pyrimidine and for
Externí odkaz:
https://doaj.org/article/a876796cbb9b49189af579081ee8639a
Autor:
Jana Tchekalarova, Natasha Ivanova, Zlatina Nenchovska, Rumiana Tzoneva, Tzveta Stoyanova, Veselina Uzunova, Slavina Surcheva, Alex Tzonev, Violina T. Angelova, Pavlina Andreeva-Gateva
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1566-1579 (2020)
Based on the pharmacophore model of melatonin (MT1) receptor, we recently synthesized a series of indole derivatives that showed anticonvulsant activity with low neurotoxicity and hepatotoxicity in rodents. In the present study, the three most potent
Externí odkaz:
https://doaj.org/article/bf5eca59897f48d085a387a99592b627
Autor:
Stanislav Marchev, Pavlina Andreeva-Gateva, Roumiana Tzoneva, Slavina Surcheva, Alex Tzonev, Kalina Kamenova, Violina T. Angelova, Jana Tchekalarova, Mila Vlaskovska
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 98-107 (2019)
We have recently identified several aroylhydrazone-based molecular hybrids with antiseizure activity. We aimed to investigate the analgesic activity of these molecules further. Male ICR mice were injected intraperitoneally with the tested substances
Externí odkaz:
https://doaj.org/article/c2cd2ac56de845f3b7e5d8a8a2a7ba0c
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 31, Iss 6, Pp 1226-1230 (2017)
Epilepsy is one of most reported neurological disorders after migraine, stroke and Alzheimer's disease. Empiric clinical data reveal that seizures and epilepsy more likely affect men than women. The aim of present study was to investigate the effect
Externí odkaz:
https://doaj.org/article/2a5824dfc9464f1dbeea143c10f3bcec
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 31, Iss 3, Pp 568-573 (2017)
Pregabalin and gabapentin are amino-acid derivatives of gamma-aminobutyric acid. They have a high affinity to the α2δ protein in the central nervous system and both have been shown to be effective for neuropathic pain disorder. The aim of this stud
Externí odkaz:
https://doaj.org/article/52549651c8304a92af20a8a38c845412
Autor:
Marin P. Angelov, Velko Minchev, Kalina Kamenova, Liliya A. Atanasova, Slavina Surcheva, Nadya Hristova-Avakumova, Rumen Nikolov, Lozan Todorov
Publikováno v:
Folia Medica, Vol 63, Iss 5, Pp 760-767 (2021)
Introduction: Colorectal cancer is the third most common cancer type worldwide. Fluoropyrimidines and their prodrug-based regimens are widely applied as primary medications. The main enzyme responsible for the rate-limiting step in pyrimidine and for
Autor:
Roumiana Tzoneva, Slavina Surcheva, Stanislav Marchev, Violina T. Angelova, Alex Tzonev, Kalina Kamenova, Mila Vlaskovska, Pavlina Andreeva-Gateva, Jana Tchekalarova
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 98-107 (2019)
We have recently identified several aroylhydrazone-based molecular hybrids with antiseizure activity. We aimed to investigate the analgesic activity of these molecules further. Male ICR mice were injected intraperitoneally with the tested substances