Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Slavena Vylkova"'
Autor:
Bettina Böttcher, Sandra D. Kienast, Johannes Leufken, Cristian Eggers, Puneet Sharma, Christine M. Leufken, Bianka Morgner, Hannes C. A. Drexler, Daniela Schulz, Stefanie Allert, Ilse D. Jacobsen, Slavena Vylkova, Sebastian A. Leidel, Sascha Brunke
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTtRNA modifications play important roles in maintaining translation accuracy in all domains of life. Disruptions in the tRNA modification machinery, especially of the anticodon stem loop, can be lethal for many bacteria and lead to a broad ran
Externí odkaz:
https://doaj.org/article/a114f64854bb4cc889551a3b09495768
Autor:
Antje Häder, Sascha Schäuble, Jan Gehlen, Nadja Thielemann, Benedikt C. Buerfent, Vitalia Schüller, Timo Hess, Thomas Wolf, Julia Schröder, Michael Weber, Kerstin Hünniger, Jürgen Löffler, Slavena Vylkova, Gianni Panagiotou, Johannes Schumacher, Oliver Kurzai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Innate immune responses vary by pathogen and host genetics. We analyze quantitative trait loci (eQTLs) and transcriptomes of monocytes from 215 individuals stimulated by fungal, Gram-negative or Gram-positive bacterial pathogens. We identify
Externí odkaz:
https://doaj.org/article/2cf885178e8843868db0af93d72f7768
Autor:
Bettina Böttcher, Dominik Driesch, Thomas Krüger, Enrico Garbe, Franziska Gerwien, Olaf Kniemeyer, Axel A. Brakhage, Slavena Vylkova
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Candida albicans biofilm maturation is accompanied by enhanced expression of amino acid acquisition genes. Three state-of-the-art omics techniques were applied to detail the importance of active amino acid uptake during biofilm development.
Externí odkaz:
https://doaj.org/article/0758b4b5e97644d392ae207bf16dedde
Autor:
Philipp Brandt, Mohammad H. Mirhakkak, Lysett Wagner, Dominik Driesch, Anna Möslinger, Pauline Fänder, Sascha Schäuble, Gianni Panagiotou, Slavena Vylkova
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Candida auris, a multidrug-resistant human fungal pathogen that causes outbreaks of invasive infections, emerged as four distinct geographical clades. Previous studies identified genomic and proteomic differences in nutrient utilization on c
Externí odkaz:
https://doaj.org/article/c766e9d3d18f44128506a87339087fc2
Autor:
Christian H. Luther, Philipp Brandt, Slavena Vylkova, Thomas Dandekar, Tobias Müller, Marcus Dittrich
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Fungal infections are a major global health burden where Candida albicans is among the most common fungal pathogen in humans and is a common cause of invasive candidiasis. Fungal phenotypes, such as those related to morphology, proliferation and viru
Externí odkaz:
https://doaj.org/article/d96b6ee23af1454d80f2bc21c7265f97
Autor:
Raquel Alonso-Roman, Antonia Last, Mohammad H. Mirhakkak, Jakob L. Sprague, Lars Möller, Peter Großmann, Katja Graf, Rena Gratz, Selene Mogavero, Slavena Vylkova, Gianni Panagiotou, Sascha Schäuble, Bernhard Hube, Mark S. Gresnigt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Commensal bacteria such as Lactobacillus rhamnosus can inhibit the pathogenicity of the fungus Candida albicans. Here, Alonso-Roman et al. investigate the interplay between C. albicans, L. rhamnosus and intestinal epithelial cells, showing that chang
Externí odkaz:
https://doaj.org/article/4b43000037904e2aabfc1a7cd0eee186
Autor:
Yasmine Rebai, Lysett Wagner, Mayssa Gnaien, Merle L. Hammer, Mario Kapitan, Maria Joanna Niemiec, Wael Mami, Amor Mosbah, Erij Messadi, Helmi Mardassi, Slavena Vylkova, Ilse D. Jacobsen, Sadri Znaidi
Publikováno v:
Microorganisms, Vol 11, Iss 8, p 1929 (2023)
Candida albicans is a pathobiont of the gastrointestinal tract. It can contribute to the diversity of the gut microbiome without causing harmful effects. When the immune system is compromised, C. albicans can damage intestinal cells and cause invasiv
Externí odkaz:
https://doaj.org/article/95ef2d6f969a469b8f4c01e0f2cd356c
Autor:
Enrico Garbe, Franziska Gerwien, Dominik Driesch, Tina Müller, Bettina Böttcher, Markus Gräler, Slavena Vylkova
Publikováno v:
mSystems, Vol 7, Iss 6 (2022)
ABSTRACT The yeast-to-hypha transition is a key virulence attribute of the opportunistic human fungal pathogen Candida albicans, since it is closely tied to infection-associated processes such as tissue invasion and escape from phagocytes. While the
Externí odkaz:
https://doaj.org/article/595b17b940ee44ee8379cb4845fd5bca
Autor:
Philipp Brandt, Franziska Gerwien, Lysett Wagner, Thomas Krüger, Bernardo Ramírez-Zavala, Mohammad H. Mirhakkak, Sascha Schäuble, Olaf Kniemeyer, Gianni Panagiotou, Axel A. Brakhage, Joachim Morschhäuser, Slavena Vylkova
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Protein kinases play a crucial role in regulating cellular processes such as growth, proliferation, environmental adaptation and stress responses. Serine-arginine (SR) protein kinases are highly conserved in eukaryotes and regulate fundamental proces
Externí odkaz:
https://doaj.org/article/95717107431b49bb97cc7be1d69c667f
Autor:
Christin von Müller, Fionnuala Bulman, Lysett Wagner, Daniel Rosenberger, Alessandra Marolda, Oliver Kurzai, Petra Eißmann, Ilse D. Jacobsen, Birgit Perner, Peter Hemmerich, Slavena Vylkova
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Burn wounds are highly susceptible sites for colonization and infection by bacteria and fungi. Large wound surface, impaired local immunity, and broad-spectrum antibiotic therapy support growth of opportunistic fungi such as Candida albicans
Externí odkaz:
https://doaj.org/article/ba837634657b4b858d2cc5178fea1d41