Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats.

Autor: Edwards MM; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Nguyen HK; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Dodson AD; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Herbertson AJ; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Honeycutt MK; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Slattery JD; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Rambousek JR; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Tsui E; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Wolden-Hanson T; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Wietecha TA; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.; UW Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, WA 98109., Graham JL; Department of Nutrition, University of California, Davis, CA 95616, USA., Tapia GP; UTEP Systems Neuroscience Laboratory, Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Sikkema CL; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington., O'Brien KD; Division of Cardiology, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.; UW Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, WA 98109., Mundinger TO; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA., Peskind ER; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington., Ryu V; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Havel PJ; Department of Nutrition, University of California, Davis, CA 95616, USA.; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Khan AM; UTEP Systems Neuroscience Laboratory, Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA., Taborsky GJ Jr; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA.; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA., Blevins JE; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA.; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.

Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats.

Autor: Slattery JD; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Rambousek JR; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Tsui E; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Honeycutt MK; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Goldberg M; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., Graham JL; Department of Nutrition, University of California, Davis, CA 95616, USA., Wietecha TA; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.; UW Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, WA 98109., Wolden-Hanson T; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA., O'Brien KD; Division of Cardiology, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.; UW Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, WA 98109., Havel PJ; Department of Nutrition, University of California, Davis, CA 95616, USA.; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA., Blevins JE; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA 98108, USA.; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 30. Date of Electronic Publication: 2024 Sep 30.

The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-dependent manner.

Autor: Blevins JE; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States.; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA, United States., Honeycutt MK; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Slattery JD; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Goldberg M; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Rambousek JR; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Tsui E; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Dodson AD; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Shelton KA; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States., Salemeh TS; Seattle Children's Research Institute, Seattle, WA, United States., Elfers CT; Seattle Children's Research Institute, Seattle, WA, United States., Chichura KS; Department of Chemistry, Syracuse University, Syracuse, NY, United States., Ashlaw EF; Department of Chemistry, Syracuse University, Syracuse, NY, United States., Zraika S; VA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States.; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA, United States., Doyle RP; Department of Chemistry, Syracuse University, Syracuse, NY, United States.; Departments of Medicine and Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY, United States., Roth CL; Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, United States.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Jul 22; Vol. 15, pp. 1432928. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).

The Novel Chimeric Multi-Agonist Peptide (GEP44) Reduces Energy Intake and Body Weight in Male and Female Diet-Induced Obese Mice in a Glucagon-Like Peptide-1 Receptor-Dependent Manner.

Autor: Blevins JE, Honeycutt MK, Slattery JD, Goldberg M, Rambousek JR, Tsui E, Dodson AD, Shelton KA, Salemeh TS, Elfers CT, Chichura KS, Ashlaw EF, Zraika S, Doyle RP, Roth CL

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 21. Date of Electronic Publication: 2024 May 21.