Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sladjana Dukić-Stefanović"'
Autor:
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Daniel Gündel, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Friedrich-Alexander Ludwig, Klaus Kopka, Peter Brust, Finn K. Hansen, Matthias Scheunemann
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 324 (2022)
The degree of acetylation of lysine residues on histones influences the accessibility of DNA and, furthermore, the gene expression. Histone deacetylases (HDACs) are overexpressed in various tumour diseases, resulting in the interest in HDAC inhibitor
Externí odkaz:
https://doaj.org/article/830003203e3b458b81afb939ef4979aa
Autor:
Thu Hang Lai, Susann Schröder, Magali Toussaint, Sladjana Dukić-Stefanović, Mathias Kranz, Friedrich-Alexander Ludwig, Steffen Fischer, Jörg Steinbach, Winnie Deuther-Conrad, Peter Brust, Rareş-Petru Moldovan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2285 (2021)
The adenosine A2A receptor (A2AR) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during t
Externí odkaz:
https://doaj.org/article/76b84321f4d2489c95d5100f3eac0c6c
Autor:
Thu Hang Lai, Magali Toussaint, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Mathias Kranz, Winnie Deuther-Conrad, Rareş-Petru Moldovan, Peter Brust
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1182 (2021)
The adenosine A2A receptor (A2AR) has emerged as a potential non-dopaminergic target for the treatment of Parkinson’s disease and, thus, the non-invasive imaging with positron emission tomography (PET) is of utmost importance to monitor the recepto
Externí odkaz:
https://doaj.org/article/f7c5350037394682a514f66ed72e630f
Autor:
Ivana I. Jevtić, Thu Hang Lai, Jelena Z. Penjišević, Sladjana Dukić-Stefanović, Deana B. Andrić, Peter Brust, Sladjana V. Kostić-Rajačić, Rodrigo Teodoro
Publikováno v:
Molecules, Vol 25, Iss 21, p 4941 (2020)
Herein, we report on the synthesis and pharmacological evaluation of ten novel fluorinated cinnamylpiperazines as potential monoamine oxidase B (MAO-B) ligands. The designed derivatives consist of either cinnamyl or 2-fluorocinnamyl moieties connecte
Externí odkaz:
https://doaj.org/article/d29f34f7b5de46af9ce9104eb53eab9a
Autor:
Susann Schröder, Thu Hang Lai, Magali Toussaint, Mathias Kranz, Alexandra Chovsepian, Qi Shang, Sladjana Dukić-Stefanović, Winnie Deuther-Conrad, Rodrigo Teodoro, Barbara Wenzel, Rareş-Petru Moldovan, Francisco Pan-Montojo, Peter Brust
Publikováno v:
Molecules, Vol 25, Iss 7, p 1633 (2020)
The adenosine A2A receptor (A2AR) is regarded as a particularly appropriate target for non-dopaminergic treatment of Parkinson’s disease (PD). An increased A2AR availability has been found in the human striatum at early stages of PD and in patients
Externí odkaz:
https://doaj.org/article/a6ba38be238e498699ccd57b2c5d72c9
Autor:
Thu Hang, Lai, Susann, Schröder, Magali, Toussaint, Sladjana, Dukić-Stefanović, Mathias, Kranz, Friedrich-Alexander, Ludwig, Steffen, Fischer, Jörg, Steinbach, Winnie, Deuther-Conrad, Peter, Brust, Rareş-Petru, Moldovan
Publikováno v:
International Journal of Molecular Sciences
The adenosine A2A receptor (A2AR) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during t
Autor:
Thu Hang, Lai, Magali, Toussaint, Rodrigo, Teodoro, Sladjana, Dukić-Stefanović, Mathias, Kranz, Winnie, Deuther-Conrad, Rareş-Petru, Moldovan, Peter, Brust
Publikováno v:
International Journal of Molecular Sciences
The adenosine A2A receptor (A2AR) has emerged as a potential non-dopaminergic target for the treatment of Parkinson’s disease and, thus, the non-invasive imaging with positron emission tomography (PET) is of utmost importance to monitor the recepto
Autor:
Thu Hang, Lai, Magali, Toussaint, Rodrigo, Teodoro, Sladjana, Dukić-Stefanović, Daniel, Gündel, Friedrich-Alexander, Ludwig, Barbara, Wenzel, Susann, Schröder, Bernhard, Sattler, Rareş-Petru, Moldovan, Björn H, Falkenburger, Osama, Sabri, Winnie, Deuther-Conrad, Peter, Brust
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose The adenosine A2A receptor has emerged as a therapeutic target for multiple diseases, and thus the non-invasive imaging of the expression or occupancy of the A2A receptor has potential to contribute to diagnosis and drug development. We aimed
Autor:
Jelena Z. Penjišević, Vladimir B. Šukalović, Sladjana Dukic-Stefanovic, Winnie Deuther-Conrad, Deana B. Andrić, Slađana V. Kostić-Rajačić
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 4, Pp 104636- (2023)
Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A recep
Externí odkaz:
https://doaj.org/article/e81153791b7d434e899fb4884aefdfa0
Autor:
Valérie Weber, Lucie Arnaud, Sladjana Dukic-Stefanovic, Barbara Wenzel, Valérie Roux, Jean-Michel Chezal, Thu-Hang Lai, Rodrigo Teodoro, Klaus Kopka, Elisabeth Miot-Noirault, Winnie Deuther-Conrad, Aurélie Maisonial-Besset
Publikováno v:
Molecules, Vol 27, Iss 12, p 3766 (2022)
Isocitrate dehydrogenases (IDHs) are metabolic enzymes commonly mutated in human cancers (glioma, acute myeloid leukaemia, chondrosarcoma, and intrahepatic cholangiocarcinoma). These mutated variants of IDH (mIDH) acquire a neomorphic activity, namel
Externí odkaz:
https://doaj.org/article/d2c3674b007a4d6ea932059eb464d1ec