An 8-aminoquinoline-naphthyl copper complex causes apoptotic cell death by modulating the expression of apoptotic regulatory proteins in breast cancer cells.

Autor: Myeza N; Division of Pharmacology, Department of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, South Africa., Slabber C; Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, 1 Jan Smut Ave, Braamfontein, Johannesburg, 2017, South Africa., Munro OQ; Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, 1 Jan Smut Ave, Braamfontein, Johannesburg, 2017, South Africa; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK., Sookai S; Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, 1 Jan Smut Ave, Braamfontein, Johannesburg, 2017, South Africa., Zacharias SC; School of Chemistry and Physics, University of KwaZulu-Natal, King Edward Drive, Pietermaritzburg, Scottsville, 3209, South Africa., Martins-Furness C; Division of Pharmacology, Department of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, South Africa., Harmse L; Division of Pharmacology, Department of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, South Africa. Electronic address: Leonie.Harmse@wits.ac.za.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2024 Sep 05; Vol. 978, pp. 176764. Date of Electronic Publication: 2024 Jun 20.

A cytotoxic bis(1,2,3-triazol-5-ylidene)carbazolide gold(III) complex targets DNA by partial intercalation

Autor: van der Westhuizen, D. (Danielle), Slabber, C. A. (Cathryn A.), Fernandes, M. A. (Manuel A.), Joubert, D. F. (Daniël F.), Kleinhans, G. (George), van der Westhuizen, J. (Johan), Stander, A. (André), Munro, O. Q. (Orde Q.), Bezuidenhout, D. I. (Daniela I.)

The syntheses of bis(triazolium)carbazole precursors and their corresponding coinage metal (Au, Ag) complexes are reported. For alkylated triazolium salts, di- or tetranuclear complexes with bridging ligands were isolated, while the bis(aryl) analogu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::409da61885be2690326e27ee716d1921
http://urn.fi/urn:nbn:fi-fe2021062940471

First line therapy with paclitaxel (Taxol ®) and pegylated liposomal doxorubicin (Caelyx ®) in patients with metastatic breast cancer: a multicentre phase II study

Autor: Vorobiof, D.A ^*, Rapoport, B.L, Chasen, M.R, Slabber, C, McMichael, G, Eek, R, Mohammed, C

Publikováno v: In The Breast 2004 13(3):219-226

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PCAT19: the role in cancer pathogenesis and beyond.

Autor: Hu, Haijun, Luo, Hongliang, Deng, Ziqing

Publikováno v: Frontiers in Cell & Developmental Biology; 2024, p1-13, 13p