Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

Autor: Bancroft, EK, Page, EC, Castro, E, Lilja, H, Vickers, A, Sjoberg, D, Assel, M, Foster, CS, Mitchell, G, Drew, K, Maehle, L, Axcrona, K, Evans, DG, Bulman, B, Eccles, D, McBride, D, van Asperen, C, Vasen, H, Kiemeney, LA, Ringelberg, J, Cybulski, C, Wokolorczyk, D, Selkirk, C, Hulick, PJ, Bojesen, A, Skytte, AB, Lam, J, Taylor, L, Oldenburg, R, Cremers, R, Verhaegh, G, van Zelst-Stams, WA, Oosterwijk, JC, Blanco, I, Salinas, M, Cook, J, Rosario, DJ, Buys, S, Conner, T, Ausems, MG, Ong, KR, Hoffman, J, Domchek, S, Powers, J, Teixeira, MR, Maia, S, Foulkes, WD, Taherian, N, Ruijs, M, Helderman-van den Enden, AT, Izatt, L, Davidson, R, Adank, MA, Walker, L, Schmutzler, R, Tucker, K, Kirk, J, Hodgson, S, Harris, M, Douglas, F, Lindeman, GJ, Zgajnar, J, Tischkowitz, M, Clowes, VE, Susman, R, Cajal, TRY, Patcher, N, Gadea, N, Spigelman, A, van Os, T, Liljegren, A, Side, L, Brewer, C, Brady, AF, Donaldson, A, Stefansdottir, V, Friedman, E, Chen-Shtoyerman, R, Amor, DJ, Copakova, L, Barwell, J, Giri, VN, Murthy, V, Nicolai, N, Teo, SH, Greenhalgh, L, Strom, S, Henderson, A, McGrath, J, Gallagher, D, Aaronson, N, Ardern-Jones, A, Bangma, C, Dearnaley, D, Costello, P, Eyfjord, J, Rothwell, J, Falconer, A, Gronberg, H, Hamdy, FC, Johannsson, O, Khoo, V, Kote-Jarai, Z, Lubinski, J, Axcrona, U, Melia, J, McKinley, J, Mitra, AV, Moynihan, C, Rennert, G, Suri, M, Wilson, P, Killick, E, Moss, S, Eeles, RA, Taylor, N, Pope, J, Saya, S, Martin, S, Keating, D, Petelin, L, Murphy, M, Doherty, R, Pratt, S, Murphy, D, Cleeve, L, Miller, C, Stapleton, A, Chong, M, Suthers, G, Andrews, L, Duffy, J, Millard, R, Ward, R, Williams, R, Stricker, P, Bowman, M, Patel, M, O'Connell, S, Hunt, C, Smyth, C, Frydenberg, M, Shackleton, K, McGaughran, J, Boon, M, Pachter, N, Townshend, S, Schofield, L, Gleeson, M, Scott, R, Burke, J, Patterson, B, Bacic, S, Swindle, P, Aprikian, A, Bojeson, A, Cruger, D, Osther, P, Gerdes, AM, Rhiem, K, Luedtke-Heckenkamp, K, Ochsendorf, N, Fiddike, K, Sarin, R, Awatagiri, K, Ghonge, S, Kowtal, P, Mulgund, G, Bambury, R, Farrell, M, Gallagher, F, Ben-Yehoshua, SJ, Nissani, R, Appelman, Z, Moriel, E, Radice, P, Valdagni, R, Magnani, T, Meng, TH, Yoon, SY, Thong, MK, Kiemeney, B, Van der Luijt, RB, Moller, P, Brennhovd, B, Medvik, H, Hanslien, E, Peixoto, A, Henrique, R, Oliveira, J, Goncalves, N, Araujo, L, Seixas, M, Joao, PS, Nogueira, P, Krajc, M, Vrecar, A, Capella, G, Fisas, D, Balmana, J, Morote, J, Hjalm-Eriksson, M, Ekdahl, KJ, Carlsson, S, Hanson, H, Shanley, S, Goh, C, Wiggins, J, Kohut, K, Van As, N, Thompson, A, Ogden, C, Borley, N, Woodhouse, C, Kumar, P, Mercer, C, Paterson, J, Taylor, A, Newcombe, B, Halliday, D, Stayner, B, Fleming-Brown, D, Brice, G, Homfray, T, Hammond, C, Potter, A, Renton, C, Searle, A, Hill, K, Goodman, S, Garcia, L, Devlin, G, Everest, S, Nadolski, M, Jobson, I, Paez, E, Tomkins, S, Pichert, G, Jacobs, C, Langman, C, Weston, M, Dorkins, H, Melville, A, Kosicka-Slawinska, M, Cummings, C, Kiesel, V, Bartlett, M, Randhawa, K, Ellery, N, Male, A, Simon, K, Rees, K, Compton, C, Tidey, L, Nevitt, L, Ingram, S, Catto, J, Howson, J, Chapman, C, Cole, T, Heaton, T, Burgess, L, Longmuir, M, Watt, C, Duncan, A, Kockelbergh, R, Sattar, A, Kaemba, B, Sidat, Z, Patel, N, Siguake, K, Birt, A, Poultney, U, Umez-Eronini, N, Mom, J, Roberts, G, Woodward, A, Sutton, V, Cornford, P, Treherne, K, Griffiths, J, Cogley, L, Rubinstein, W, Brendler, C, Helfand, B, McGuire, M, Kaul, K, Shevrin, D, Weissman, S, Newlin, A, Vogel, K, Weiss, S, Goldgar, D, Venne, V, Stephenson, R, Dechet, C, Arun, B, Davis, JW, Yamamura, Y, Gross, L

Publikováno v: EUROPEAN UROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background: Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::c5a815b40531304e841ccbdc7624fba7
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9155

Tofacitinib Does Not Impair Sperm Quality in Men With Ulcerative Colitis.

Autor: Grosen A; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., Bellaguarda E; Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Liljeqvist-Soltic I; Reproductive Medicine Centre, Skaane University Hospital, Malmoe, Sweden., Skytte AB; Cryos International, Aarhus, Denmark., Hanauer SB; Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Kelsen J; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2024 Aug 23. Date of Electronic Publication: 2024 Aug 23.

DNA mismatch and damage patterns revealed by single-molecule sequencing.

Autor: Liu MH; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Costa BM; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Bianchini EC; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Choi U; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Bandler RC; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA., Lassen E; Cryos International Sperm and Egg Bank, Aarhus, Denmark., Grońska-Pęski M; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Schwing A; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Murphy ZR; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Rosenkjær D; Cryos International Sperm and Egg Bank, Aarhus, Denmark., Picciotto S; Department of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Bianchi V; Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Stengs L; Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Edwards M; Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Nunes NM; Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Loh CA; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Truong TK; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Brand RE; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Pastinen T; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA., Wagner JR; Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Skytte AB; Cryos International Sperm and Egg Bank, Aarhus, Denmark., Tabori U; Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Shoag JE; Department of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Evrony GD; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA. gilad.evrony@nyulangone.org.; Department of Pediatrics, Department of Neuroscience & Physiology, Institute for Systems Genetics, Perlmutter Cancer Center, and Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA. gilad.evrony@nyulangone.org.

Publikováno v: Nature [Nature] 2024 Jun; Vol. 630 (8017), pp. 752-761. Date of Electronic Publication: 2024 Jun 12.

The impact of acute SARS-CoV-2 on testicular function including insulin-like factor 3 (INSL3) in men with mild COVID-19: A longitudinal study.

Autor: Lauritsen MP; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Kristensen TL; Department of Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Hansen CB; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Schneider UV; Department of Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Talbot AL; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Skytte AB; Cryos International, Aarhus, Denmark., Petersen JH; Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark., Johannsen TH; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Zedeler A; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Albrethsen J; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Juul A; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Priskorn L; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Jørgensen N; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Westh H; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark., Freiesleben NC; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Nielsen HS; Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: Andrology [Andrology] 2024 Feb; Vol. 12 (2), pp. 437-446. Date of Electronic Publication: 2023 Jul 22.

Single duplex DNA sequencing with CODEC detects mutations with high sensitivity.

Autor: Bae JH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Liu R; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Roberts E; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen E; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tabrizi S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Rhoades J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Blewett T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Xiong K; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gydush G; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shea D; Broad Institute of MIT and Harvard, Cambridge, MA, USA., An Z; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Patel S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Cheng J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sridhar S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Liu MH; Center for Human Genetics and Genomics, Departments of Pediatrics and Neuroscience & Physiology, New York University Grossman School of Medicine, New York City, NY, USA., Lassen E; Cryos International, Aarhus, Denmark., Skytte AB; Cryos International, Aarhus, Denmark., Grońska-Pęski M; Center for Human Genetics and Genomics, Departments of Pediatrics and Neuroscience & Physiology, New York University Grossman School of Medicine, New York City, NY, USA., Shoag JE; University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH, USA., Evrony GD; Center for Human Genetics and Genomics, Departments of Pediatrics and Neuroscience & Physiology, New York University Grossman School of Medicine, New York City, NY, USA., Parsons HA; Dana-Farber Cancer Institute, Boston, MA, USA., Mayer EL; Dana-Farber Cancer Institute, Boston, MA, USA., Makrigiorgos GM; Dana-Farber Cancer Institute, Boston, MA, USA., Golub TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Adalsteinsson VA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. viktor@broadinstitute.org.

Publikováno v: Nature genetics [Nat Genet] 2023 May; Vol. 55 (5), pp. 871-879. Date of Electronic Publication: 2023 Apr 27.