Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Skyler Uhl"'
Autor:
Lissenya B. Argueta, Lauretta A. Lacko, Yaron Bram, Takuya Tada, Lucia Carrau, André Figueiredo Rendeiro, Tuo Zhang, Skyler Uhl, Brienne C. Lubor, Vasuretha Chandar, Cristianel Gil, Wei Zhang, Brittany J. Dodson, Jeroen Bastiaans, Malavika Prabhu, Sean Houghton, David Redmond, Christine M. Salvatore, Yawei J. Yang, Olivier Elemento, Rebecca N. Baergen, Benjamin R. tenOever, Nathaniel R. Landau, Shuibing Chen, Robert E. Schwartz, Heidi Stuhlmann
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104223- (2022)
Summary: The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and subgenomic RNA in 22 out of 52 placentas. Placentas from two moth
Externí odkaz:
https://doaj.org/article/10e8c8bb49714f07ba4f189eb87775e5
Autor:
James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%. HCPS cases are rare, with appro
Externí odkaz:
https://doaj.org/article/a07b27d030d04b76a86ce12028632023
Autor:
Skyler Uhl, Chanyong Jang, Justin J. Frere, Tristan X. Jordan, Anne E. Simon, Benjamin R. tenOever
Publikováno v:
Journal of Virology. 97
All life at the cellular level has the capacity to induce an antiviral response. Here, we examine the result of imposing the antiviral response of one branch of life onto another and find evidence for conflict.
Autor:
Yaoxing Huang, Jiajun Zhu, Todd Evans, Yuling Han, Liuliu Yang, Vasuretha Chandar, Yaron Bram, Joshua A. Acklin, David D. Ho, Alain C. Borczuk, Benjamin E. Nilsson-Payant, Benjamin R. tenOever, Sean Houghton, Fabrice Jaffré, Jenny Xiang, Tuo Zhang, Shuibing Chen, David Redmond, Zhengming Chen, Skyler Uhl, Chanel Richardson, Jean K. Lim, Pengfei Wang, Robert E. Schwartz
Publikováno v:
Circ Res
Rationale: While respiratory failure is a frequent and clinically significant outcome of coronavirus disease 2019 (COVID-19), cardiac complications are a common feature in hospitalized COVID-19 patients and are associated with worse patient outcomes.
Autor:
Crystal Yuri Oh, Ilona Golynker, Sarah E. Gilpin, Haiqing Bai, Rachelle Prantil-Baun, Amanda Jiang, Danni Y. Zhu, Steven P. Gygi, Mercy Soong, Melissa Rodas, Marisa McGrath, Longlong Si, Robert Haupt, Seongmin Kim, James Logue, Daniel Blanco-Melo, Tristan X. Jordan, Randy A. Albrecht, Rasmus Møller, Tian Zhang, Donald E. Ingber, Kohei Oishi, Justin J. Frere, Kambez H. Benam, Daisy A. Hoagland, Girija Goyal, Kenneth E. Carlson, Wen-Chun Liu, Rani K. Powers, Shu Horiuchi, Benjamin E. Nilsson-Payant, Skyler Uhl, Roberto Plebani, Matthew B. Frieman, Benjamin R. tenOever, Stuart Weston, Atiq Nurani, Wuji Cao
Publikováno v:
Nature biomedical engineering
The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines that do not recapitulate human physiology at the tissue and organ lev
Autor:
Lissenya B. Argueta, Lauretta A. Lacko, Yaron Bram, Takuya Tada, Lucia Carrau, André Figueiredo Rendeiro, Tuo Zhang, Skyler Uhl, Brienne C. Lubor, Vasuretha Chandar, Cristianel Gil, Wei Zhang, Brittany J. Dodson, Jeroen Bastiaans, Malavika Prabhu, Sean Houghton, David Redmond, Christine M. Salvatore, Yawei J. Yang, Olivier Elemento, Rebecca N. Baergen, Benjamin R. tenOever, Nathaniel R. Landau, Shuibing Chen, Robert E. Schwartz, Heidi Stuhlmann
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
SARS-CoV-2 infection during pregnancy leads to an increased risk of adverse pregnancy outcomes. Although the placenta itself can be a target of virus infection, most neonates are virus free and are born healthy or recover quickly. Here, we investigat
Autor:
Joshua A. Acklin, Maryline Panis, Christina A Higgins, Skyler Uhl, Yaron Bram, Daniel Blanco-Melo, Benjamin R. tenOever, Benjamin E. Nilsson-Payant, Robert E. Schwartz, Ashley S. Doane, Vasuretha Chandar, Rohit Chandwani, Phillip Cohen, Brad R. Rosenberg, Adrien Grimont, Roosheel S. Patel, Olivier Elemento, Jean K. Lim
Publikováno v:
Journal of Virology
SARS-CoV-2, the etiological agent of COVID-19, is characterized by a delay in type I interferon (IFN-I)-mediated antiviral defenses alongside robust cytokine production. Here, we investigate the underlying molecular basis for this imbalance and impli
Autor:
Marianna Zazhytska, Albana Kodra, Daisy A. Hoagland, Justin Frere, John F. Fullard, Hani Shayya, Natalie G. McArthur, Rasmus Moeller, Skyler Uhl, Arina D. Omer, Max E. Gottesman, Stuart Firestein, Qizhi Gong, Peter D. Canoll, James E. Goldman, Panos Roussos, Benjamin R. tenOever, null Jonathan B. Overdevest, Stavros Lomvardas
Publikováno v:
Cell
Cell, vol 185, iss 6
Cell, vol 185, iss 6
SARS-CoV-2 infects less than 1% of cells in the human body, yet it can cause severe damage in a variety of organs. Thus, deciphering the non-cell autonomous effects of SARS-CoV-2 infection is imperative for understanding the cellular and molecular di
Autor:
Rebecca N. Baergen, Brienne Lubor, Yawei J. Yang, Yaron Bram, Malavika Prabhu, Brittany Dodson, Takuya Tada, Benjamin R. tenOever, Christianel Gil, Tuo Zhang, Wei Zhang, Shuibing Chen, Jeroen Bastiaans, Vasuretha Chandar, Nathaniel R. Landau, Lissenya B. Argueta, Skyler Uhl, Heidi Stuhlmann, Christine M. Salvatore, Lauretta A. Lacko, Robert E. Schwartz, Lucia Carrau
SARS-CoV-2 infection during pregnancy leads to an increased risk of adverse pregnancy outcomes. Although the placenta itself can be a target of virus infection, most neonates are virus free and are born healthy or recover quickly. Here, we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1432257367256eb5265b9ef29829c4a
https://doi.org/10.1101/2021.06.01.446676
https://doi.org/10.1101/2021.06.01.446676
Autor:
Benjamin E. Nilsson-Payant, Benhur Lee, Silke Olschewski, Benjamin R. tenOever, Maryline Panis, Maria Rosenthal, César Muñoz-Fontela, Skyler Uhl, Daniel Blanco-Melo, Beatriz Escudero-Pérez, Patricia A. Thibault
Publikováno v:
Journal of Virology
Negative-sense RNA viruses comprise some of the most important known human pathogens, including influenza A virus, measles virus, and Ebola virus. These viruses possess RNA genomes that are unreadable to the host, as they require specific viral RNA-d