Výsledky vyhledávání - "Skylar Korek"

Akademický článek

Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments

Autor: Susan Raju Paul, Anja Scholzen, Patrick M. Reeves, Robert Shepard, Joshua M. Hess, Richard K. Dzeng, Skylar Korek, Anja Garritsen, Mark C. Poznansky, Ann E. Sluder

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionQ fever, caused by the intracellular bacterium Coxiella burnetii, is considered an occupational and biodefense hazard and can result in debilitating long-term complications. While natural infection and vaccination induce humoral and cellu

Externí odkaz: https://doaj.org/article/a865dc2f7c6c4ffc86c89c87f974b560

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Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling

Autor: Lenny Moise, Don Sobell, Ann E. Sluder, Timothy Brauns, S. Raju Paul, AS De Groot, Anja Garritsen, Richard A. Bowen, Anja Scholzen, Skylar Korek, J. Hess, Patrick Reeves, Laurie A. Baeten, Mark C. Poznansky, Y. Yi

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Scientific Reports

Q-fever is a flu-like illness caused by Coxiella burnetii (Cb), a highly infectious intracellular bacterium. There is an unmet need for a safe and effective vaccine for Q-fever. Correlates of immune protection to Cb infection are limited. We proposed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf26cd9496df33e4e3e0e4391766f6b3
http://link.springer.com/article/10.1038/s41598-020-69327-x

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A pilot clinical trial of a near‐infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking

Autor: Jeffrey A. Gelfand, Brent R. Martin, Yoshifumi Kimizuka, Satoshi Kashiwagi, Timothy Brauns, Elliot L. Botvinick, Mark C. Poznansky, Kristen Elkins, Kristen M. Kelly, Joseph J. Locascio, Rosalynn M. Nazarian, Blair Parry, Logan W Thomas, Skylar Korek

Publikováno v: Gelfand, JA; Nazarian, RM; Kashiwagi, S; Brauns, T; Martin, B; Kimizuka, Y; et al.(2018). A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, fj201801095R. doi: 10.1096/fj.201801095r. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5v0817vt

Many vaccines require adjuvants to enhance immunogenicity, but there are few safe and effective intradermal (i.d.) adjuvants. Murine studies have validated the potency of laser illumination of skin as an adjuvant for i.d. vaccination with advantages

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb3102758ad0944e880d4ba7dd1fcce
https://doi.org/10.1096/fj.201801095r

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Non-small cell lung cancer: Analysis using mass cytometry and next generation sequencing reveals new opportunities for the development of personalized therapies

Publikováno v: Journal of Clinical Oncology. 38:e21026-e21026

e21026 Background: Comprehensive molecular profiling and the use of biomarkers as companion diagnostics have transformed precision medicine for cancer patients. To identify patient-specific tumor microenvironment and biomarker profiles, we assessed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::521cab08a966f6510ff70b28cb0682fc
https://doi.org/10.1200/jco.2020.38.15_suppl.e21026

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