Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Skye R Rudiger"'
Autor:
Victoria J Sugrue, Joseph Alan Zoller, Pritika Narayan, Ake T Lu, Oscar J Ortega-Recalde, Matthew J Grant, C Simon Bawden, Skye R Rudiger, Amin Haghani, Donna M Bond, Reuben R Hore, Michael Garratt, Karen E Sears, Nan Wang, Xiangdong William Yang, Russell G Snell, Timothy A Hore, Steve Horvath
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/3a91ff2b152a430ebb04aa6413d17d2f
Autor:
Victoria J Sugrue, Joseph Alan Zoller, Pritika Narayan, Ake T Lu, Oscar J Ortega-Recalde, Matthew J Grant, C Simon Bawden, Skye R Rudiger, Amin Haghani, Donna M Bond, Reuben R Hore, Michael Garratt, Karen E Sears, Nan Wang, Xiangdong William Yang, Russell G Snell, Timothy A Hore, Steve Horvath
Publikováno v:
eLife, Vol 10 (2021)
In mammals, females generally live longer than males. Nevertheless, the mechanisms underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful biological biomarkers capable of precisely estimating chronological age and
Externí odkaz:
https://doaj.org/article/901ed9d95cff4307a781c381e14cdfb3
Autor:
Stephen J Sawiak, Sunthara Rajan Perumal, Skye R Rudiger, Loren Matthews, Nadia L Mitchell, Clive J McLaughlan, C Simon Bawden, David N Palmer, Timothy Kuchel, A Jennifer Morton
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132331 (2015)
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN6. It is a recessive genetic lysosomal storage disease characterised by progressive neurodegeneration. It starts insidiously and leads to blindness, e
Externí odkaz:
https://doaj.org/article/78c65da609e144239b190d058504b085
Autor:
James A. Armitage, Janna L. Morrison, Geoffrey A. Head, Skye R. Rudiger, David O. Kleemann, Monalisa Padhee, Jack R. T. Darby, Jennifer M. Kelly, Simon K. Walker, Song Zhang, I. Caroline McMillen, Severence M. MacLaughlin
Publikováno v:
Journal of Developmental Origins of Health and Disease. 12:731-737
Nutrition during the periconceptional period influences postnatal cardiovascular health. We determined whether in vitro embryo culture and transfer, which are manipulations of the nutritional environment during the periconceptional period, dysregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731e528dfee338f8731c991173bfe009
https://doi.org/10.1017/s2040174420001014
https://doi.org/10.1017/s2040174420001014
Autor:
Richard L.M. Faull, John F. Pearson, James F. Gusella, Rudiger Brauning, Clive J. McLaughlan, Stefano Patassini, Skye R. Rudiger, Benjamin T Day, Paul S. MacLean, Richard D. Unwin, Garth J. S. Cooper, Emily R Mears, Paul J. Verma, Henry J. Waldvogel, Simon C Bawden, Suzanne J. Reid, Marcy E. MacDonald, Matthew J Grant, Renee R. Handley, Russell G. Snell
Publikováno v:
Journal of Huntington's Disease
Background: The pathological mechanism of cellular dysfunction and death in Huntington’s disease (HD) is not well defined. Our transgenic HD sheep model (OVT73) was generated to investigate these mechanisms and for therapeutic testing. One particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08657a0a43b835bb449c5a0dde17f5
https://pubmed.ncbi.nlm.nih.gov/34420978
https://pubmed.ncbi.nlm.nih.gov/34420978
Autor:
Joseph A. Zoller, Ake T. Lu, Victoria J Sugrue, Donna M. Bond, Russell G. Snell, Karen E. Sears, Oscar Ortega-Recalde, Michael Garratt, Steve Horvath, Pritika Narayan, Amin Haghani, Nan Wang, Reuben R Hore, Skye R. Rudiger, Timothy A. Hore, C. Simon Bawden, Matthew J Grant, Xiangdong William Yang
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
In mammals, females generally live longer than males. Nevertheless, the mechanisms underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful biological biomarkers capable of precisely estimating chronological age and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14806c2a1552708f76451eaecf4a3fc
https://elifesciences.org/articles/64932
https://elifesciences.org/articles/64932
Autor:
Gordon S. Howarth, Skye R. Rudiger, Russell G. Snell, C.S. Bawden, N. Siva Subramaniam, Richard L.M. Faull, Roger Yazbeck
Publikováno v:
International Journal of Mass Spectrometry. 442:102-108
The 13C-labelled methionine breath test is a non-invasive test with the potential to evaluate metabolic liver mitochondrial dysfunction in vivo. This study aimed to develop an optimised protocol for breath collection in sheep and compare 13C-methioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::958e0b302008ca9e58613b07832fb210
https://doi.org/10.1016/j.ijms.2019.05.011
https://doi.org/10.1016/j.ijms.2019.05.011
Autor:
Henry J. Waldvogel, Richard L.M. Faull, Samantha J. Murray, Russell G. Snell, Brittney L. Black, Suzanne J. Reid, Skye R. Rudiger, C. Simon Bawden
Publikováno v:
Journal of Chemical Neuroanatomy. 97:43-56
The substantia nigra is an integral component of the basal ganglia circuitry for limbic and motor functions. Dysfunction and degeneration of the basal ganglia are fundamental aspects of neurodegenerative diseases such as Parkinson's disease and Hunti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1995a77d41bf1d729436ed4e9fb4c11c
https://doi.org/10.1016/j.jchemneu.2019.01.007
https://doi.org/10.1016/j.jchemneu.2019.01.007
Autor:
Nan Wang, Reuben R Hore, Michael Garratt, Skye R. Rudiger, C. Simon Bawden, Donna M. Bond, Pritika Narayan, Karen E. Sears, Matthew J Grant, Steve Horvath, Amin Haghani, Joseph A. Zoller, Xiangdong William Yang, Russell G. Snell, Ake T. Lu, Oscar Ortega-Recalde, Timothy A. Hore, Victoria J Sugrue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b9064d7c607f40b8d618609ff2a8f3
https://doi.org/10.7554/elife.64932.sa2
https://doi.org/10.7554/elife.64932.sa2
Autor:
Steve Horvath, Joseph A. Zoller, Donna M. Bond, Xia Yang, Skye R. Rudiger, Karen E. Sears, Timothy A. Hore, C.S. Bawden, Oscar Ortega-Recalde, Victoria J Sugrue, Matthew J Grant, Pritika Narayan, Amin Haghani, Nan Wang, Ake T. Lu, Russell G. Snell, Michael Garratt
SUMMARYIn mammals, females generally live longer than males. Nevertheless, the mechanisms underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful biological biomarkers capable of precisely estimating chronological a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb116ac38c73332ebd9811f0bc4cd707
https://doi.org/10.1101/2020.11.16.385369
https://doi.org/10.1101/2020.11.16.385369