Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sky W. Brubaker"'
Autor:
Sky W. Brubaker, Isabella R. Walters, Emily M. Hite, Lorena R. Antunez, Emma L. Palm, Hans H. Funke, Bryan L. Steadman
Publikováno v:
Vaccines, Vol 12, Iss 7, p 761 (2024)
Many vaccines require multiple doses for full efficacy, posing a barrier for patient adherence and protection. One solution to achieve full vaccination may be attained with single-administration vaccines containing multiple controlled release doses.
Externí odkaz:
https://doaj.org/article/f2e421d3bef147e388480d33a7ca911b
Autor:
Lindsay J. Wheeler, Zachary L. Watson, Lubna Qamar, Tomomi M. Yamamoto, Brandon T. Sawyer, Kelly D. Sullivan, Santosh Khanal, Molishree Joshi, Veronique Ferchaud-Roucher, Harry Smith, Lauren A. Vanderlinden, Sky W. Brubaker, Cecilia M. Caino, Hyunmin Kim, Joaquin M. Espinosa, Jennifer K. Richer, Benjamin G. Bitler
Publikováno v:
iScience, Vol 19, Iss , Pp 474-491 (2019)
Summary: High-grade serous ovarian cancers (HGSOCs) arise from exfoliation of transformed cells from the fallopian tube, indicating that survival in suspension, and potentially escape from anoikis, is required for dissemination. We report here the re
Externí odkaz:
https://doaj.org/article/d7cae58c70cf4b989ef74c7cfa5a6c7f
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101612- (2020)
Summary: In mammalian cells, inflammatory caspases detect Gram-negative bacterial invasion by binding lipopolysaccharides (LPS). Murine caspase-11 binds cytosolic LPS, stimulates pyroptotic cell death, and drives sepsis pathogenesis. Extracellular pr
Externí odkaz:
https://doaj.org/article/9992037b93404f248604bca481d41fd8
Autor:
Susan M Brewer, Christian Twittenhoff, Jens Kortmann, Sky W Brubaker, Jared Honeycutt, Liliana Moura Massis, Trung H M Pham, Franz Narberhaus, Denise M Monack
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009345 (2021)
Sensing and responding to environmental signals is critical for bacterial pathogens to successfully infect and persist within hosts. Many bacterial pathogens sense temperature as an indication they have entered a new host and must alter their virulen
Externí odkaz:
https://doaj.org/article/8f62b9078829477481fd855919477671
Autor:
Jared D Honeycutt, Nicolas Wenner, Yan Li, Susan M Brewer, Liliana M Massis, Sky W Brubaker, Phoom Chairatana, Siân V Owen, Rocío Canals, Jay C D Hinton, Denise M Monack
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008763 (2020)
The various sub-species of Salmonella enterica cause a range of disease in human hosts. The human-adapted Salmonella enterica serovar Typhi enters the gastrointestinal tract and invades systemic sites to cause enteric (typhoid) fever. In contrast, mo
Externí odkaz:
https://doaj.org/article/3ea3abb68269426eb3b643d041618104
Autor:
Magdalena Matusiak, John W. Hickey, Bogdan Luca, Guolan Lu, Lukasz Kidzinski, Shirley Shu, Deana Rae Crystal Colburg, Darci J. Phillips, Sky W. Brubaker, Gregory W. Charville, Jeanne Shen, Garry P. Nolan, Aaron M. Newman, Robert B. West, Matt van de Rijn
SummaryMacrophages are the most abundant immune cell type in the tumor microenvironment (TME). Yet the spatial distribution and cell interactions that shape macrophage function are incompletely understood. Here we use single-cell RNA sequencing data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa4a4ae8c952c8e49bcb89dbd8efe3c6
https://doi.org/10.1101/2022.08.18.504434
https://doi.org/10.1101/2022.08.18.504434
Publikováno v:
Current Opinion in Immunology. 60:63-70
Inflammasomes are a formidable armada of intracellular pattern recognition receptors. They recognize determinants of infection, such as foreign entities or danger signals within the host cell cytosol, rapidly executing innate immune defenses and init
Autor:
Liliana M. Massis, Sky W. Brubaker, Trung H.M. Pham, Denise M. Monack, Christian Twittenhoff, Jens Kortmann, Jared Honeycutt, Susan M. Brewer, Franz Narberhaus
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009345 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009345 (2021)
Sensing and responding to environmental signals is critical for bacterial pathogens to successfully infect and persist within hosts. Many bacterial pathogens sense temperature as an indication they have entered a new host and must alter their virulen
Autor:
Yan Li, Phoom Chairatana, Nicolas Wenner, Jay C. D. Hinton, Sky W. Brubaker, Denise M. Monack, Jared Honeycutt, Liliana M. Massis, Rocío Canals, Siân V. Owen, Susan M. Brewer
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 8, p e1008763 (2020)
PLoS Pathogens, Vol 16, Iss 8, p e1008763 (2020)
The various sub-species of Salmonella enterica cause a range of disease in human hosts. The human-adapted Salmonella enterica serovar Typhi enters the gastrointestinal tract and invades systemic sites to cause enteric (typhoid) fever. In contrast, mo
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 12, p e1005863 (2017)
PLoS computational biology, vol 13, iss 12
Botham, Crystal M; Arribere, Joshua A; Brubaker, Sky W; & Beier, Kevin T. (2017). Ten simple rules for writing a career development award proposal. PLOS COMPUTATIONAL BIOLOGY, 13(12), e1005863. doi: 10.1371/journal.pcbi.1005863. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7f84m121
PLoS Computational Biology, Vol 13, Iss 12, p e1005863 (2017)
PLoS computational biology, vol 13, iss 12
Botham, Crystal M; Arribere, Joshua A; Brubaker, Sky W; & Beier, Kevin T. (2017). Ten simple rules for writing a career development award proposal. PLOS COMPUTATIONAL BIOLOGY, 13(12), e1005863. doi: 10.1371/journal.pcbi.1005863. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7f84m121
Career development awards support intensive training and provide valuable funding for promising postdoctoral and/or junior faculty–level scientists during the transition to research independence. Therefore, career development awards are typically c