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Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial.

Autor: Syversen SW; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway., Goll GL; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway., Jørgensen KK; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway., Sandanger Ø; Section of Dermatology, Oslo University Hospital, Oslo, Norway., Sexton J; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway., Olsen IC; Department of Research Support for Clinical Trials, Oslo University Hospital, Oslo, Norway., Gehin JE; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Warren DJ; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Brun MK; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Klaasen RA; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Karlsen LN; Department of Gastroenterology, Stavanger University Hospital, Stavanger, Norway., Noraberg G; Department of Gastroenterology, Hospital of Southern Norway Trust, Arendal, Norway., Zettel C; Department of Rheumatology, Betanien Hospital, Skien, Norway., Ljoså MKA; Department of Rheumatology, Ålesund Hospital, Ålesund, Norway., Haugen AJ; Department of Rheumatology, Østfold Hospital Trust, Moss, Norway., Njålla RJ; Department of Rheumatology, Nordland Hospital Trust, Bodø, Norway., Bruun TJ; Department of Rheumatology, University Hospital of North Norway, Tromsø, Norway., Seeberg KA; Departement of Gastroenterology, Vestfold Hospital Trust, Tønsberg, Norway., Michelsen B; Division of Rheumatology, Department of Medicine, Hospital of Southern Norway Trust, Kristiansand, Norway., Strand EK; Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway., Skorpe S; Haugesund Hospital for Rheumatic Diseases, Haugesund, Norway., Blomgren IM; Department of Gastroenterology, Fonna Hospital Trust, Haugesund, Norway., Bragnes YH; Department of Rheumatology, Vestre Viken Hospital Trust, Drammen, Norway., Dotterud CK; Department of Dermatology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Thune T; Department of Dermatology, Haukeland University Hospital, Bergen, Norway., Ystrøm CM; Department of Medicine, Innlandet Hospital Trust, Elverum, Norway., Torp R; Department of Medicine, Innlandet Hospital Trust, Hamar, Norway., Mielnik P; Department of Neurology, Rheumatology, and Physical Medicine, Førde Hospital Trust, Førde, Norway., Mørk C; Akershus Dermatology Center, Lørenskog, Norway., Kvien TK; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Jahnsen J; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Bolstad N; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Haavardsholm EA; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway.

Publikováno v: JAMA [JAMA] 2021 May 04; Vol. 325 (17), pp. 1744-1754.