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Background: Tumour-associated lymphocytes (TALs) present in effusions of ovarian cancer patients exhibit impaired activities, due to the immunosuppressive environment of the ascites. Means to enhance their cytotoxicity against autologous tumour cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::22746a7dfde4413d702b1263aa816ea5
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088332
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088332
Prothymosin α (ProTα) is a small acidic polypeptide with important immunostimulatory properties, which we have previously shown to be exerted by its carboxyl (C)-terminus. It exerts immunoenhancing effects through stimulation of monocytes via toll-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::ccc4b34bcea90b59032469a1749dfd38
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3004405
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3004405
Phenoxodiol (PXD) is a synthetic analogue of the plant isoflavone genistein with improved anticancer efficacy. Various properties and mechanisms of action have been attributed to the drug, the most important being its ability to sensitize resistant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::38fe347b3258ceb21e5d0dd46910fbb2
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3089991
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3089991
Prothymosin alpha (ProTα) is an acidic polypeptide associated both with cell proliferation and immune regulation. Although ProTα's immunomodulating activity is well established at cellular level, limited information is available regarding the signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::85b288c4a38599a5a1e4d109c0ee7507
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094986
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094986
From the aerial parts of Marrubium cylleneum, one labdane nor-diterpene has been isolated together with two labdane diterpenes, hitherto not known as natural products. The structures of the isolated compounds were established by means of NMR [1H-1H-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::86fc306e3c90b105da15f90aec010276
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3010494
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3010494
Since conserved mammalian polypeptides are believed to exhibit enhanced immunogenicity in avian species, hens were immunized against the poorly immunogenic, highly conserved mammalian polypeptide prothymosin alpha (ProTα), i.e. against either non-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::cd324649b6cbcbb3b6bf83f996d2f773
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996149
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2996149
Prothymosin α (proTα) is a 109 amino acid long polypeptide presenting distinct immunoenhancing activity in vitro and in vivo. Recent reports suggest that in apoptotic cells, proTα is cleaved by caspases at its carboxy(C)-terminus generating potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::f7b2082085f30ef8fe80fbc034e2ad15
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3004668
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3004668