Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase

Autor: Amstrup, Søren Kirk, Sofos, Nicholas Egholm, Karlsen, Jesper Lykkegaard, Skjerning, Ragnhild Bager, Boesen, Thomas, Enghild, Jan Johannes, Hove-Jensen, Bjarne, Brodersen, Ditlev E.

Publikováno v: Amstrup, S K, Sofos, N E, Karlsen, J L, Skjerning, R B, Boesen, T, Enghild, J J, Hove-Jensen, B & Brodersen, D E 2022 ' Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase ' bioRxiv . https://doi.org/10.1101/2022.06.09.495270

Phosphorus is an essential macronutrient for all microorganisms and can be extracted from the environment by several metabolic pathways. In Escherichia coli, the 14-cistron phn operon encoding the carbon-phosphorus (C-P) lyase enzymatic machinery all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::fc73dd03b1b180b13a2f5616e1780fe4
https://pure.au.dk/portal/da/publications/structural-remodelling-of-the-carbonphosphorus-lyase-machinery-by-a-dual-abc-atpase(e2f87185-df40-431c-a919-568390fd87d8).html

The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD+

Autor: Skjerning, Ragnhild Bager, Senissar, Meriem, Winther, Kristoffer S., Gerdes, Kenn, Brodersen, Ditlev E.

Publikováno v: Skjerning, R B, Senissar, M, Winther, K S, Gerdes, K & Brodersen, D E 2019, ' The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD + ', Molecular Microbiology, vol. 111, no. 1, pp. 221-236 . https://doi.org/10.1111/mmi.14150

Type II toxin-antitoxin (TA) modules, which are important cellular regulators in prokaryotes, usually encode two proteins, a toxin that inhibits cell growth and a nontoxic and labile inhibitor (antitoxin) that binds to and neutralizes the toxin. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::52fe230cc1b78a31fe765579f39646a9
https://pure.au.dk/portal/da/publications/the-res-domain-toxins-of-resxre-toxinantitoxin-modules-induce-cell-stasis-by-degrading-nad(bfb63eb2-cdb8-422f-8d0d-01f560a821c3).html

The RES domain toxins of RES‐Xre toxin‐antitoxin modules induce cell stasis by degrading NAD⁺.

Autor: Skjerning, Ragnhild Bager¹, Senissar, Meriem², Winther, Kristoffer S.¹, Gerdes, Kenn¹ kgerdes@bio.ku.dk, Brodersen, Ditlev E.² DEB@mbg.au.dk

Publikováno v: Molecular Microbiology. Jan2019, Vol. 111 Issue 1, p221-236. 16p. 1 Black and White Photograph, 3 Diagrams, 2 Charts, 2 Graphs.

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