Výsledky vyhledávání - "Skjalg Bruheim"

Akademický článek

Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array.

Autor: Bin Wang, Paul Howel, Skjalg Bruheim, Jingfang Ju, Laurie B Owen, Oystein Fodstad, Yaguang Xi

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17167 (2011)

BACKGROUND: A number of gene-profiling methodologies have been applied to microRNA research. The diversity of the platforms and analytical methods makes the comparison and integration of cross-platform microRNA profiling data challenging. In this stu

Externí odkaz: https://doaj.org/article/cf5c4edfd179409aac19802f19e3a91f

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Data from Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide

Autor: Oystein Fodstad, Jingfang Ju, Yaguang Xi, Skjalg Bruheim

Purpose: In osteosarcoma, aggressive preoperative and postoperative multidrug chemotherapy given to all patients has improved patient survival rate to the present level of ∼60%. However, no tumor marker is available that reliably can identify those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37157787ebfd11d41f34a2ab38be8098
https://doi.org/10.1158/1078-0432.c.6517989

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Supplementary Data from Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide

Autor: Oystein Fodstad, Jingfang Ju, Yaguang Xi, Skjalg Bruheim

Supplementary Data from Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601a347342b07237c3cf7794881df277
https://doi.org/10.1158/1078-0432.22440690.v1

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The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo

Autor: Zenhe Suo, Torunn Wendel, Skjalg Bruheim, Yan Zhen, Antoni Wiedlocha

Publikováno v: Experimental Cell Research. 340:220-226

HSP90 is a molecular chaperone essential for stability, activity and intracellular sorting of many proteins, including oncoproteins, such as tyrosine kinases, transcription factors and cell cycle regulatory proteins. Therefore, inhibitors of HSP90 ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a07522d3bb0cc1deafb48e6521c83d4
https://doi.org/10.1016/j.yexcr.2015.12.017

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Radiosynthesis and Biodistribution of a Prosthetic Group (18F-FENMA) Conjugated to Cyclic RGD Peptides

Autor: Dag Erlend Olberg, Joseph M Arukwe, Ole Kristian Hjelstuen, Alan Cuthbertson, Alexandr Kristian, Magne Solbakken, Skjalg Bruheim, Hong Qu

Publikováno v: Bioconjugate Chemistry. 21:2297-2304

We have recently reported a new N-methylaminooxy-based prosthetic group for the site-selective introduction of ¹⁸F-fluorine under mild acidic aqueous conditions into model peptides functionalized with a Michael acceptor moiety. To further investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::073f13b25752e10071a797e5dcf34cc4
https://doi.org/10.1021/bc1003229

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Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide

Autor: Jingfang Ju, Øystein Fodstad, Skjalg Bruheim, Yaguang Xi

Publikováno v: Clinical Cancer Research. 15:7161-7169

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd705dd84d9630d1efb81ce512ccc4d
https://doi.org/10.1158/1078-0432.ccr-08-2816

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Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

Autor: Marko Kornmann, Galina I. Botchkina, Elaine Gavin, Yu Wan, Kenji Kudo, Yuan Wang, Jingfang Ju, Bo Song, Skjalg Bruheim, Øystein Fodstad, Yaguang Xi, Andrea Formentini

Publikováno v: Oncogene

In this study, our high throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts. Tumor cells ectopically transfected with miR-140 were more resistan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ff9977a5709bb41ff9d5a19caa8eda
https://doi.org/10.1038/onc.2009.274

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VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis

Autor: Taro Matsumoto, Peetra U. Magnusson, Hideo Mugishima, Skjalg Bruheim, Tone Berge, Jiong Wu, Debrabata Mukhopadhyay, Johan Dixelius, Svante Bohman, Christer Wernstedt, Charlotte Wikner, Anne Spurkland, Anna Dimberg, Lena Claesson-Welsh, Ling Wang, Jian Hua Qi

Publikováno v: The EMBO Journal. 24:2342-2353

Vascular endothelial growth factor receptor-2 (VEGFR-2) activation by VEGF-A is essential in vasculogenesis and angiogenesis. We have generated a pan-phosphorylation site map of VEGFR-2 and identified one major tyrosine phosphorylation site in the ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f760af25209c97d2feb69e6761acc5d9
https://doi.org/10.1038/sj.emboj.7600709

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Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts

Autor: Skjalg, Bruheim, Marit Liland, Sandvold, Gunhild M, Mælandsmo, Oystein, Fodstad

Publikováno v: Anticancer research. 33(9)

The objective of the present study was to determine the in vivo antitumor activity of elacytarabine, the 5'-elaidic acid ester of arabinofuranosyl cytidine, alone and in combination with bevacizumab, cetuximab and trastuzumab in Vascular endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3aa30296f8adf859ebb30455aad5a34b
https://pubmed.ncbi.nlm.nih.gov/24023287

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Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models

Autor: P. Noordhuis, Finn Myhren, Marit Liland Sandvold, Jan Balzarini, Godefridus J. Peters, Iduna Fichtner, H.R. Hendriks, Skjalg Bruheim, Øystein Fodstad, Andries M. Bergman, A.D. Adema

Publikováno v: Investigational New Drugs 29 (3): 456-466.
Bergman, A M, Adema, A D, Balzarini, J, Bruheim, S, Fichtner, I, Noordhuis, P, Fodstad, O, Myhren, F, Sandvold, ML, Hendriks, H R & Peters, G J 2011, ' Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models ', Investigational New Drugs, vol. 29, no. 3, pp. 456-466 . https://doi.org/10.1007/s10637-009-9377-7
Investigational New Drugs, 29(3), 456-466. Kluwer Academic Publishers
Investigational New Drugs

Gemcitabine is a deoxycytidine (dCyd) analog with activity in leukemia and solid tumors, which requires phosphorylation by deoxycytidine kinase (dCK). Decreased membrane transport is a mechanism of resistance to gemcitabine. In order to facilitate ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056d526cd05cb47e783e10a0de43dc96
https://lirias.kuleuven.be/handle/123456789/306289

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