Clinical Study of Fetal Mesencephalic Intracerebral Transplants for the Treatment of Parkinson's Disease

Autor: Oleg V. Kopyov Ph.D., M.D., Deane “Skip” Jacques, Abraham Lieberman, Christopher M. Duma, Robert L. Rogers

Publikováno v: Cell Transplantation, Vol 5 (1996)

This study reports our findings from 22 patients (ages ranging from 42 to 73 yr; mean = 55.2) with recalcitrant idiopathic Parkinson's disease (PD) who received implants of fetal ventral mesencephalic tissue using an MRI-guided stereotactic procedure

Externí odkaz: https://doaj.org/article/566d75cf4c594fc5809d0ac5448a3f3a

The Treatment of Movement Disorders Using Gamma Knife Stereotactic Radiosurgery

Autor: Christopher Duma, Oleg V. Kopyov, Deane 'skip' Jacques

Publikováno v: Neurosurgery Clinics of North America. 10:379-389

In this era of modern neurosurgery, we are able to provide adequate amelioration of disabling symptoms for the small subset of patients who have conditions that may make them unacceptable candidates for invasive stereotactic neurosurgical interventio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::715b9993a8a31b2d4ddc8946e6a56b9a
https://doi.org/10.1016/s1042-3680(18)30202-x

Outcome Following Intrastriatal Fetal Mesencephalic Grafts for Parkinson's Patients Is Directly Related to the Volume of Grafted Tissue

Autor: Christopher M. Duma, Deane 'skip' Jacques, Abraham Lieberman, Robert L. Rogers, Oleg V. Kopyov

Publikováno v: Experimental Neurology. 146:536-545

The effect of varying the volume of grafted fetal mesencephalic tissue was studied in patients with idiopathic Parkinson's disease in a single-blinded study. Evaluations were performed according to the Core Assessment Program for Intracerebral Transp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a6ed5925f5349b6636b5ac0990788e
https://doi.org/10.1006/exnr.1997.6577

Immunohistochemical Detection and Correlation Between MHC Antigen and Cell-mediated Immune System in Recurrent Glioma by APAAP Method

Autor: Hunter Sheldon, G. B. Techy, Koichi Miyagi, Donald B. Freshwater, Marylou Ingram, Dean B. Skip Jacques

Publikováno v: Neurologia medico-chirurgica. 30:649-655

As part of an on-going clinical trial of immunotherapy for recurrent malignant gliomas, using alkaline phosphatase-anti-alkaline phosphatase method with monoclonal antibodies, we investigated the correlation between expression of the major histocompa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c715fc81e307db8adbd0fae594329e75
https://doi.org/10.2176/nmc.30.649

Therapy of recurrent high grade gliomas with surgery, and autologous mitogen activated IL-2 stimulated killer (MAK) Lymphocytes: I. Enhancement of MAK lytic activity and cytokine production by PHA and clinical use of PHA

Autor: Gale A. Granger, Skip Jacques, Yancey B. Beamer, Judy S. Coss, Bharathi Vayuvegula, Robert S. Yamamoto, Randy S. Silberman, Edward W. B. Jeffes, Sudhir Gupta

Publikováno v: Jeffes, EWB; Beamer, YB; Jacques, S; Silberman, RS; Vayuvegula, B; Gupta, S; et al.(1993). Therapy of recurrent high grade gliomas with surgery, and autologous mitogen activated IL-2 stimulated killer (MAK) Lymphocytes: I. Enhancement of MAK lytic activity and cytokine production by PHA and clinical use of PHA. Journal of Neuro-Oncology, 15(2), 141-155. doi: 10.1007/BF01053935. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1p41f9ss

Nineteen patients with recurrent high grade gliomas were treated in a phase I/II trial with aggressive debulking of the tumor, mitogen activated IL-2 stimulated peripheral blood lymphocytes (MAK cells), and rIL-2. Phytohemagglutin (PHA) was introduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdbd01f805d761b4a46799d46c89426
http://www.escholarship.org/uc/item/1p41f9ss