Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Skin and Connective Tissue Diseases::Connective Tissue Diseases::Scleroderma, Systemic [DISEASES]"'
Autor:
Gonzalo Villanueva-Martin, Marialbert Acosta-Herrera, Martin Kerick, Elena López-Isac, Carmen P. Simeón, José L. Callejas, Shervin Assassi, Lorenzo Beretta, International SSc Group, Australian Scleroderma Interest Group (ASIG), Yannick Allanore, Susanna M. Proudman, Mandana Nikpour, Carmen Fonseca, Christopher P. Denton, Timothy R. D. J. Radstake, Maureen D. Mayes, Xia Jiang, Javier Martin, Lara Bossini-Castillo
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 20; Pages: 6014
Scientia
Scientia
Obesity contributes to a chronic proinflammatory state, which is a known risk factor to develop immune-mediated diseases. However, its role in systemic sclerosis (SSc) remains to be elucidated. Therefore, we conducted a two-sample mendelian randomiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856128eea4154bcf6a879625be3831a5
https://www.mdpi.com/2077-0383/11/20/6014/pdf?version=1666753836
https://www.mdpi.com/2077-0383/11/20/6014/pdf?version=1666753836
Autor:
Kerick, Martin, Acosta-Herrera, Marialbert, Simeón-Aznar, Carmen Pilar, Callejas, José Luis, Assassi, Shervin, International SSc Group, Proudman, Susanna M, Nikpour, Mandana, Australian Scleroderma Interest Group (ASIG), PRECISESADS Clinical Consortium, Hunzelmann, Nicolas, Moroncini, Gianluca, de Vries-Bouwstra, Jeska K, Orozco, Gisela, Barton, Anne, Herrick, Ariane L, Terao, Chikashi, Allanore, Yannick, Fonseca, Carmen, Alarcón-Riquelme, Marta Eugenia, Radstake, Timothy R D J, Beretta, Lorenzo, Denton, Christopher P, Mayes, Maureen D, Martin, Javier
Publikováno v:
NPJ Genomic Medicine, 7, 1
International SSc Group, Australian Scleroderma Interest Group (ASIG) & PRECISESADS Clinical Consortium 2022, ' Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis ', NPJ GENOMIC MEDICINE, vol. 7, no. 1, 57 . https://doi.org/10.1038/s41525-022-00327-8
Scientia
NPJ Genomic Medicine, 7
NPJ GENOMIC MEDICINE, 7(1):57. Nature Publishing Group
International SSc Group, Australian Scleroderma Interest Group (ASIG) & PRECISESADS Clinical Consortium 2022, ' Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis ', NPJ GENOMIC MEDICINE, vol. 7, no. 1, 57 . https://doi.org/10.1038/s41525-022-00327-8
Scientia
NPJ Genomic Medicine, 7
NPJ GENOMIC MEDICINE, 7(1):57. Nature Publishing Group
Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K CN were an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c515a057db2ca1f215e35ef1d803d2
https://hdl.handle.net/10481/77756
https://hdl.handle.net/10481/77756
Autor:
Carbonell, Cristina, Marcos, Miguel, Guillén-Del-Castillo, Alfredo, Rubio-Rivas, Manuel, Argibay, Ana, Marín-Ballvé, Adela, Rodríguez-Pintó, Ignasi, Baldà-Masmiquel, Maria, Callejas-Moraga, Eduardo, Colunga, Dolores, Sáez-Comet, Luis, González-Echávarri, Cristina, Ortego-Centeno, Norberto, Marí-Alfonso, Begoña, Vargas-Hitos, José-Antonio, Todolí-Parra, José-Antonio, Trapiella, Luis, Herranz-Marín, María-Teresa, Freire, Mayka, Castro-Salomó, Antoni, Perales-Fraile, Isabel, Madroñero-Vuelta, Ana-Belén, Sánchez-García, María-Esther, Ruiz-Muñoz, Manuel, González-García, Andrés, Sánchez-Redondo, Jorge, de-la-Red-Bellvis, Gloria, Fernández-Luque, Alejandra, Muela-Molinero, Alberto, Lledó, Gema-María, Tolosa-Vilella, Carles, Fonollosa-Pla, Vicent, Chamorro, Antonio-Javier, Simeón-Aznar, Carmen-Pilar, RESCLE Investigators, Autoimmune Diseases Study Group (GEAS)
Publikováno v:
AUTOIMMUNITY REVIEWS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Scientia
Dipòsit Digital de la UB
Universidad de Barcelona
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Scientia
Dipòsit Digital de la UB
Universidad de Barcelona
Anticentromere antibody; Cancer; Systemic sclerosis Anticuerpo anticentrómero; Cáncer; Esclerosis sistémica Anticòs anticentròmer; Càncer; Esclerosi sistèmica Aim Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915cb2dbf0ab99c6add8025007f87455
http://zaguan.unizar.es/record/121055
http://zaguan.unizar.es/record/121055
Autor:
Guillén-Del-Castillo, Alfredo, Meseguer, Manuel López, Fonollosa-Pla, Vicent, Sáez Giménez, Berta, Colunga-Argüelles, Dolores, Revilla-López, Eva, Rubio-Rivas, Manuel, Ropero, Maria José Cristo, Argibay, Ana, Barberá, Joan Albert, Pla Salas, Xavier, Martínez Meñaca, Amaya, Madroñero Vuelta, Ana Belén, Lara Padrón, Antonio, Sáez Comet, Luis, Domingo Morera, Juan Antonio, González-Echávarri, Cristina, Mombiela, Teresa, Ortego-Centeno, Norberto, Marín González, Manuela, Tolosa-Vilella, Carles, Blanco, Isabel, Escribano Subías, Pilar, Simeón-Aznar, Carmen Pilar, Aurtenetxe Pérez, Águeda, Barrios Garrido-Lestache, Elvira, Bedate Díaz, Pedro, Cifrián, José Manuel, Cristo Ropero, Maria Jose, Dos Subirá, Laura, Elías Hernández, Teresa, García Hernández, Francisco José, Carbonell, Juan Gil, Segovia, Ariadna González, Valverde, Tamara Hermida, Baldomero, Idaira Fámara Hernández, Hernández-González, Ignacio, Huertas, Julia Herrero, Palomares, Luis Jara, Arjona, Josefa Jiménez, Padrón, Antonio Lara, Lázaro-Salvador, María, López-Ramón, Marta, López-Reyes, Raquel, González, Manuela Marín, Meñaca, Amaya Martínez, Etxaniz, Francisco Javier Mazo, Velasco, Virginia Naranjo, Candelera, Remedios Otero, González, Isabel Otero, Lozano, Beatriz Rodríguez, Nieto, María Jesús Rodríguez, Soriano, Joaquín Rueda, Giménez, Berta Sáez, Safont, Belén, Llinas, Ernest Sala, Sebastián, Laura, Cubero, Javier Segovia, Domenech, María Teresa Subirana, Masmiquel, Maria Baldà, Moraga, Eduardo Callejas, Chamorro, Antonio-J., Freire, Mayka, Guillén-del-Castillo, Alfredo, Marín, Maria Teresa Herranz, Vuelta, Ana Belén Madroñero, Ballvé, Adela Marín, Fernández, Melany Pestaña, Salas, Xavier Pla, Pintó, Ignasi Rodríguez, Comet, Luis Sáez, Cervelló, Gonzalo Salvador, Parra, José Antonio Todolí, Trapiella, Luis, Hitos, José Antonio Vargas, Marín, Adela (REHAP Consortium)
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Consejo Superior de Investigaciones Científicas (CSIC)
Scientia
Dipòsit Digital de la UB
Universidad de Barcelona
Universitat Autònoma de Barcelona
Scientific Reports
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Consejo Superior de Investigaciones Científicas (CSIC)
Scientia
Dipòsit Digital de la UB
Universidad de Barcelona
To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5958a42c72a1e6b39625928ff5294b
https://ddd.uab.cat/record/258149
https://ddd.uab.cat/record/258149
Autor:
Martina Gahlemann, Alfredo Guillén-Del-Castillo, Michael Kreuter, Salome R. Mack, Mandy Avis, Sven Wind, Kristell Marzin, Madelon C. Vonk
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics, 47, 1, pp. 81-89
European Journal of Drug Metabolism and Pharmacokinetics, 47, 81-89
European Journal of Drug Metabolism and Pharmacokinetics
Scientia
European Journal of Drug Metabolism and Pharmacokinetics, 47, 81-89
European Journal of Drug Metabolism and Pharmacokinetics
Scientia
Contains fulltext : 248967.pdf (Publisher’s version ) (Open Access) BACKGROUND AND OBJECTIVES: Nintedanib is a tyrosine kinase inhibitor approved for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD), idiopathic pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d885fd470f94326021448f10278f27b
Autor:
Marvin J. Fritzler, Chelsea Bentow, Lorenzo Beretta, Boaz Palterer, Janire Perurena-Prieto, Maria Teresa Sanz-Martínez, Alfredo Guillen-Del-Castillo, Ana Marín, Vicent Fonollosa-Pla, Eduardo Callejas-Moraga, Carmen Pilar Simeón-Aznar, Michael Mahler
Publikováno v:
Scientia
Autoantibodies; Interstitial lung disease; Systemic sclerosis Autoanticuerpos; Enfermedad pulmonar intersticial; Esclerosis sistémica Autoanticossos; Malaltia pulmonar intersticial; Esclerosi sistèmica Anti-nuclear (ANA) are present in approximatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650eef638b638356f72de8f881187866
https://doi.org/10.3390/diagnostics13071257
https://doi.org/10.3390/diagnostics13071257
Autor:
López-Isac, E., Acosta-Herrera, M., Kerick, M., Assassi, S., Satpathy, A.T., Granja, J., Mumbach, M.R., Beretta, L., Simeón, C.P., Carreira, P., Ortego-Centeno, N., Castellvi, I., Bossini-Castillo, L., Carmona, F.D., Orozco, G., Hunzelmann, N., Distler, J.H.W., Franke, A., Lunardi, C., Moroncini, G., Gabrielli, A., de Vries-Bouwstra, J., Wijmenga, C., Koeleman, B.P.C., Nordin, A., Padyukov, L., Hoffmann-Vold, A.-M., Lie, B., Ríos, R., Callejas, J.L., Vargas-Hitos, J.A., García-Portales, R., Camps, M.T., Fernández-Nebro, A., González-Escribano, M.F., García-Hernández, F.J., Castillo, M.J., Aguirre, M.A., Gómez-Gracia, I., Fernández-Gutiérrez, B., Rodríguez-Rodríguez, L., García de la Peña, P., Vicente, E., Andreu, J.L., Fernández de Castro, M., López-Longo, F.J., Martínez, L., Fonollosa, V., Guillén, A., Espinosa, G., Tolosa, C., Pros, A., Rodríguez-Carballeira, M., Narváez, F.J., Rubio-Rivas, M., Ortiz-Santamaría, V, Madroñero, A.B., González-Gay, M.A., Díaz, B., Trapiella, L., Sousa, A., Egurbide, M.V., Fanlo-Mateo, P., Sáez-Comet, L., Díaz, F., Hernández, V, Beltrán, E., Román-Ivorra, J.A., Grau E., Alegre-Sancho, J.J., Freire, M., Blanco-García, F.J., Oreiro, N., Witte, T., Kreuter, A., Riemekasten, G., Airó P., Magro, C., Voskuyl, A.E., Vonk, M.C., Hesselstrand, R., Proudman S., Stevens, W., Nikpour, M., Zochling, J., Sahhar, J., Roddy, J., Nash, P., Tymms, K., Rischmueller, M., Lester, S., Vyse, T., Herrick, A.L., Worthington, J., Denton C.P., Allanore, Y., Brown, M.A., Radstake, T.R.D.J., Fonseca, C., Chang H.Y., Mayes, M.D., Martin, J., European Scleroderma Group, Australian Scleroderma Interest Group (ASIG)
Publikováno v:
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
Digital.CSIC. Repositorio Institucional del CSIC
Orozco, G & Worthington, J 2019, ' GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways ', Nature Communications, vol. 10, 4955 . https://doi.org/10.1038/s41467-019-12760-y
Nat Commun . 2019 Oct 31;10(1):4955
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
RUC. Repositorio da Universidade da Coruña
López-Isac, E, Acosta-Herrera, M, Kerick, M, Assassi, S, Satpathy, A T, Granja, J, Mumbach, M R, Beretta, L, Simeón, C P, Carreira, P, Ortego-Centeno, N, Castellvi, I, Bossini-Castillo, L, Carmona, F D, Orozco, G, Hunzelmann, N, Distler, J R H W, Franke, A, Lunardi, C, Moroncini, G, Gabrielli, A, de Vries-Bouwstra, J, Wijmenga, C, Koeleman, B P C, Nordin, A, Padyukov, L, Hoffmann-Vold, A-M, Lie, B, Ríos, R, Callejas, J L, Vargas-Hitos, J A, García-Portales, R, Camps, M T, Fernández-Nebro, A, González-Escribano, M F, García-Hernández, F J, Castillo, M J, Aguirre, M A, Gómez-Gracia, I, Fernández-Gutiérrez, B, Rodríguez-Rodríguez, L, García de la Peña, P, Vicente, E, Andreu, J L, Fernández de Castro, M, López-Longo, F J, Martínez, L, Fonollosa,, Voskuyl, A E, European Scleroderma Group†, Australian Scleroderma Interest Group (ASIG) & Voskuyl, A E 2019, ' GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways ', Nature Communications, vol. 10, no. 1, 4955 . https://doi.org/10.1038/s41467-019-12760-y
Scientia
Nature Communications, 10(1):4955. Nature Publishing Group
NATURE COMMUNICATIONS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Nature Communications, 10(1). Nature Publishing Group
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
Digital.CSIC. Repositorio Institucional del CSIC
Orozco, G & Worthington, J 2019, ' GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways ', Nature Communications, vol. 10, 4955 . https://doi.org/10.1038/s41467-019-12760-y
Nat Commun . 2019 Oct 31;10(1):4955
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
RUC. Repositorio da Universidade da Coruña
López-Isac, E, Acosta-Herrera, M, Kerick, M, Assassi, S, Satpathy, A T, Granja, J, Mumbach, M R, Beretta, L, Simeón, C P, Carreira, P, Ortego-Centeno, N, Castellvi, I, Bossini-Castillo, L, Carmona, F D, Orozco, G, Hunzelmann, N, Distler, J R H W, Franke, A, Lunardi, C, Moroncini, G, Gabrielli, A, de Vries-Bouwstra, J, Wijmenga, C, Koeleman, B P C, Nordin, A, Padyukov, L, Hoffmann-Vold, A-M, Lie, B, Ríos, R, Callejas, J L, Vargas-Hitos, J A, García-Portales, R, Camps, M T, Fernández-Nebro, A, González-Escribano, M F, García-Hernández, F J, Castillo, M J, Aguirre, M A, Gómez-Gracia, I, Fernández-Gutiérrez, B, Rodríguez-Rodríguez, L, García de la Peña, P, Vicente, E, Andreu, J L, Fernández de Castro, M, López-Longo, F J, Martínez, L, Fonollosa,, Voskuyl, A E, European Scleroderma Group†, Australian Scleroderma Interest Group (ASIG) & Voskuyl, A E 2019, ' GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways ', Nature Communications, vol. 10, no. 1, 4955 . https://doi.org/10.1038/s41467-019-12760-y
Scientia
Nature Communications, 10(1):4955. Nature Publishing Group
NATURE COMMUNICATIONS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Nature Communications, 10(1). Nature Publishing Group
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-FISABIO. Repositorio Institucional de Producción Científica
Systemic sclerosis (SSc) is an autoimmune disease that shows one of the highest mortality rates among rheumatic diseases. We perform a large genome-wide association study (GWAS), and meta-analysis with previous GWASs, in 26,679 individuals and identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a10e7153ec16c30a2d998be1d40f8a7
https://doi.org/10.1038/s41467-019-12760-y
https://doi.org/10.1038/s41467-019-12760-y