Výsledky vyhledávání - "Skin Absorption/drug effects"

Self-assembled mPEG-hexPLA polymeric nanocarriers for the targeted cutaneous delivery of imiquimod

Autor: Robert Gurny, Yogeshvar N. Kalia, Michael Möller, Margaux Mignot, Maria Lapteva, Karine Mondon

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 142 (2019) pp. 553-562

mPEG-hexPLA micelles have shown their ability to improve delivery and cutaneous bioavailability of a wide range of poorly water soluble and lipophilic molecules. Although poorly water soluble, imiquimod (IMQ) is only moderately lipophilic and it was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1d875b5647f6f2389aae6e1fccac39
https://doi.org/10.1016/j.ejpb.2019.01.008

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Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters

Autor: Ingrid Lopes, Yogeshvar N. Kalia, André Rolim Baby, Francisco Mariano Neto, André Luis Máximo Daneluti, Maria Valéria Robles Velasco, Jivaldo do Rosário Matos, Nadia Ruscinc

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Pharmaceutics, Vol. 570 (2019) P. 118633

Avobenzone (AVO), oxybenzone (OXY), and octyl methoxycinnamate (OMC), are widely used UV filters. The aim of this study was to investigate the effect of incorporation in mesoporous silica (SBA-15) on their cutaneous deposition and permeation. Stick f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7ae15ac93be5b5ee1ed04324786585

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Ex vivo human skin permeation of methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI)

Autor: Nancy B. Hopf, Gregory Plateel, David Vernez, Philipp Spring, Aurélie Berthet

Publikováno v: Archives of Toxicology, vol. 91, no. 11, pp. 3529-3542

Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are biocides used in many types of products such as cosmetics, paints, and cleaning agents. Skin contact is often encountered when using these products. Although MCI and MI are strong a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff3070d99a1501338e59e33eb959cbd
https://serval.unil.ch/notice/serval:BIB_EC438990248F

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In Vitro and In Vivo evaluation of a hydrogel-based microneedle device for transdermal electro-modulated analgesia

Autor: Sunaina Indermun, Lisa C. du Toit, Girish Modi, Viness Pillay, Regina Luttge, Mershen Govender, Yahya E. Choonara, Pradeep Kumar

Publikováno v: Journal of Pharmaceutical Sciences, 106(4). Wiley

With a significant portion of the world suffering from chronic pain, the management and treatment of this condition still requires extensive research to successfully mobilize and functionalize its sufferers. This article details the in vitro and in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35be1b9e06bb7bde42c9865b69a04fd8
http://www.scopus.com/inward/record.url?scp=85010973253&partnerID=8YFLogxK

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Therapy of psoriasis in childhood and adolescence - a German expert consensus

Autor: Sticherling, Michael, Augustin, Matthias, Boehncke, Wolf-Henning, Christophers, Enno, Domm, Silja, Gollnick, Harald, Reich, Kristian, Mrowietz, Ulrich

Publikováno v: Journal der Deutschen Dermatologischen Gesellschaft, Vol. 9, No 10 (2011) pp. 815-823

Psoriasis of childhood shows an annual prevalence of 0.71 % and accordingly has to be regarded as a frequent chronic inflammatory skin disorder of this age. The impact on the quality of life as well as development of the afflicted children and their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27ad63ead1a4b7b9c7e16f2ea49d90cf
https://pubmed.ncbi.nlm.nih.gov/21585653

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Water-filtered infrared-A (wIRA) can act as a penetration enhancer for topically applied substances

Autor: Otberg, N, Grone, D, Meyer, L, Schanzer, S, Hoffmann, G, Ackermann, H, Sterry, W, Lademann, J

Publikováno v: GMS German Medical Science, Vol 6, p Doc08 (2008)
GMS German Medical Science
GMS German Medical Science; VOL: 6; DOC08 /20080721/

Background: Water-filtered infrared-A (wIRA) irradiation has been shown to enhance penetration of clinically used topically applied substances in humans through investigation of functional effects of penetrated substances like vasoconstriction by cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c5fcbcdd0db960a14116a11f36dae475
http://www.egms.de/en/gms/2008-6/000053.shtml

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Impact of antinucleants on transdermal delivery of testosterone from a spray

Autor: Herve Rolland, Richard H. Guy, Patrick Wuthrich, Marie-Laure Leichtnam

Publikováno v: Journal of Pharmaceutical Sciences, Vol. 96, No 1 (2007) pp. 84-92

The goal was to explore whether the incorporation of antinucleant polymers into a testosterone spray formulation could stabilize a putative supersaturated state and improve the delivery of the drug across the skin. Several antinucleants were screened

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af3e87524d98d3a95c501243bb664b2
https://pubmed.ncbi.nlm.nih.gov/16998787

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Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility

Autor: Myriam Mirgaldi, Aarti Naik, Jean-Luc Veuthey, Nada Abla, Yogeshvar N. Kalia, Laurent Geiser, Richard H. Guy

Publikováno v: Journal of Pharmaceutical Sciences, Vol. 94, No 12 (2005) pp. 2667-75

The objective of the study was to investigate the relationship between transdermal iontophoretic flux--specifically, the electromigratory component--and electrophoretic mobility as determined by capillary zone electrophoresis (CZE). First, the steady

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b0f668da44caacd6f8750e2df9a848
https://pubmed.ncbi.nlm.nih.gov/16258982

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Skin permeation enhancement by sucrose esters: a pH-dependent phenomenon

Autor: Jennyfer Cázares-Delgadillo, Yogeshvar N. Kalia, David Quintanar-Guerrero, Adriana Ganem-Quintanar, Aarti Naik

Publikováno v: International Journal of Pharmaceutics, Vol. 297, No 1-2 (2005) pp. 204-12

The purpose of the present study was to evaluate the effect of sucrose esters (particularly, sucrose laureate and sucrose oleate in Transcutol) on the percutaneous penetration of a charged molecule as a function of ionization. We have investigated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a25a40f4ce0dc923c053544dbe4e6d
https://archive-ouverte.unige.ch/unige:22642

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Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability

Autor: Hilda A, Ayala-Bravo, David, Quintanar-Guerrero, Aarti, Naik, Yogeshvar N, Kalia, José M, Cornejo-Bravo, Adriana, Ganem-Quintanar

Publikováno v: Pharmaceutical Research, Vol. 20, No 8 (2003) pp. 1267-73

The purpose of this work was to 1) investigate the effect of sucrose esters (sucrose oleate and sucrose laureate in water or in Transcutol, TC) on the stratum corneum (SC) barrier properties in vivo and 2) examine the impact of these surfactant-like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b5ea09635dec3cb89762f13436d05f2
https://archive-ouverte.unige.ch/unige:21949

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