Head injury in older adults presenting to the ambulance service: who do we convey to the emergency department, and what clinical variables are associated with an intracranial bleed? A retrospective case–control study.

Autor: Barrett, J. W., Williams, J., Skene, S. S., Griggs, J. E., Bootland, D., Leung, J., Da Costa, A., Ballantyne, K., Davies, R., Lyon, R. M.

Publikováno v: Scandinavian Journal of Trauma, Resuscitation & Emergency Medicine; 10/31/2023, Vol. 31 Issue 1, p1-14, 14p

COVAC1 phase 2a expanded safety and immunogenicity study of a self-amplifying RNA vaccine against SARS-CoV-2

Autor: Szubert, AJ, Pollock, KM, Cheeseman, HM, Alagaratnam, J, Bern, H, Bird, O, Boffito, M, Byrne, R, Cole, T, Cosgrove, CA, Faust, SN, Fidler, S, Galiza, E, Hassanin, H, Kalyan, M, Libri, V, McFarlane, LR, Milinkovic, A, O'Hara, J, Owen, DR, Owens, D, Pacurar, M, Rampling, T, Skene, S, Winston, A, Woolley, J, Yim, YTN, Dunn, DT, McCormack, S, Shattock, RJ, COVAC 1 Study Team

Publikováno v: eClinicalMedicine. 56:101823

Background: lipid nanoparticle (LNP) encapsulated self-amplifying RNA (saRNA) is well tolerated and immunogenic in SARS-CoV-2 seronegative and seropositive individuals aged 18–75. Methods: a phase 2a expanded safety and immunogenicity study of a sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb1607ff605f0320f0c4d76cba21074
https://doi.org/10.1016/j.eclinm.2022.101823

The analysis of very small samples of repeated measurements

Autor: Skene, Simon Scott

The statistical analysis of repeated measures or longitudinal data always requires the accommodation of the covariance structure of the repeated measurements at some stage in the analysis. The general linear mixed model is often used for such analyse

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498629

Patients' and Clinicians' Perceptions of the Clinical Utility of Predictive Risk Models for Chemotherapy-Related Symptom Management: Qualitative Exploration Using Focus Groups and Interviews.

Autor: Miller M; Computer & Information Sciences, University of Strathclyde, Glasgow, United Kingdom., McCann L; Computer & Information Sciences, University of Strathclyde, Glasgow, United Kingdom., Lewis L; Johnson and Johnson Medical, Norderstedt, Germany., Miaskowski C; University of California, San Francisco, CA, United States., Ream E; School of Health Sciences, University of Surrey, Guildford, United Kingdom., Darley A; School of Medicine, University College Dublin, Dublin, Ireland., Harris J; School of Health Sciences, University of Surrey, Guildford, United Kingdom., Kotronoulas G; School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom., V Berg G; Department of Health Sciences, Norwegian University of Science and Technology, Gjøvik, Norway., Lubowitzki S; Department of Internal Medicine 1, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria., Armes J; School of Health Sciences, University of Surrey, Guildford, United Kingdom., Patiraki E; School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece., Furlong E; School of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland., Fox P; School of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland., Gaiger A; Department of Internal Medicine 1, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria., Cardone A; European Cancer Patient Coalition, Brussels, Belgium., Orr D; NHS 24, Glasgow, United Kingdom., Flowerday A; Docobo Limited, Leatherhead, United Kingdom., Katsaragakis S; School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece., Skene S; Surrey Clinical Trials Unit, University of Surrey, Guildford, United Kingdom., Moore M; Computer & Information Sciences, University of Strathclyde, Glasgow, United Kingdom., McCrone P; Department of Health Services and Population Research, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, United Kingdom., De Souza N; Population Health and Genomics, Medical School, University of Dundee, Dundee, United Kingdom., Donnan PT; Population Health and Genomics, Medical School, University of Dundee, Dundee, United Kingdom., Maguire R; Computer & Information Sciences, University of Strathclyde, Glasgow, United Kingdom.

Publikováno v: Journal of medical Internet research [J Med Internet Res] 2024 Jun 20; Vol. 26, pp. e49309. Date of Electronic Publication: 2024 Jun 20.

Diamorphine pharmacokinetics and conversion factor estimates for intranasal diamorphine in paediatric breakthrough pain:systematic review.

Autor: Gastine S; Great Ormond St Institute of Child Health, University College London, London, UK., Morse JD; Department of Pharmacology & Clinical Pharmacology, The University of Auckland Faculty of Medical and Health Sciences, Auckland, New Zealand., Leung MT; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, Hong Kong., Wong ICK; Research Department of Practice and Policy, University College London School of Pharmacy, London, UK., Howard RF; Department of Anaesthesia and Pain Medicine, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Harrop E; Helen and Douglas House Hospices, Oxford, UK., Liossi C; School of Psychology, University of Southampton, Southampton, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Standing JF; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Department of Immunity and Inflammation, University College London, London, UK., Jassal SS; Palliative Care, Rainbows Hospice for Children and Young Adults, Loughborough, UK., Hain RD; All-Wales Managed Clinical Network in Paediatric Palliative Medicine, Cardiff and Vale University Health Board, Cardiff, UK., Skene S; Faculty of Arts and Human Sciences, Surrey Clinical Trials Unit, University of Surrey, Guildford, UK., Oulton K; Centre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Law SL; Research Department of Practice and Policy, University College London School of Pharmacy, London, UK., Quek WT; Research Department of Practice and Policy, University College London School of Pharmacy, London, UK., Anderson BJ; Department of Anaesthesiology, The University of Auckland Faculty of Medical and Health Sciences, Auckland, New Zealand briana@adhb.govt.nz.

Publikováno v: BMJ supportive & palliative care [BMJ Support Palliat Care] 2024 Jan 08; Vol. 13 (e3), pp. e485-e493. Date of Electronic Publication: 2024 Jan 08.