Isolating the direct effects of adverse developmental conditions on in vivo cardiovascular function at adulthood: the avian model

Autor: Skeffington, KL, Beck, C, Itani, N, Giussani, DA

It is now well accepted that exposure to adverse environmental conditions in utero can predispose a fetus to disease later in life. Using an avian model to study the programming of disease has a unique advantage as it allows isolation of the direct e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1291a9c64b07ce4f04366643db46963

Chronic fetal hypoxaemia & maternal antioxidants: identifying mechanisms and treatments to improve postnatal lung structure & function in growth restricted offspring

Autor: 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI) Orlando, Florida 15-18 March 2017, McGillick, EV, Orgeig, S, Allison, BJ, Brain, KL, Niu, Y, Itani, N, Skeffington, KL, Beck, C, Botting, KJ, Giussani, DA, Morrison, JL

usc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1231::9404ac8f4502df10d9c981a741c2366a
https://hdl.handle.net/11541.2/138615

Differential effect of early versus late onset chronic hypoxemia on molecular mechanisms regulating lung maturation in the late gestation fetus

Autor: McGillick, EV, Orgeig, S, Allison, BJ, Brain, KL, Niu, Y, Itani, N, Skeffington, KL, Kane, AD, Herrera, EA, Giussani, DA, Morrison, JL

usc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1231::a2f5c695f6ce098d2d7f1c0e3227d134
https://hdl.handle.net/11541.2/138513

In vivo mitochondria-targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy.

Autor: Wang Z; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Aerospace Physiology, Fourth Military Medical University, Xi'an, China.; Department of Congenital Heart Disease, General Hospital of Northern Theater Command, Shenyang, China., Camm EJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia., Nuzzo AM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Surgical Sciences, University of Turin, Turin, Italy., Spiroski AM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK., Skeffington KL; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Ashmore TJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Rolfo A; Department of Surgical Sciences, University of Turin, Turin, Italy., Todros T; Department of Surgical Sciences, University of Turin, Turin, Italy., Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Ma J; Department of Aerospace Physiology, Fourth Military Medical University, Xi'an, China., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Niu Y; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK., Giussani DA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK.

Publikováno v: The Journal of physiology [J Physiol] 2024 Mar; Vol. 602 (6), pp. 1211-1225. Date of Electronic Publication: 2024 Feb 21.

Outcome monitoring and risk stratification after cardiac procedure in neonates, infants, children and young adults born with congenital heart disease: protocol for a multicentre prospective cohort study (Children OMACp).

Autor: Baquedano M; Translational Health Sciences, University of Bristol, Bristol, UK mai.baquedano@bristol.ac.uk.; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., de Jesus SE; Translational Health Sciences, University of Bristol, Bristol, UK., Rapetto F; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Murphy GJ; Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Unit in Cardiovascular Medicine, NIHR Leicester Biomedical Research Centre Cardiovascular Diseases, Leicester, East Midlands, UK., Angelini G; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.; Bristol Medical School, University of Bristol, Bristol, UK., Benedetto U; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Caldas P; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Srivastava PK; Imperial College London, London, UK., Uzun O; Cardiff and Vale NHS Trust, Cardiff, UK., Luyt K; Bristol Medical School, University of Bristol, Bristol, UK.; NICU, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, Avon, UK., Gonzalez Corcia C; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Taliotis D; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Stoica S; Bristol Royal Hospital for Children, Bristol, UK., Lawlor DA; Bristol Medical School, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Bamber AR; Bristol Medical School, University of Bristol, Bristol, UK.; North Bristol NHS Trust, Westbury on Trym, Bristol, UK., Perry A; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Skeffington KL; Bristol Heart Institute, University of Bristol, Bristol, UK., Omeje I; University Hospitals of Leicester NHS Trust, Leicester, UK., Pappachan J; PICU, Southampton Children's Hospital, Southampton, UK., Mumford AD; Department of Haematology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Coward RJM; Translational Health Sciences, University of Bristol, Bristol, UK., Kenny D; Children's Health Ireland at Crumlin, Dublin, Crumlin, Ireland., Caputo M; Translational Health Sciences, University of Bristol, Bristol, UK.; Bristol Heart Institute, University of Bristol, Bristol, UK.

Publikováno v: BMJ open [BMJ Open] 2023 Aug 08; Vol. 13 (8), pp. e071629. Date of Electronic Publication: 2023 Aug 08.