In vivo mitochondria-targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy.

Autor: Wang Z; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Aerospace Physiology, Fourth Military Medical University, Xi'an, China.; Department of Congenital Heart Disease, General Hospital of Northern Theater Command, Shenyang, China., Camm EJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia., Nuzzo AM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Surgical Sciences, University of Turin, Turin, Italy., Spiroski AM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK., Skeffington KL; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Ashmore TJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Rolfo A; Department of Surgical Sciences, University of Turin, Turin, Italy., Todros T; Department of Surgical Sciences, University of Turin, Turin, Italy., Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Ma J; Department of Aerospace Physiology, Fourth Military Medical University, Xi'an, China., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Niu Y; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK., Giussani DA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, Cambridge, UK.

Publikováno v: The Journal of physiology [J Physiol] 2024 Mar; Vol. 602 (6), pp. 1211-1225. Date of Electronic Publication: 2024 Feb 21.

Outcome monitoring and risk stratification after cardiac procedure in neonates, infants, children and young adults born with congenital heart disease: protocol for a multicentre prospective cohort study (Children OMACp).

Autor: Baquedano M; Translational Health Sciences, University of Bristol, Bristol, UK mai.baquedano@bristol.ac.uk.; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., de Jesus SE; Translational Health Sciences, University of Bristol, Bristol, UK., Rapetto F; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Murphy GJ; Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Unit in Cardiovascular Medicine, NIHR Leicester Biomedical Research Centre Cardiovascular Diseases, Leicester, East Midlands, UK., Angelini G; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.; Bristol Medical School, University of Bristol, Bristol, UK., Benedetto U; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Caldas P; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Srivastava PK; Imperial College London, London, UK., Uzun O; Cardiff and Vale NHS Trust, Cardiff, UK., Luyt K; Bristol Medical School, University of Bristol, Bristol, UK.; NICU, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, Avon, UK., Gonzalez Corcia C; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Taliotis D; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Stoica S; Bristol Royal Hospital for Children, Bristol, UK., Lawlor DA; Bristol Medical School, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Bamber AR; Bristol Medical School, University of Bristol, Bristol, UK.; North Bristol NHS Trust, Westbury on Trym, Bristol, UK., Perry A; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Skeffington KL; Bristol Heart Institute, University of Bristol, Bristol, UK., Omeje I; University Hospitals of Leicester NHS Trust, Leicester, UK., Pappachan J; PICU, Southampton Children's Hospital, Southampton, UK., Mumford AD; Department of Haematology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Coward RJM; Translational Health Sciences, University of Bristol, Bristol, UK., Kenny D; Children's Health Ireland at Crumlin, Dublin, Crumlin, Ireland., Caputo M; Translational Health Sciences, University of Bristol, Bristol, UK.; Bristol Heart Institute, University of Bristol, Bristol, UK.

Publikováno v: BMJ open [BMJ Open] 2023 Aug 08; Vol. 13 (8), pp. e071629. Date of Electronic Publication: 2023 Aug 08.

Molecular mechanisms underlying adverse effects of dexamethasone and betamethasone in the developing cardiovascular system.

Autor: Garrud TAC; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Teulings NEWD; Institute of Metabolic Science-Metabolic Research Laboratories, MRC Metabolic Diseases Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Niu Y; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Skeffington KL; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Beck C; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Itani N; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Conlon FG; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Botting KJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Nicholas LM; Institute of Metabolic Science-Metabolic Research Laboratories, MRC Metabolic Diseases Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Tong W; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Derks JB; Department of Perinatal Medicine, University Medical Centre, Utrecht, Netherlands., Ozanne SE; Institute of Metabolic Science-Metabolic Research Laboratories, MRC Metabolic Diseases Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.; BHF Cardiovascular Centre for Research Excellence, University of Cambridge, Cambridge, UK.; Strategic Research Initiative in Reproduction, University of Cambridge, Cambridge, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK., Giussani DA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; BHF Cardiovascular Centre for Research Excellence, University of Cambridge, Cambridge, UK.; Strategic Research Initiative in Reproduction, University of Cambridge, Cambridge, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Jun; Vol. 37 (6), pp. e22887.

Pathology-related changes in cardiac energy metabolites, inflammatory response and reperfusion injury following cardioplegic arrest in patients undergoing open-heart surgery.

Autor: Skeffington KL; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol, United Kingdom., Moscarelli M; National Heart and Lung Institute, Imperial College, London, United Kingdom.; GVM Care & Research, Anthea Hospital, Bari, Italy., Abdul-Ghani S; Department of Physiology, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine., Fiorentino F; Nightingale-Saunders Clinical Trials and Epidemiology Unit (King's Clinical Trials Unit), King's College London, London, United Kingdom., Emanueli C; National Heart and Lung Institute, Imperial College, London, United Kingdom., Reeves BC; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol, United Kingdom., Punjabi PP; National Heart and Lung Institute, Imperial College, London, United Kingdom., Angelini GD; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol, United Kingdom., Suleiman MS; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Publikováno v: Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Jul 22; Vol. 9, pp. 911557. Date of Electronic Publication: 2022 Jul 22 (Print Publication: 2022).

Fetal in vivo continuous cardiovascular function during chronic hypoxia

Autor: Allison, BJ, Brain, KL, Niu, Y, Kane, AD, Herrera, EA, Thakor, AS, Botting, KJ, Cross, CM, Itani, N, Skeffington, KL, Beck, C, Giussani, DA

Publikováno v: The Journal of Physiology

Key points The in vivo fetal cardiovascular defence to chronic hypoxia has remained by and large an enigma because no technology has been available to induce significant and prolonged fetal hypoxia whilst recording longitudinal changes in fetal regio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55e9494e871ebcd3710d3fced13cd891
http://europepmc.org/articles/PMC4771786