Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Skaist A"'
Autor:
Mindy K. Graham, Rulin Wang, Roshan Chikarmane, Bulouere Abel, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Jessica Hicks, Polina Sysa-Shah, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Yan Zhang, Michael Rubenstein, Kornel Schuebel, Brian W. Simons, Charles J. Bieberich, William G. Nelson, Shawn E. Lupold, Theodore L. DeWeese, Angelo M. De Marzo, Srinivasan Yegnasubramanian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study the disease evolution in human tissues.
Externí odkaz:
https://doaj.org/article/e570ed028e564316b359132fbf5d96e9
Akademický článek
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Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning techniques c
Externí odkaz:
http://arxiv.org/abs/1803.02398
Autor:
Sharma, Shivani1,2 (AUTHOR), Skaist Mehlman, Tamar1 (AUTHOR), Sagabala, Reddy Sudheer3 (AUTHOR), Boivin, Benoit3 (AUTHOR), Keedy, Daniel A.1,4,5 (AUTHOR) dkeedy@gc.cuny.edu
Publikováno v:
Acta Crystallographica: Section F, Structural Biology Communications. Jan2024, Vol. 80 Issue 1, p1-12. 12p.
Autor:
Bowland, Kirsten, Lai, Jiaying, Skaist, Alyza, Zhang, Yan, Teh, Selina Shiqing K., Roberts, Nicholas J., Thompson, Elizabeth, Wheelan, Sarah J., Hruban, Ralph H., Karchin, Rachel, Bailey, Matthew H., Iacobuzio-Donahue, Christine A., Eshleman, James R.
Publikováno v:
PLoS ONE; 12/19/2024, Vol. 19 Issue 12, p1-19, 19p
Autor:
Tamar Skaist Mehlman, Justin T Biel, Syeda Maryam Azeem, Elliot R Nelson, Sakib Hossain, Louise Dunnett, Neil G Paterson, Alice Douangamath, Romain Talon, Danny Axford, Helen Orins, Frank von Delft, Daniel A Keedy
Publikováno v:
eLife, Vol 12 (2023)
Much of our current understanding of how small-molecule ligands interact with proteins stems from X-ray crystal structures determined at cryogenic (cryo) temperature. For proteins alone, room-temperature (RT) crystallography can reveal previously hid
Externí odkaz:
https://doaj.org/article/aac320db06f049d18577b3ebd803e700
Autor:
Luchetti, Andrea, Forni, Giobbe, Martelossi, Jacopo, Savojardo, Castrense, Martelli, Pier Luigi, Casadio, Rita, Skaist, Alyza M., Wheelan, Sarah J., Mantovani, Barbara
Publikováno v:
In Genomics November 2021 113(6):4163-4172
Autor:
Laura A. Sena, Rajendra Kumar, David E. Sanin, Elizabeth A. Thompson, D. Marc Rosen, Susan L. Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes-Alexandre, Jessica L. Hicks, Tracy Jones, Kiara A. Bowers, Jillian N. Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W. Nathaniel Brennen, Sushant K. Kachhap, Emmanuel S. Antonarakis, Angelo M. De Marzo, John T. Isaacs, Mark C. Markowski, Samuel R. Denmeade
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA),
Externí odkaz:
https://doaj.org/article/1190b8e3606d4217ab6c491c95462033
Autor:
Teh, Selina Shiqing K, Bowland, Kirsten, Halper-Stromberg, Eitan, Kotwal, Akhil, Bennett, Alexis, Skaist, Alyza, Tang, Jacqueline, Cai, Fidel, Macoretta, Antonella, Liang, Hong, Kamiyama, Hirohiko, Wheelan, Sarah, Lin, Ming-Tseh, Hruban, Ralph H, Hung, Chien-Fu, Goldstein, Michael, Scharpf, Robert B, Roberts, Nicholas J, Eshleman, James R
Publikováno v:
NAR Cancer; Jun2024, Vol. 6 Issue 2, p1-14, 14p
Publikováno v:
Zoological Letters, Vol 5, Iss 1, Pp 1-13 (2019)
Abstract Background The crustacean class Branchiopoda includes fairy shrimps, clam shrimps, tadpole shrimps, and water fleas. Branchiopods, which are well known for their great variety of reproductive strategies, date back to the Cambrian and extant
Externí odkaz:
https://doaj.org/article/ce125834dff2424a9a733ee741b1700a