Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Sjur Olsnes"'
Autor:
Torunn Sletten, Michal Kostas, Joanna Bober, Vigdis Sorensen, Mandana Yadollahi, Sjur Olsnes, Justyna Tomala, Jacek Otlewski, Malgorzata Zakrzewska, Antoni Wiedlocha
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90687 (2014)
Extracellular fibroblast growth factor 1 (FGF1) acts through cell surface tyrosine kinase receptors, but FGF1 can also act directly in the cell nucleus, as a result of nuclear import of endogenously produced, non-secreted FGF1 or by transport of extr
Externí odkaz:
https://doaj.org/article/ac0b9c0aa6724c348ef5f21a69f124c7
Autor:
Ellen Margrethe Haugsten, Malgorzata Zakrzewska, Andreas Brech, Sascha Pust, Sjur Olsnes, Kirsten Sandvig, Jørgen Wesche
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21708 (2011)
Endocytosis of tyrosine kinase receptors can influence both the duration and the specificity of the signal emitted. We have investigated the mechanisms of internalization of fibroblast growth factor receptor 3 (FGFR3) and compared it to that of FGFR1
Externí odkaz:
https://doaj.org/article/17ece21e1d5642c1b53cb7aee200f413
Autor:
Yixin Jin, Yan Zhen, Camilla Skiple Skjerpen, Antoni Wiedlocha, Ellen Margrethe Haugsten, Sébastien Wälchli, Vigdis Sørensen, Sjur Olsnes
Publikováno v:
Traffic. 13:650-664
Fibroblast growth factor 1 (FGF1) taken up by cells into endocytic vesicles can be translocated across vesicular membranes into the cytosol and the nucleus where it has a growth regulatory activity. Previously, leucine-rich repeat containing 59 (LRRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::203cdd5541f2ae57b72c3450088fac8b
https://doi.org/10.1111/j.1600-0854.2012.01341.x
https://doi.org/10.1111/j.1600-0854.2012.01341.x
Publikováno v:
Experimental Cell Research. 317:1005-1015
Fibroblast growth factor 1 (FGF1) has the property to become translocated from the extracellular space into the cell cytosol and nucleus. Membrane translocation of FGF1 occurs subsequent to endocytic uptake and is strictly FGF-receptor (FGFR) depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5daed000ce46b2bc075701b874a96e5
https://doi.org/10.1016/j.yexcr.2011.01.003
https://doi.org/10.1016/j.yexcr.2011.01.003
Autor:
Rosario Iglesias, Yolanda Pérez, Sjur Olsnes, Augusto Parente, Pilar Jiménez, Antimo Di Maro, Manuel J. Gayoso, Rachele Tamburino, Lucía Citores, J. Miguel Ferreras, Tomás Girbés
Publikováno v:
Biochimie. 92:71-80
Sialic acid-binding dwarf elder agglutinin (SEA) present only in rhizomes of the medicinal plant Sambucus ebulus L., was found to be a tetrameric glycoprotein consisting of two covalently-associated dimers of an enzymic A chain with rRNA N-glycosidas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae289517772fd0c7b22dc9db1e638bf6
https://doi.org/10.1016/j.biochi.2009.09.011
https://doi.org/10.1016/j.biochi.2009.09.011
Autor:
Anna Szlachcic, Malgorzata Zakrzewska, Sjur Olsnes, Jacek Otlewski, Antoni Wiedlocha, Daniel Krowarsch
Publikováno v:
The Journal of Biological Chemistry
Human FGF1 (fibroblast growth factor 1) is a powerful signaling molecule with a short half-life in vivo and a denaturation temperature close to physiological. Binding to heparin increases the stability of FGF1 and is believed to be important in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c05a6655602bb98d2f2a124684c52c0
https://doi.org/10.1074/jbc.m109.001289
https://doi.org/10.1074/jbc.m109.001289
Publikováno v:
Biochemistry. 48:7209-7218
After binding to its receptor on the surface of mammalian cells and subsequent endocytosis, FGF1 is translocated across the membrane into the cytosol. The growth factor is then further transported into the nucleus. In order to characterize more close
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36381321e181a1f31aa02e6f0e650cc
https://doi.org/10.1021/bi9007353
https://doi.org/10.1021/bi9007353
Autor:
Jørgen Wesche, Ellen Margrethe Haugsten, Sjur Olsnes, Sunniva Maria Stordal Bjørklund, Jędrzej Małecki
Publikováno v:
Molecular Biology of the Cell. 19:3390-3403
Endocytosis and targeting of growth factor receptors for lysosomal degradation have been associated with ubiquitination of the intracellular part of the receptors. To elucidate the role of receptor ubiquitination in internalization and sorting of fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5ccdc43805d934315255c0b649faf9
https://doi.org/10.1091/mbc.e07-12-1219
https://doi.org/10.1091/mbc.e07-12-1219
Autor:
Sébastien Wälchli, Trine Nilsen, Vigdis Sørensen, Antoni Wiedlocha, Yan Zhen, Ellen Margrethe Haugsten, Malgorzata Zakrzewska, Sjur Olsnes
Publikováno v:
Molecular and Cellular Biology. 28:4129-4141
Exogenous fibroblast growth factor 1 (FGF1) signals through activation of transmembrane FGF receptors (FGFRs) but may also regulate cellular processes after translocation to the cytosol and nucleus of target cells. Translocation of FGF1 occurs across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3922248703073d3c3ae4f09cfe00ad
https://doi.org/10.1128/mcb.02117-07
https://doi.org/10.1128/mcb.02117-07