In vivo and in vitro Approaches Reveal Novel Insight Into the Ability of Epicardium-Derived Cells to Create Their Own Extracellular Environment

Autor: Noortje A. M. Bax, Sjoerd N. Duim, Boudewijn P. T. Kruithof, Anke M. Smits, Carlijn V. C. Bouten, Marie José Goumans

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 6 (2019)

Human epicardium-derived cells (hEPDCs) transplanted in the NOD-SCID mouse heart after myocardial infarction (MI) are known to improve cardiac function, most likely orchestrated by paracrine mechanisms that limit adverse remodeling. It is not yet kno

Externí odkaz: https://doaj.org/article/c7f082e7a03047bbb22c8b5748f2374f

'Macro transcobalamin causing raised vitamin B12

Autor: Sjoerd N. Duim, L. Tom Vlasveld, Stephanie T.P. Mezger, Alma M.A. Mingels, Christian R.B. Ramakers, Douwe de Boer, Sandra G. Heil, Ebba Nexo, André P. van Rossum

Publikováno v: Annals of Clinical Biochemistry, 59(4), 302-307. SAGE Publications Ltd
Annals of Clinical Biochemistry, 59(4):00045632221087132, 302-307. SAGE Publications Inc.
Duim, S N, Vlasveld, L T, Mezger, S T P, Mingels, A M A, Ramakers, C R B, de Boer, D, Heil, S G, Nexo, E & van Rossum, A P 2022, ' “Macro transcobalamin causing raised vitamin B12 : Case-based laboratory investigation" ', Annals of Clinical Biochemistry, vol. 59, no. 4, pp. 302-307 . https://doi.org/10.1177/00045632221087132

Determination of plasma vitamin B12 (B12) is a frequently requested laboratory analysis, mainly employed to establish B12 deficiency. However, an increased level of B12 is a common unexpected finding that may be related to an increased concentration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d83349e7c45166a69ceb4879bc7a21
http://www.scopus.com/inward/record.url?scp=85130012797&partnerID=8YFLogxK

Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks during Development

Autor: Sjoerd N. Duim, Anna M. D. Végh, Marco C. DeRuiter, Anke M. Smits, Robert E. Poelmann, Arend D. J. ten Harkel, Monique R.M. Jongbloed, Marie-José Goumans

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 3, Iss 3, p 28 (2016)
Journal of Cardiovascular Development and Disease

The autonomic nervous system (cANS) is essential for proper heart function, and complications such as heart failure, arrhythmias and even sudden cardiac death are associated with an altered cANS function. A changed innervation state may underlie (par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf79d095c8beab7410ce68c6c713de7
http://www.mdpi.com/2308-3425/3/3/28

TGFβ and BMP signaling in cardiac cushion formation: Lessons from mice and chicken

Autor: Boudewijn P.T. Kruithof, Asja T. Moerkamp, Marie-José Goumans, Sjoerd N. Duim

Publikováno v: Differentiation, 84(1)
Differentiation, 84(1), 89-102

Cardiac cushion formation is crucial for both valvular and septal development. Disruption in this process can lead to valvular and septal malformations, which constitute the largest part of congenital heart defects. One of the signaling pathways that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efe55226cfb14174bdeeb2c172e5afe
https://doi.org/10.1016/j.diff.2012.04.003

Regional differences in WT-1 and Tcf21 expression during ventricular development: implications for myocardial compaction

Autor: Boudewijn P.T. Kruithof, Bin Zhou, Lambertus J. Wisse, Marie-José Goumans, Adriana C. Gittenberger-de Groot, Robert E. Poelmann, Michelle D. Tallquist, Sjoerd N. Duim, Roderick W.C. Scherptong, Monique R.M. Jongbloed, William T. Pu, Martin J. Schalij, Rebecca Vicente-Steijn

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0136025 (2015)

Background Morphological and functional differences of the right and left ventricle are apparent in the adult human heart. A differential contribution of cardiac fibroblasts and smooth muscle cells (populations of epicardium-derived cells) to each ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d3e2fb266ca1f3fb59198294f16611
https://hdl.handle.net/1887/107239