Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sjoerd J. Klaasen"'
Autor:
Sjoerd J. Klaasen, Geert J. P. L. Kops
Publikováno v:
Cells, Vol 11, Iss 22, p 3564 (2022)
Aneuploidy is a hallmark of cancer and a major cause of miscarriages in humans. It is caused by chromosome segregation errors during cell divisions. Evidence is mounting that the probability of specific chromosomes undergoing a segregation error is n
Externí odkaz:
https://doaj.org/article/1d4cce1dc02349f3950f685659fd19bb
Autor:
Wilma H. M. Hoevenaar, Aniek Janssen, Ajit I. Quirindongo, Huiying Ma, Sjoerd J. Klaasen, Antoinette Teixeira, Bastiaan van Gerwen, Nico Lansu, Folkert H. M. Morsink, G. Johan A. Offerhaus, René H. Medema, Geert J. P. L. Kops, Nannette Jelluma
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Aneuploidy caused by chromosomal instability is frequently observed in cancer, but little is known about its contribution to tumor development. Here, the authors show that in the mouse intestine, the consequences of aneuploidy are exquisitely depende
Externí odkaz:
https://doaj.org/article/118f25f0a18f4b6ea689450fb6a3c626
Autor:
Hoyee Tsui, Sebastiaan Johannes van Kampen, Su Ji Han, Viviana Meraviglia, Willem B. van Ham, Simona Casini, Petra van der Kraak, Aryan Vink, Xiaoke Yin, Manuel Mayr, Alexandre Bossu, Gerard A. Marchal, Jantine Monshouwer-Kloots, Joep Eding, Danielle Versteeg, Hesther de Ruiter, Karel Bezstarosti, Judith Groeneweg, Sjoerd J. Klaasen, Linda W. van Laake, Jeroen A.A. Demmers, Geert J.P.L. Kops, Christine L. Mummery, Toon A.B. van Veen, Carol Ann Remme, Milena Bellin, Eva van Rooij
Publikováno v:
Science Translational Medicine, 15(688):eadd4248. American Association for the Advancement of Science
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiac disease. Many patients with ACM harbor mutations in desmosomal genes, predominantly in plakophilin-2 ( PKP2 ). Although the genetic basis of ACM is well characterized, the underl
Autor:
Sjoerd J. Klaasen, My Anh Truong, Richard H. van Jaarsveld, Isabella Koprivec, Valentina Štimac, Sippe G. de Vries, Patrik Risteski, Snježana Kodba, Kruno Vukušić, Kim L. de Luca, Joana F. Marques, Elianne M. Gerrits, Bjorn Bakker, Floris Foijer, Jop Kind, Iva M. Tolić, Susanne M. A. Lens, Geert J. P. L. Kops
Publikováno v:
Nature
Nature, 607, 604-609
Nature, 607, pp. 604-609
Nature, 607(7919), 604-609. Nature Publishing Group
Nature, 607, 604-609
Nature, 607, pp. 604-609
Nature, 607(7919), 604-609. Nature Publishing Group
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis [1, 2, 3, 4, 5]. Selective pressures then shape distinct aneuploidy and rearrange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaaba46aeec6daf7ebdc7fd431951dd
http://fulir.irb.hr/7580/
http://fulir.irb.hr/7580/
Autor:
Sjoerd J, Klaasen, My Anh, Truong, Richard H, van Jaarsveld, Isabella, Koprivec, Valentina, Štimac, Sippe G, de Vries, Patrik, Risteski, Snježana, Kodba, Kruno, Vukušić, Kim L, de Luca, Joana F, Marques, Elianne M, Gerrits, Bjorn, Bakker, Floris, Foijer, Jop, Kind, Iva M, Tolić, Susanne M A, Lens, Geert J P L, Kops
Publikováno v:
Nature. 607(7919)
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis
Autor:
Ana C.F. Bolhaqueiro, Nizar Hami, Devanjali Dutta, Nobuo Sasaki, Onno Kranenburg, Judith Vivié, Marc van de Wetering, Peter M. Lansdorp, Robert G.J. Vries, Alexander van Oudenaarden, Geert J. P. L. Kops, Hans Clevers, Diana C.J. Spierings, Hugo J. Snippert, Ingrid Verlaan-Klink, Bas Ponsioen, Emre Kucukkose, Richard H. van Jaarsveld, Bjorn Bakker, Sjoerd J Klaasen, Floris Foijer, Sylvia F. Boj
Publikováno v:
Nature Genetics, 51(5), 824-834. Nature Publishing Group
Nature Genetics, 51(5), 824. Nature Publishing Group
Nature Genetics
Nature Genetics, 51(5), 824. Nature Publishing Group
Nature Genetics
Chromosome segregation errors cause aneuploidy and genomic heterogeneity, which are hallmarks of cancer in humans. A persistent high frequency of these errors (chromosomal instability (CIN)) is predicted to profoundly impact tumor evolution and thera
Autor:
Bastiaan van Gerwen, Aniek Janssen, Nico Lansu, Nannette Jelluma, Huiying Ma, Sjoerd J. Klaasen, G. Johan A. Offerhaus, Wilma H. M. Hoevenaar, René H. Medema, Antoinette Teixeira, Ajit I. Quirindongo, Folkert H.M. Morsink, Geert J. P. L. Kops
Publikováno v:
Nature Communications, 11(1). Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature communications, 11(1):1501. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature communications, 11(1):1501. Nature Publishing Group
Most human cancers are aneuploid, due to a chromosomal instability (CIN) phenotype. Despite being hallmarks of cancer, however, the roles of CIN and aneuploidy in tumor formation have not unequivocally emerged from animal studies and are thus still u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc420f5030dfd4d9453dee67bf91194
https://pure.knaw.nl/portal/en/publications/063362bd-942f-4f69-bda1-4dbddc1b2dcc
https://pure.knaw.nl/portal/en/publications/063362bd-942f-4f69-bda1-4dbddc1b2dcc
Autor:
Sjoerd J. Klaasen, Geert J. P. L. Kops, René H. Medema, G. Johan A. Offerhaus, Aniek Janssen, Antoinette Teixeira, Nannette Jelluma, Ajit I. Quirindongo, Wilma H. M. Hoevenaar, Huiying Ma
Most human cancers are aneuploid, due to a chromosomal instability (CIN) phenotype. Despite being hallmarks of cancer, however, the roles of CIN and aneuploidy in tumor formation have not unequivocally emerged from animal studies and are thus still u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4c4a44dbd98c3c1ea03a888094a702