Limited numbers of apoptotic cells in fresh paraffin embedded bone marrow samples of patients with myelodysplastic syndrome

Autor: J.Th.M de Wolf, Edo Vellenga, A.A. van de Loosdrecht, Sjl Brada, J Koudstaal

Publikováno v: Leukemia Research, 28(9), 921-5. Elsevier Limited
Brada, SJ, van de Loosdrecht, A A, Koudstaal, J, de Wolf, JT & Vellenga, E 2004, ' Limited numbers of apoptotic cells in fresh paraffin embedded bone marrow samples of patients with myelodysplastic syndrome. ', Leukemia Research, vol. 28, no. 9, pp. 921-5 . https://doi.org/10.1016/j.leukres.2004.01.001
Leukemia Research, 28(9), 921-925. PERGAMON-ELSEVIER SCIENCE LTD

In myelodysplasia (MDS) the precise mechanism of ineffective erythropoiesis is not fully elucidated, but it is suggested that apoptosis may contribute to this process. We performed TdT-mediated dUTP-nick end labelling (TUNEL) staining of paraffin emb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7a34be55f97657602b0f3cc7720847
https://doi.org/10.1016/j.leukres.2004.01.001

CD34+/CD36- cells from myelodysplasia patients have a limited capacity to proliferate but can differentiate in response to Epo and MGF stimulation

Autor: SJL Brada, JThW de Wolf, DW Hendriks, JW Smit, E Vellenga

Publikováno v: Leukemia. 12(6)

Myelodysplasia (MDS) is mostly characterized by a normal or increased number of normoblasts in the bone marrow and an impaired in vitro colony formation. In the present study we analyzed whether this might be due to a disconnection between proliferat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99744d2a5bc03d5b4f06c3076d169ec5
https://pubmed.ncbi.nlm.nih.gov/10086748

Ischaemic colitis and lung infiltrates caused by extramedullary haematopoiesis in a patient with an acute erythroid leukaemia following polycythaemia vera

Autor: de Joseph Wolf, Edo Vellenga, Sibrand Poppema, Sjl Brada

Publikováno v: Netherlands Journal of Medicine, 52(4), 142-146. van Zuiden Communications BV.

A patient with 'spent' polycythaemia vera showed extensive extramedullary haematopoiesis (EMH) in non-haematopoietic tissue clinically resulting in an ischaemic colitis and respiratory symptoms due to lung infiltrates. On laboratory investigation, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50589ca5568bc21b265ab2f70a1cf45d
https://research.rug.nl/en/publications/2d354d3f-907c-46a9-94cd-89bd86d97417

91 Ferrokinetic studies in myelodysplasia suggests a dissociation of proliferation and differentiation in erythropoiesis

Autor: Edo Vellenga, J. de Wolf, Sjl Brada, H Louwes, Dw Hendriks

Publikováno v: Leukemia Research. 21:S24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6bcfa413c4f9c41ee5311349611d04d
https://doi.org/10.1016/s0145-2126(97)81306-9