Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Sjef Verbeek"'
Autor:
Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background Osteoclast-mediated bone erosion is a central feature of rheumatoid arthritis (RA). Immune complexes, present in a large percentage of patients, bind to Fcγ receptors (FcγRs), thereby modulating the activity of immune cells. In
Externí odkaz:
https://doaj.org/article/9d7253effde542e1a9c44878e23e232e
Autor:
Sarah Legrain, Dan Su, Mélanie Gaignage, Cor Breukel, Jill Claassens, Conny Brouwers, Margot M. Linssen, Shozo Izui, J. Sjef Verbeek, Jean-Paul Coutelier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9027 (2021)
Infection with viruses, such as the lactate dehydrogenase-elevating virus (LDV), is known to trigger the onset of autoimmune anemia through the enhancement of the phagocytosis of autoantibody-opsonized erythrocytes by activated macrophages. Type I in
Externí odkaz:
https://doaj.org/article/05d1f73350e14162a0a908ea3ebb3380
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
FcγRIIb is the only inhibitory Fc receptor and controls many aspects of immune and inflammatory responses. The observation 19 years ago that FcγRIIb−/− mice generated by gene targeting in 129 derived ES cells developed severe lupus like disease
Externí odkaz:
https://doaj.org/article/48479f3e90944506a71ff0c4f1909a13
Autor:
Jan Willem Kleinovink, Laura Mezzanotte, Giorgia Zambito, Marieke F. Fransen, Luis J. Cruz, J. Sjef Verbeek, Alan Chan, Ferry Ossendorp, Clemens Löwik
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Non-invasive imaging technologies to visualize the location and functionality of T cells are of great value in immunology. Here, we describe the design and generation of a transgenic mouse in which all T cells constitutively express green-emitting cl
Externí odkaz:
https://doaj.org/article/77df4fbc1b0a4f46ae5f8867a008bea7
Autor:
Thorbald van Hall, Janine Schuurman, J. Sjef Verbeek, Mischa A. Houtkamp, Danita H. Schuurhuis, Aran F. Labrijn, Sandra Verploegen, Marjolein Sluijter, Işıl Altıntaş, Hreinn Benonisson
Dynamics of T cell distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166bcba5273f3781111e8bfd9926e802
https://doi.org/10.1158/1535-7163.22509997.v1
https://doi.org/10.1158/1535-7163.22509997.v1
Autor:
Thorbald van Hall, Janine Schuurman, J. Sjef Verbeek, Mischa A. Houtkamp, Danita H. Schuurhuis, Aran F. Labrijn, Sandra Verploegen, Marjolein Sluijter, Işıl Altıntaş, Hreinn Benonisson
legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7938e70eb122393150fa73261d93df16
https://doi.org/10.1158/1535-7163.22509994.v1
https://doi.org/10.1158/1535-7163.22509994.v1
Autor:
Thorbald van Hall, Janine Schuurman, J. Sjef Verbeek, Mischa A. Houtkamp, Danita H. Schuurhuis, Aran F. Labrijn, Sandra Verploegen, Marjolein Sluijter, Işıl Altıntaş, Hreinn Benonisson
Immunotherapy of cancer with CD3-targeting bispecific antibodies (CD3 bsAb) is a fast developing field, and multiple tumor-associated antigens (TAA) are evaluated for hematologic and solid malignancies. The efficacy of these CD3 bsAb is usually exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d15e11b2ea3ff43ef4500bd633da2e0
https://doi.org/10.1158/1535-7163.c.6539473.v1
https://doi.org/10.1158/1535-7163.c.6539473.v1
Autor:
Marcel Veltrop, Laura van Vliet, Margriet Hulsker, Jill Claassens, Conny Brouwers, Cor Breukel, Jos van der Kaa, Margot M Linssen, Johan T den Dunnen, Sjef Verbeek, Annemieke Aartsma-Rus, Maaike van Putten
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193289 (2018)
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease generally caused by reading frame disrupting mutations in the DMD gene resulting in loss of functional dystrophin protein. The reading frame can be restored by antisense oligonucleo
Externí odkaz:
https://doaj.org/article/7d1b65ae6d9a47e096721b71e3330f69
Autor:
Zoltán Bánki, Roland Werner, Lydia Riepler, Annika Rössler, Brigitte Müllauer, Verena Hegen, Wibke Bayer, J. Sjef Verbeek, Ulf Dittmer, Heribert Stoiber
Publikováno v:
Viruses, Vol 11, Iss 2, p 145 (2019)
Dendritic cells (DCs) express Fcγ receptors (FcγRs) for the binding immune complexes (ICs) consisting of IgG and antigens (Ags). IC⁻FcγR interactions have been demonstrated to enhance activation and antigen-presenting functions of DCs. Utilizing
Externí odkaz:
https://doaj.org/article/ce5cd66fc6d74dbe8ef4ef974b2b5e2b
Autor:
Mehmet, Sahin, Melissa M, Remy, Benedict, Fallet, Rami, Sommerstein, Marianna, Florova, Anna, Langner, Katja, Klausz, Tobias, Straub, Mario, Kreutzfeldt, Ingrid, Wagner, Cinzia T, Schmidt, Pauline, Malinge, Giovanni, Magistrelli, Shozo, Izui, Hanspeter, Pircher, J Sjef, Verbeek, Doron, Merkler, Matthias, Peipp, Daniel D, Pinschewer
Publikováno v:
Cell reports. 38(5)
Across the animal kingdom, multivalency discriminates antibodies from all other immunoglobulin superfamily members. The evolutionary forces conserving multivalency above other structural hallmarks of antibodies remain, however, incompletely defined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a6a1a9f5f4d2dfd4840cdf274d9df80
https://pubmed.ncbi.nlm.nih.gov/35108544
https://pubmed.ncbi.nlm.nih.gov/35108544