Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Siyue Ma"'
Publikováno v:
ACS Omega, Vol 9, Iss 23, Pp 24406-24414 (2024)
Externí odkaz:
https://doaj.org/article/8cf98c16ea2a43aba4040d71c3af1b4d
Publikováno v:
Chemical & Biomedical Imaging, Vol 2, Iss 6, Pp 401-412 (2024)
Externí odkaz:
https://doaj.org/article/b3e7c500c6e647e2891a44e91f04e71d
Autor:
Tangkai Qi, Fang Chen, Siyue Ma, Renfang Zhang, Li Liu, Zhenyan Wang, Yang Tang, Wei Song, Jianjun Sun, Junyang Yang, Shuibao Xu, Bihe Zhao, Yinzhong Shen, Jun Chen
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 6, Pp 1667-1675 (2023)
Abstract Introduction Cryptococcal meningitis (CM) is a serious and fatal fungal infection that affects individuals infected with human immunodeficiency virus (HIV). Despite treatment, recurrence of symptoms is common and could lead to poor outcomes.
Externí odkaz:
https://doaj.org/article/9fcaa182eaf844eeb4958dd703b96b05
Autor:
Siyue Ma, Ji Hyeon Kim, Wei Chen, Lu Li, Jieun Lee, Junlian Xue, Yuxia Liu, Guang Chen, Bo Tang, Wei Tao, Jong Seung Kim
Publikováno v:
Advanced Science, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract Targeting cancer cells with high specificity is one of the most essential yet challenging goals of tumor therapy. Because different surface receptors, transporters, and integrins are overexpressed specifically on tumor cells, using these tum
Externí odkaz:
https://doaj.org/article/d6344747d1224b099996e6ec99a33863
Autor:
Hongwu Liu, Shan Yang, Ting Li, Siyue Ma, Peiyi Wang, Guoqing Wang, Shanshan Su, Yue Ding, Linli Yang, Xiang Zhou, Song Yang
Publikováno v:
Molecules, Vol 28, Iss 6, p 2442 (2023)
Imidazole alkaloids, a common class of five-membered aromatic heterocyclic compounds, exist widely in plants, animals and marine organisms. Because of imidazole’s extensive and excellent biological and pharmacological activities, it has always been
Externí odkaz:
https://doaj.org/article/a6f6178337a442359996a83cf239a931
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
As a critical member of G protein-coupled receptors (GPCRs), G protein-coupled receptor 120 (GPR120) is a potential target for many physiological diseases, such as type 2 diabetes mellitus, inflammation, and obesity. Considering that small-molecule f
Externí odkaz:
https://doaj.org/article/2ff6a96b5bef433cb2caa7edcd040172
Autor:
Tongliang Zhou, Siyue Ma, Fady Nahra, Alan M.C. Obled, Albert Poater, Luigi Cavallo, Catherine S.J. Cazin, Steven P. Nolan, Michal Szostak
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101377- (2020)
Summary: The development of more reactive, general, easily accessible, and readily available Pd(II)–NHC precatalysts remains a key challenge in homogeneous catalysis. In this study, we establish air-stable NHC–Pd(II) chloro-dimers, [Pd(NHC)(μ-Cl
Externí odkaz:
https://doaj.org/article/b4d8781e3aac49f0ab98ee5cece281d1
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 1, Pp 235-244 (2018)
Background/Aims: TP63 was believed to play an important role in the development of many malignancies, while the polymorphisms located at the miRNA binding sites within the 3’UTR of TP63 mRNA may interfere with its expression. In this study, we aime
Externí odkaz:
https://doaj.org/article/bd474699ee4a4a3fb028491c09119609
Publikováno v:
Chemical Communications. 59:5599-5602
We propose an intramolecular synergistic counteracting strategy of fluorescence resonance energy transfer and the inner filter effect for accurate photoactivation monitoring, to eliminate the influence of the biological microenvironment.
Publikováno v:
Journal of Medicinal Chemistry. 66:733-751
Targeted protein degradation (TPD) strategies open up new avenues for therapeutics and provide powerful tools for biological inquiry. Herein, we present a brand-new approach, termed heat shock protein 90 (HSP90)-mediated targeting chimeras (HEMTACs),